全文获取类型
收费全文 | 6927篇 |
免费 | 396篇 |
国内免费 | 26篇 |
专业分类
耳鼻咽喉 | 51篇 |
儿科学 | 104篇 |
妇产科学 | 117篇 |
基础医学 | 986篇 |
口腔科学 | 156篇 |
临床医学 | 573篇 |
内科学 | 2097篇 |
皮肤病学 | 132篇 |
神经病学 | 588篇 |
特种医学 | 161篇 |
外科学 | 961篇 |
综合类 | 63篇 |
一般理论 | 1篇 |
预防医学 | 483篇 |
眼科学 | 168篇 |
药学 | 415篇 |
中国医学 | 10篇 |
肿瘤学 | 283篇 |
出版年
2023年 | 40篇 |
2022年 | 96篇 |
2021年 | 253篇 |
2020年 | 114篇 |
2019年 | 172篇 |
2018年 | 244篇 |
2017年 | 121篇 |
2016年 | 204篇 |
2015年 | 187篇 |
2014年 | 280篇 |
2013年 | 336篇 |
2012年 | 527篇 |
2011年 | 555篇 |
2010年 | 335篇 |
2009年 | 286篇 |
2008年 | 439篇 |
2007年 | 499篇 |
2006年 | 480篇 |
2005年 | 399篇 |
2004年 | 400篇 |
2003年 | 327篇 |
2002年 | 331篇 |
2001年 | 53篇 |
2000年 | 47篇 |
1999年 | 49篇 |
1998年 | 61篇 |
1997年 | 49篇 |
1996年 | 39篇 |
1995年 | 32篇 |
1994年 | 29篇 |
1993年 | 41篇 |
1992年 | 34篇 |
1991年 | 23篇 |
1990年 | 13篇 |
1989年 | 12篇 |
1988年 | 19篇 |
1987年 | 9篇 |
1986年 | 8篇 |
1984年 | 19篇 |
1983年 | 20篇 |
1982年 | 20篇 |
1981年 | 24篇 |
1980年 | 13篇 |
1979年 | 6篇 |
1978年 | 8篇 |
1977年 | 16篇 |
1976年 | 10篇 |
1974年 | 12篇 |
1970年 | 6篇 |
1969年 | 7篇 |
排序方式: 共有7349条查询结果,搜索用时 15 毫秒
81.
Antonio S. Salinas Sánchez Jesús Cifuentes Tebar Miguel Segura Martín José M. Giménez Bachs María J. Donate Moreno Héctor Pastor Navarro Julio A. Virseda Rodríguez 《American journal of transplantation》2005,5(8):2074-2077
Ureteral herniation is a rare entity. We report the first case of extraperitoneal ureteral herniation in a pediatric en bloc renal graft causing obstructive uropathy. A 70-year-old, obese patient with an en bloc renal transplant was found to have ureterohydronephrosis in the right renal graft on magnetic resonance imaging. Nephrostomy with insertion of a double-J catheter confirmed the presence of a ureteral loop within the inguinal tract. Surgery confirmed herniation of the ureter through the internal inguinal ring, crossing over the spermatic cord. We performed release, resection, ureteral reimplantation and hernioplasty. Four months later, renal function was normal and urinary tract dilation had diminished. This case illustrates an unusual cause of obstructive uropathy in a transplanted kidney. Apart from obesity, two other factors may have contributed to its development: presence of a redundant ureter, and the fact that the ureter had been placed over, rather than under, the spermatic cord. 相似文献
82.
