全文获取类型
收费全文 | 173011篇 |
免费 | 13229篇 |
国内免费 | 658篇 |
专业分类
耳鼻咽喉 | 1990篇 |
儿科学 | 4606篇 |
妇产科学 | 3528篇 |
基础医学 | 22578篇 |
口腔科学 | 3618篇 |
临床医学 | 17782篇 |
内科学 | 34521篇 |
皮肤病学 | 2251篇 |
神经病学 | 15191篇 |
特种医学 | 6836篇 |
外国民族医学 | 3篇 |
外科学 | 26511篇 |
综合类 | 2729篇 |
现状与发展 | 1篇 |
一般理论 | 222篇 |
预防医学 | 17002篇 |
眼科学 | 3838篇 |
药学 | 12372篇 |
2篇 | |
中国医学 | 224篇 |
肿瘤学 | 11093篇 |
出版年
2023年 | 872篇 |
2022年 | 1346篇 |
2021年 | 3228篇 |
2020年 | 1866篇 |
2019年 | 3057篇 |
2018年 | 3613篇 |
2017年 | 2654篇 |
2016年 | 2827篇 |
2015年 | 3357篇 |
2014年 | 4895篇 |
2013年 | 7332篇 |
2012年 | 10750篇 |
2011年 | 11259篇 |
2010年 | 6293篇 |
2009年 | 5721篇 |
2008年 | 9972篇 |
2007年 | 10652篇 |
2006年 | 10248篇 |
2005年 | 10306篇 |
2004年 | 9919篇 |
2003年 | 9330篇 |
2002年 | 9025篇 |
2001年 | 2495篇 |
2000年 | 2288篇 |
1999年 | 2464篇 |
1998年 | 2071篇 |
1997年 | 1683篇 |
1996年 | 1613篇 |
1995年 | 1523篇 |
1994年 | 1365篇 |
1993年 | 1330篇 |
1992年 | 1664篇 |
1991年 | 1663篇 |
1990年 | 1530篇 |
1989年 | 1413篇 |
1988年 | 1457篇 |
1987年 | 1397篇 |
1986年 | 1362篇 |
1985年 | 1495篇 |
1984年 | 1442篇 |
1983年 | 1288篇 |
1982年 | 1406篇 |
1981年 | 1438篇 |
1980年 | 1230篇 |
1979年 | 1100篇 |
1978年 | 1017篇 |
1977年 | 862篇 |
1976年 | 796篇 |
1975年 | 722篇 |
1974年 | 760篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
81.
82.
James Orbinski 《Canadian Medical Association journal》2002,167(5):481-482
83.
84.
Phase I study of high-dose cytosine arabinoside and etoposide in patients with advanced malignancies
Bayard L. Powell Hyman B. Muss Robert L. Capizzi Mary E. Caponera Douglas R. White Patricia J. Zekan James N. Atkins Don V. Jackson Jr. Frederick Richards II John B. Craig Julia M. Cruz Charles L. Spurr 《Cancer chemotherapy and pharmacology》1987,19(3):250-252
Summary Cytosine arabinsodie (ara-C) and etoposide (VP-16) display synergy in the laboratory. Twenty-six patients participated in a phase I study of high-dose ara-C in combination with VP-16. The dose of VP-16 was held constant at 50 mg/m2 as an intermittent infusion over 33 h; escalating doses of ara-C were given as infusions during hours 9–12 and 21–24. Myelosuppression was the dose-limiting toxicity and occurred with doses considerably less than those expected from studies of the two drugs as single agents. The suggested initial doses for phase II trials with this schedule are 750 mg/m2×2 doses of ara-C and 50 mg/m2 of VP-16. Nonhematologic toxicity was minimal; therefore, further dose escalation is feasible in patients in whom myelosuppression is acceptable.Supported in part by grants from the National Cancer Institute (CA-12197 and CA-09422) and the American Cancer Society CF-85-182 相似文献
85.
Michael S Benninger Peter C Appelbaum James C Denneny David J Osguthorpe James A Stankiewicz 《Otolaryngology--head and neck surgery》2002,127(1):7-12
OBJECTIVE: Traditional assessments of the microbial flora associated with acute bacterial rhinosinusitis have relied on maxillary sinus punctures (taps) and culture. These taps are now considered the gold standard for obtaining cultures and are used as the method of identifying bacterial pathogens in antimicrobial trials. Maxillary sinus taps are limited by discomfort to the patients and technical concerns. Because of these factors, the standard of performing taps has limited antibiotic trials and microbial surveillance. Alternatives to maxillary sinus taps have been explored. STUDY DESIGN: We conducted a retrospective, systematic review of the literature from 1950 to 2000 of articles comparing culture techniques in the nose and paranasal sinuses for acute bacterial rhinosinusitis. RESULTS: Nasal cultures have poor correlation to maxillary sinus cultures, whereas there is 60% to 85% concordance between endoscopically guided middle meatal cultures and maxillary sinus cultures. These studies, however, are all limited by small sample sizes and therefore are inadequate to make any concrete recommendations regarding the relative role of endoscopically guided middle meatal cultures as a formal method of pathogen identification in acute bacterial rhinosinusitis. CONCLUSION: A formal prospective study with sufficient sample size to assess the concordance between the microbial flora of the maxillary sinus punctures and middle meatal cultures in acute rhinosinusitis is recommended. 相似文献
86.
M B Taylor 《Postgraduate medicine》1991,89(8):40-2, 45-7
The spectrum of acne vulgaris is wide, ranging from minor comedones to devastating nodules and cysts. Appropriate therapy requires an understanding of the various types of lesions, their pathophysiology, and the rationale for treatment. Good patient rapport and communication are important, and close follow-up is necessary until the treatment regimen has stabilized. Timely referral to a dermatologist is essential when therapy is not effective. With effort, the treatment of acne can be quite rewarding for both patient and physician. 相似文献
87.
David C. Cone MD Susan M. Nedza MD MBA James J. Augustine MD Steven J. Davidson MD MBA 《Academic emergency medicine》2002,9(11):1085-1090
This paper reports the proceedings of the discussion panel assigned to look at clinical aspects of quality in emergency medicine. One of the seven stated objectives of the Academic Emergency Medicine consensus conference on quality in emergency medicine was to educate emergency physicians regarding quality measures and quality improvement as essential aspects of the practice of emergency medicine. Another topic of interest was a discussion of the value of information technology in facilitating quality care in the clinical practice of emergency medicine. It is important to note that this is not intended to be a comprehensive review of this extensive topic, but instead is designed to report the discussion that occurred at this session of the consensus conference. 相似文献
88.
32nd Annual Meeting of the Scandinavian Society for Psychopharmacology Copenhagen, Denmark April 10–12, 1991 Abstracts 相似文献
89.
90.
Patrick J. Taylor 《Canadian Medical Association journal》1991,145(10):1362-1363