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561.
Distribution of 10 periodontal bacteria in saliva samples from Japanese children and their mothers 总被引:1,自引:0,他引:1
Tamura K Nakano K Hayashibara T Nomura R Fujita K Shintani S Ooshima T 《Archives of oral biology》2006,51(5):371-377
OBJECTIVE: We analyzed the distribution of 10 periodontal bacteria species (Porphyromonas gingivalis, Tannerella forsythensis, Prevotella intermedia, Prevotella nigrescens, Campylobacter rectus, Eikenella corrodens, Actinobacillus actinomycetemcomitans, Capnocytophaga ochracea, Capnocytophaga sputigena, and Treponema denticola) in children, and then compared their distribution in those children and their mothers, with special attention given to three of the species known as the red complex (P. gingivalis, T. forsythensis, and T. denticola) whose presence has been shown to be associated with conditions related to periodontal diseases. METHODS: One hundred thirteen pairs of children and their mothers were randomly selected from patients treated at the Pedodontic Clinic of Osaka University Dental Hospital. Saliva samples were taken at the second visit prior to receiving professional tooth brushing instruction. Genomic DNA was extracted from each saliva sample, followed by a polymerase chain reaction assay with species-specific sets of primers. RESULTS: A. actinomycetemcomitans was the most frequently detected species in the mothers, followed by C. sputigena, P. gingivalis, and T. forsythensis, while C. sputigena had the highest detection rate, followed by A. actinomycetemcomitans and T. denticola in the children. The detection rate of the red complex species in children whose mothers possessed the same species was significantly higher than in those whose mothers did not possess them. CONCLUSIONS: Our results indicate a correlation between the presence of periodontal bacteria in children and their mothers, while the presence of red complex bacteria in children was highly associated with that in their mothers. 相似文献
562.
Junichi Matsuzaki Toshihiko Torigoe Yoshihiko Hirohashi Yasuaki Tamura Hiroko Asanuma Emiri Nakazawa Eri Saka Kazuyo Yasuda Shuji Takahashi Noriyuki Sato 《Pathology international》2013,63(8):391-397
We have shown that ECRG4 suppressed Fas‐induced apoptosis in Jurkat cells. ECRG4 mRNA expression was ubiquitously detected in normal adult human tissues, suggesting that ECRG4 plays a major role in human tissues. ECRG4 mRNA expression was down‐regulated in tumor cells. Expression of ECRG4 suppressed cell growth. We established an anti‐ECRG4 monoclonal antibody. Our immunohistochemical analysis demonstrated that ECRG4‐positive cells tended to be distributed in the region that was negative for Ki‐67 in esophageal squamous cell carcinoma tissues. There was a significant inverse correlation between ECRG4 expression and Ki‐67 labeling index in esophageal squamous cell carcinoma. This study provides the first functional evidence for an association of endogenous expression of ECRG4 with cell proliferation. ECRG4 is a candidate tumor suppressor gene that might be involved in the proliferation of esophageal squamous cell carcinoma. 相似文献
563.
Kazue Okamoto-Mizuno Kazuyo Tsuzuki Koh Mizuno Yasushi Ohshiro 《European journal of applied physiology》2009,105(2):191-197
The effects of cold exposure on heart rate variability (HRV) during sleep were examined. Eight male subjects slept under three
different conditions: 3°C, 50–80% relative humidity (RH) [3]; 10°C, 50% RH [10]; and 17°C 50% RH [17]. No significant differences
were observed in HRV during rapid eye movement sleep (REM) and wakefulness. The ratio of the low frequency (LF) to high frequency
component (HF) of HRV (LF/HF) significantly differed among the conditions during stage 2 and slow wave sleep (SWS) that decreased
as the ambient temperature decreased. The normalized LF [LF/(LF + HF)] significantly decreased in 3 and 10 than in 17 during
SWS. In low ambient temperature, predominant cardiac parasympathetic activity during stage 2 with no significant difference
during REM and wakefulness may cause variations in HRV at transition from stage 2 to REM and wakefulness. These results may
partly explain the peak in adverse cardiac events during winter. 相似文献
564.
Seiji Kimura Seiji Ohtori Sumihisa Orita Gen Inoue Yawara Eguchi Masashi Takaso Nobuyasu Ochiai Kazuki Kuniyoshi Yasuchika Aoki Tetsuhiro Ishikawa Masayuki Miyagi Hiroto Kamoda Miyako Suzuki Yoshihiro Sakuma Gou Kubota Yasuhiro Oikawa Kazuhide Inage Takeshi Sainoh Kazuyo Yamauchi Tomoaki Toyone Junichi Nakamura Shunji Kishida Jun Sato Kazuhisa Takahashi 《Yonsei medical journal》2014,55(2):487-492
Purpose
Bupivacaine is commonly used for the treatment of back pain and the diagnosis of its origin. Nonunion is sometimes observed after spinal fusion surgery; however, whether the nonunion causes pain is controversial. In the current study, we aimed to detect painful nonunion by injecting bupivacaine into the disc space of patients with nonunion after anterior lumbar interbody fusion (ALIF) surgery for discogenic low back pain.Materials and Methods
From 52 patients with low back pain, we selected 42 who showed disc degeneration at only one level (L4-L5 or L5-S1) on magnetic resonance imaging and were diagnosed by pain provocation on discography and pain relief by discoblock (the injection of bupivacaine). They underwent ALIF surgery. If the patients showed low back pain and nonunion 2 years after surgery, we injected bupivacaine into the nonunion disc space. Patients showing pain relief after injection of bupivacaine underwent additional posterior fixation using pedicle screws. These patients were followed up 2 years after the revision surgery.Results
Of the 42 patient subjects, 7 showed nonunion. Four of them did not show low back pain; whereas 3 showed moderate or severe low back pain. These 3 patients showed pain reduction after injection of bupivacaine into their nonunion disc space and underwent additional posterior fixation. They showed bony union and pain relief 2 years after the revision surgery.Conclusion
Injection of bupivacaine into the nonunion disc space after ALIF surgery for discogenic low back pain is useful for diagnosis of the origin of pain. 相似文献565.
Kensuke Yoshino Miyako Suzuki Yuya Kawarai Yoshihiro Sakuma Gen Inoue Sumihisa Orita Kazuyo Yamauchi Yasuchika Aoki Tetsuhiro Ishikawa Masayuki Miyagi Hiroto Kamoda Gou Kubota Yasuhiro Oikawa Kazuhide Inage Takeshi Sainoh Jun Sato Junichi Nakamura Tomoaki Toyone Kazuhisa Takahashi Seiji Ohtori 《Yonsei medical journal》2014,55(6):1600-1605