Pedro Popoutchi Carlos Renato dos Reis Lemos Julio César Rosa E Silva Ant?nio Alberto Nogueira Omar Feres José Joaquim Ribeiro da Rocha 《Revista paulista de medicina》2008,126(3):190-193
CONTEXT: Endometriosis is characterized by the presence of endometrial tissue outside the uterine cavity, which is commonly detected in gynecological practice but rarely reported as a coloproctological disorder. The objective of the present report was to discuss a rare case of postmenopausal intestinal endometriosis simulating a malignant lesion, following a review of the literature. CASE REPORT: A 74-year-old woman with complaints of hematochezia and tenesmus of two months' duration accompanied by liquid feces and pelvic pain, but with no other gastrointestinal or gynecological complaints, was referred to our service. She had been menopausal for 22 years, with no hormone replacement treatment, and had undergone panhysterectomy three years before the referral to us, due to endometrial thickening and a right adnexal cyst. Five months before this referral, she had undergone laparotomy due to acute obstructive abdomen, which revealed a tumor mass involving the small bowel. Anatomopathological examination of the enterectomy suggested a hypothesis of intestinal endometriosis. A proctological examination was normal. Computed tomography of the pelvis revealed thickening of the rectosigmoid transition and colonoscopy revealed friable tumor formation in the rectum. A biopsy of the lesion revealed mucosal fragments of endometrial type, which led to a review of the previous anatomopathological examination. The patient underwent rectosigmoidectomy with protective transversotomy, with a good postoperative course, and anatomical examination confirmed the intestinal endometriosis. The patient subsequently suffered a stenosing recurrence of the lesion and has undergone colostomy since then. 相似文献
83.
Laura Pérez-Egido María Antonia García-Casillas Isabel Simal María Fanjul Agustin Cañizo Julio A. Cerdá Beatriz Fernandez Manuel de la Torre Javier Ordoñez Juan Carlos de Agustin 《Journal of pediatric surgery》2019,54(4):693-695
Introduction
New digital thoracic drainage systems allow an objective measurement of air leakage. They have proven their usefulness in the postoperative thoracic surgery in adults, but there is little experience with its use in the pediatric population. The objective of our study is to analyze their safety and effectiveness in the postoperative period of the pediatric patients.Method
A prospective consecutive observational study was done. All patients submitted to pulmonary resection between 2011 and 2017 and in whom digital thoracic drainage system was used (Thopaz Chest Drain System, Medela, Switzerland) were prospectively enrolled in this study. We analyzed variables: duration of chest tube (CT), days of hospitalization and radiographs in the immediate postoperative period related to the presence of CT. This group was compared with a historical cohort of patients (from 2011 to 2015) with a pulmonary resection in whom the traditional thoracic drainage was used. For the statistical analysis, the Mann–Whitney U-Test was used for independent samples.Result
Twenty-six patients were included, Digital drainage system was used in13 patients and traditional drainage was used in 13 patients. The median age was 18?months (12?days-14?years). The mean number of days with the chest tube was 1.69?±?0.6 in digital drainage group versus 5.38?±?4?days in traditional drainage group (p?<?0.05) The mean number of postoperative radiographs was 2.8?±?1.1 in digital drainage group versus 6.23?±?5.2 radiographs in traditional drainage group (p?<?0.05). The average hospital stay in digital drainage group was 5.69?±?2.7?days versus 7?±?4.7?days in the traditional drainage group (p?>?0.05). No complications related to the use of digital drainage group were registered.Conclusion
The digital thoracic drainage systems provide an objective measurement of air leakage, allowing early chest tube removal and decreasing the number of radiographs performed postoperatively. Its use in the pediatric population appears to be safe and potentially beneficial.Level of evidence
II. 相似文献84.
Francisco-Javier Roldán M.D. Jesús Vargas-Barrón M.D. F.A.C.C. Marlon Aguirre-Espìnosa M.D. Ángel Romero-Cárdenas M.D. Clara Vázquez-Antona M.D. Julio Erdmenger-Orellana M.D. José-Emilio Exaire M.D. ‡ Marco-Antonio Martínez-Ríos M.D. F.A.C.C. † 《Echocardiography (Mount Kisco, N.Y.)》2009,26(5):504-507
Subepicardial aneurysms (SEA) are an infrequent and serious form of subacute cardiac rupture complicating myocardial infarction. An early diagnosis and surgical repair may be life saving. SEA comprise an abrupt interruption of the myocardium, with a narrow neck and thin wall containing only the epicardium. It may progress to fatal cardiorrhexis. We describe the echocardiographic evolution of this type of cardiac rupture and the contribution of contrast-enhanced echocardiography. A possible pathophysiological mechanism is proposed. 相似文献
85.
