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91.
Influence of a high-fat diet on gut microbiota, intestinal permeability and metabolic endotoxaemia 总被引:2,自引:0,他引:2
Moreira AP Texeira TF Ferreira AB do Carmo Gouveia Peluzio M de Cássia Gonçalves Alfenas R 《The British journal of nutrition》2012,108(5):801-809
Lipopolysaccharide (LPS) may play an important role in chronic diseases through the activation of inflammatory responses. The type of diet consumed is of major concern for the prevention and treatment of these diseases. Evidence from animal and human studies has shown that LPS can diffuse from the gut to the circulatory system in response to the intake of high amounts of fat. The method by which LPS move into the circulatory system is either through direct diffusion due to intestinal paracellular permeability or through absorption by enterocytes during chylomicron secretion. Considering the impact of metabolic diseases on public health and the association between these diseases and the levels of LPS in the circulatory system, this review will mainly discuss the current knowledge about high-fat diets and subclinical inflammation. It will also describe the new evidence that correlates gut microbiota, intestinal permeability and alkaline phosphatase activity with increased blood LPS levels and the biological effects of this increase, such as insulin resistance. Although the majority of the studies published so far have assessed the effects of dietary fat, additional studies are necessary to deepen the understanding of how the amount, the quality and the structure of the fat may affect endotoxaemia. The potential of food combinations to reduce the negative effects of fat intake should also be considered in future studies. In these studies, the effects of flavonoids, prebiotics and probiotics on endotoxaemia should be investigated. Thus, it is essential to identify dietetic strategies capable of minimising endotoxaemia and its postprandial inflammatory effects. 相似文献
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Bruno Guedes Baldi Alexandre Todorovic Fabro Andreia Craveiro Franco Marília Helena C Machado Robson Aparecido Prudente Estefnia Thom Franco Sergio Ribeiro Marrone Simone Alves do Vale Talita Jacon Cezare Marcelo Padovani de Toledo Moraes Eloara Vieira Machado Ferreira Andr Luis Pereira Albuquerque Marcio Valente Yamada Sawamura Suzana Erico Tanni 《Jornal brasileiro de pneumologia》2022,48(3)
94.
Vinicius Rossa Luanne Ester Monteiro Ferreira Sancler da Costa Vasconcelos Eric Thomas Tai Shimabukuro Vinicius Gomes da Costa Madriaga Anna Paula Carvalho Sibele Berenice Castell Pergher Fernando de Carvalho da Silva Vitor Francisco Ferreira Carlos Adam Conte Junior Thiago de Melo Lima 《RSC advances》2022,12(22):14084
Nanotechnology experienced a great technological advance after the discovery of the graphene family (graphene – Gr, graphene oxide – GO, and reduced graphene oxide-rGO). Based on the excellent properties of these materials, it is possible to develop novel polymeric nanocomposites for several applications in our daily routine. One of the most prominent applications is for food packaging, offering nanocomposites with improved thermal, mechanical, anti-microbial, and barrier properties against gas and water vapor. This paper reviewed food packaging from its inception to the present day, with the development of more resistant and intelligent packaging. Herein, the most common combinations of polymeric matrices (derived from non-renewable and renewable sources) with Gr, GO, and rGO and their typical preparation methods are presented. Besides, the interactions present in these nanocomposites will be discussed in detail, and their final properties will be thoroughly analyzed as a function of the preparation technique and graphene family-matrix combinations.Food packaging based on nanotechnology of polymeric nanocomposites of graphene and graphene oxide results in packaging with better thermal, mechanical, antimicrobial, electrical packaging, moisture barrier and gas properties. 相似文献
95.
Polyethylene glycol fusion associated with antioxidants: A new promise in the treatment of traumatic facial paralysis 下载免费PDF全文
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Edmilson Bastos de Moura Marcelo de Oliveira Maia Monalisa Ghazi Fábio Ferreira Amorim Henrique Marconi Pinhati 《The Brazilian journal of infectious diseases》2012,16(5):479-481
Disseminated strongyloidiasis is a disease with high mortality rate, especially in immunocompromised individuals. Paralytic ileus and intestinal malabsorption are frequent symptoms caused by this severe disease. As there are no licensed parenteral anthelmintic drugs for human use, off-label formulations are often used in the treatment of this disease. In this case report, the use of subcutaneous ivermectin is described as a successful therapy for this life-threatening infection. 相似文献
100.
Marina Dias-Neto Mariana Pintalhão Mariana Ferreira Nuno Lunet 《Nutrition and cancer》2013,65(2):133-147
The understanding of the association between salt intake and precancerous lesions may contribute to clarify the causal relation with gastric cancer. We systematically reviewed 17 articles addressing the association between dietary salt exposure and gastric intestinal metaplasia and conducted meta-analyses for quantitative synthesis (random effects model). Salt exposure was estimated assessing salted/salty food consumption, preference for salted/salty foods, use of table salt, or sodium urinary excretion. Heterogeneity was also large regarding food items evaluated, consumption categories, and data analysis. The combined odds ratio (OR) was 1.68 (95% confidence interval (CI) = 0.98–2.90; I2 = 55.4%) for the association between salted/salty meat and intestinal metaplasia (4 studies) and the OR was 1.53 (95% CI = 0.72–3.24; I2 = 76.8%) for salt preference. There was a positive, nonstatistically significant association between intestinal metaplasia and urinary sodium excretion. The heterogeneity of methodological options and results preclude quantitative synthesis or its proper interpretation, even if the available evidence may suggest a positive association between salt and intestinal metaplasia. 相似文献