全文获取类型
收费全文 | 28796篇 |
免费 | 1854篇 |
国内免费 | 87篇 |
专业分类
耳鼻咽喉 | 186篇 |
儿科学 | 929篇 |
妇产科学 | 792篇 |
基础医学 | 4489篇 |
口腔科学 | 355篇 |
临床医学 | 2575篇 |
内科学 | 6510篇 |
皮肤病学 | 402篇 |
神经病学 | 2779篇 |
特种医学 | 981篇 |
外国民族医学 | 5篇 |
外科学 | 4608篇 |
综合类 | 289篇 |
一般理论 | 10篇 |
预防医学 | 1714篇 |
眼科学 | 293篇 |
药学 | 1657篇 |
中国医学 | 33篇 |
肿瘤学 | 2130篇 |
出版年
2023年 | 100篇 |
2022年 | 177篇 |
2021年 | 401篇 |
2020年 | 231篇 |
2019年 | 404篇 |
2018年 | 518篇 |
2017年 | 355篇 |
2016年 | 417篇 |
2015年 | 540篇 |
2014年 | 719篇 |
2013年 | 1002篇 |
2012年 | 1547篇 |
2011年 | 1727篇 |
2010年 | 1060篇 |
2009年 | 1018篇 |
2008年 | 1632篇 |
2007年 | 1644篇 |
2006年 | 1661篇 |
2005年 | 1792篇 |
2004年 | 1566篇 |
2003年 | 1522篇 |
2002年 | 1546篇 |
2001年 | 593篇 |
2000年 | 614篇 |
1999年 | 545篇 |
1998年 | 422篇 |
1997年 | 373篇 |
1996年 | 329篇 |
1995年 | 306篇 |
1994年 | 286篇 |
1993年 | 268篇 |
1992年 | 428篇 |
1991年 | 366篇 |
1990年 | 339篇 |
1989年 | 362篇 |
1988年 | 325篇 |
1987年 | 308篇 |
1986年 | 282篇 |
1985年 | 273篇 |
1984年 | 257篇 |
1983年 | 210篇 |
1982年 | 172篇 |
1981年 | 187篇 |
1980年 | 108篇 |
1979年 | 193篇 |
1978年 | 146篇 |
1976年 | 105篇 |
1975年 | 103篇 |
1974年 | 125篇 |
1973年 | 115篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
91.
E M Boyczuk W Synan J Berger B D Gold 《Oral surgery, oral medicine, and oral pathology》1987,64(5):539-540
A case of dislodgement of a submandibular sialolith into the oropharynx during nasal intubation is presented. The deleterious effect of the patient aspirating the stone into the lungs was averted by the taking of a lateral skull radiograph and localization and removal of the sialolith. 相似文献
92.
Potential advantages and disadvantages of dual-career relationships are identified, and strategies for addressing common issues encountered by dual-career couples are presented. With regard to career issues, clarification of expectations and discussion between partners regarding career commitment, job selection and mobility, and maintenance of professional identity is emphasized. Benefits of dual-career relationships include shared occupational interests, financial rewards, and respect for each partner's professional expertise. Strategies for managing domestic responsibilities include modifying standards, setting priorities, and distributing tasks evenly among family members. Pharmacist couples who are parents have chosen several routes in managing child-care issues, including postponing childbearing until each adult's career is established, decreasing one partner's career involvement, and hiring community or in-home caretakers. Sharing equally in child care can help prevent an excessive workload for one parent. Progressive family-oriented employment practices may also aid dual-career couples with children. Striking a balance between career and family is identified as perhaps the most challenging task facing the dual-career couple; time distribution must be adjusted according to the couple's priorities. Identifying realistic priorities, negotiating honestly regarding attainment of mutual and individual goals, and maintaining flexibility are key in achieving success in the professional and private lives of two-pharmacist couples. 相似文献
93.
94.