All Patients With the T(11; 16)(q23; p13.3) That Involves MLL and CBP Have Treatment-Related Hematologic Disorders 总被引:14,自引:0,他引:14
86.
Nahum Méndez‐Sánchez Daniel Zamora‐Valdés José A. Flores‐Rangel Julio A. Pérez‐Sosa Francisco Vásquez‐Fernández Jezer I. Lezama‐Mora Genaro Vázquez‐Elizondo Guadalupe Ponciano‐Rodríguez Martha H. Ramos Misael Uribe 《Liver international》2008,28(3):402-406
Background/Aims: Gallstone disease (GD) and cardiovascular disease (CD) are common diseases worldwide with considerable economical impact and they are strongly associated. Carotid atherosclerosis is an excellent marker of risk for CD like stroke and myocardial infarction. The aim of this study was to assess the association between gallstones and carotid atherosclerosis. Methods: A cross‐sectional study was conducted. We evaluated subjects with ultrasonographical evidence of GD and asymptomatic subjects without such evidence. Anthropometric, clinical and biochemical variables were collected. The Metabolic syndrome was evaluated using adult treatment panel III criteria. Carotid artery intima–media thickness (CIMT) was determined by a standard ultrasound protocol. Insulin‐like growth factor‐1 (IGF‐1) serum levels were measured in all subjects. Results: We studied 191 subjects: 62 subjects with GD (53.2% males) and 129 asymptomatic subjects without GD (65.9% males). Subjects with GD exhibited a higher body mass index, body fat percent, insulin serum levels and CIMT (P<0.05 for all). The prevalence of GD was higher in subjects with a CIMT>0.75 independently of other factors [odds ratio (OR) 2.12, 95% confidence interval (CI) 1.04–4.34; P=0.039], and for every 0.1 mm increase in CIMT the independent probability to be a case of GD increased by a factor of 1.25 (95% CI 1.02–1.53; P=0.027). IGF‐1 levels did not differ among groups. Conclusions: Subjects with GD exhibit greater carotid atherosclerosis, and therefore have a higher risk for stroke and myocardial infarction. 相似文献
87.
Seijo Ríos S Lariño Noia J Iglesias García J Lozano León A Domínguez Muñoz JE 《Gastroenterologia y hepatologia》2008,31(2):92-97
Primary cystic pancreatic neoplasms are rare tumors, with an approximate prevalence of 10% of cystic pancreatic lesions. Most of these lesions correspond to mucinous cystic neoplasm, serous cystoadenoma and intraductal papillary mucinous tumor (IPMT). IPMT is characterized by diffuse dilatation of the main pancreatic duct and/or side branches with inner defects related to mucin or tumor, or mucin extrusion from a patent ampulla. IPMT has a low potential for malignancy, with a low growth rate, a low rate of metastatic spread and postsurgical recurrence. Over the last few years, major advances have been made in the diagnostic and therapeutic management of this tumor. 相似文献
88.
Sonia Gutiérrez Silvia Guillemi Natalie Jahnke Valentina Montessori P Richard Harrigan Julio S G Montaner 《Clinical infectious diseases》2008,46(3):e28-e30
We summarize the clinical history and laboratory results following the introduction of tenofovir among 6 patients coinfected with human immunodeficiency virus (HIV) and hepatitis B virus (HBV) who presented with severe liver disease while receiving lamivudine-based highly active antiretroviral therapy. In all cases, the introduction of tenofovir led to a sustained undetectable HBV and HIV loads, with marked clinical and laboratory improvement in liver function. We provide supporting evidence for the role of tenofovir in the management of advanced HBV infection in HIV-positive patients after the development of lamivudine resistance. 相似文献
89.
90.