A shortened latency of rapid eye movement (REM) sleep is one of the most stable biological abnormalities described in depressive patients. According to the reciprocal interaction model of non-REM and REM sleep regulation, REM sleep disinhibition at the beginning of the night in depression is a consequence of heightened central nervous system cholinergic transmitter activity in relation to aminergic transmitter activity. A recent study has indicated that muscarinic supersensitivity, rather than quantitatively enhanced cholinergic activity, may be the primary cause of REM sleep abnormalities in depression. The present study tested this hypothesis by treating healthy volunteers for 3 days with a cholinergic antagonist (scopolamine) in the morning, in an effort to induce muscarinic receptor supersensitivity. On the last day of scopolamine administration, RS 86, an orally active cholinergic agonist, was administered before bedtime to test whether this procedure would induce sleep onset REM periods. Whereas scopolamine treatment tended to advance REM sleep and to heighten REM density in healthy controls in comparison to NaCl administration, the additional cholinergic stimulation did not provoke further REM sleep disinhibition. This result underlines the need to take a hypofunction of aminergic transmitter systems into account in attempts to explain the pronounced advance of REM sleep typically seen in depressives. 相似文献
95.
K L Davis L E Hollister A A Mathé B M Davis A B Rothpearl K F Faull J Y Hsieh J D Barchas P A Berger 《The American journal of psychiatry》1981,138(12):1555-1562
The authors performed dexamethasone suppression tests (DST), TRH infusions, 72-hour urine collections, and lumbar punctures on a group of male depressed patients. Approximately 60% of the patients were DST positive and 33% had a blunted TSH response. Two biologic variables, the 8 a.m. postdexamethasone cortisol and the postprobenecid CSF 5-hydroxyindoleacetic acid (5-HIAA), accounted for over half of the variance in the behavioral measure, the Hamilton score. Plasma cortisol elevation was associated with high 3-methoxy-4-hydroxyphenyl glycol (MHPG) excretion; TSH blunting was associated with low urinary MHPG excretion. Comprehensive biologic measures showed certain significant interrelationships and correlations with the severity of depression. 相似文献
96.
Helen E. Savaki Jean-Antoine Girault Umberto Spampinato Ngog-An Truong Jacques Glowinski Marie-Jo Besson 《Brain research bulletin》1986,16(2)
The release of newly synthesized 3H-dopamine (3H-DA) was measured in the rat striatum superfused, through a push-pull cannula, with a physiological medium enriched in 3H-tyrosine. The level of spontaneous 3H-DA release was dependent on the topographical localisation of the cannula in the striatum (anterior parts displayed higher levels than posterior ones) and on the anesthetic state (halothane anesthetized rats demonstrated higher levels than awake ones). Inhibition of DA inactivation processes by local application of benztropine (a DA reuptake inhibitor, 10−6 M) or by IV administration of pargyline (a MAO inhibitor, 100 mg/kg) enhanced the detectable outflow of 3H-DA from the striatum in both halothane anesthetized and awake rats. Local application of D-amphetamine (10−5 M) or acetylcholine (5 × 10−5 M) in the presence of eserine (5 × 10−5 M) evoked respectively a fivefold and a 30% increase in spontaneous 3H-DA release in halothane anesthetized rats. Inhibition of the firing of dopaminergic neurons by IV injection of gamma-hydroxybutyrate (400 mg/kg) produced a 30% decrease in striatal 3H-DA release. The present results demonstrate that the push-pull cannula method is suitable for the study of DA release in both the anesthetized and the awake rat. 相似文献
97.
J Schachter A Pomeranz I Berger B Wolach 《The International journal of pediatric nephrology》1987,8(4):211-214
We report 4 cases of children who developed lobar pneumonia and subsequently acute glomerulonephritis, all within a period of six weeks. In one case streptococcus pneumonia type 5 was isolated, a strain not previously described in the literature as being nephritogenic. 相似文献
98.
Clinical practice guidelines for the care and treatment of breast cancer: Mastectomy or lumpectomy? The choice of operation for clinical stages I and II breast cancer (summary of the 2002 update) 总被引:1,自引:0,他引:1 下载免费PDF全文
99.
M Ingram S Jacques D B Freshwater G B Techy C H Shelden J T Helsper 《Archives of surgery (Chicago, Ill. : 1960)》1987,122(12):1483-1486
We present the preliminary results of a phase I trial of adoptive immunotherapy for recurrent or residual malignant glioma. The protocol is based on surgical debulking followed by implantation into the tumor bed of autologous lymphocytes that have been stimulated with phytohemagglutinin-P and then cultured in vitro in the presence of interleukin 2. Fifty-five patients with a mean Karnofsky rating of 64 were treated between February 1985 and March 1987. No significant toxicity was associated with the immunotherapy. Fifty patients had a positive initial response to therapy, nine patients had early recurrence (two to four months after treatment), and 22 patients died. We comment on major differences between the protocol described and other immunotherapy protocols. 相似文献
100.