Pseudotumor in the Mallory-Weiss Syndrome

A Mallory-Weiss laceration with endoscopic and radiologic features of a submucosal tumor is described. Repeat examination showed complete resolution of the lesion.     

Gastric Carcinoid Endoscopically Simulating Leiomyoma

A 23-year old black man is presented who had a gastric carcinoid which clinically, endoscopically and radiographically simulated leiomyoma. The gastroscopic findings and clinical features of gastric carcinoids are reviewed.     

Induction in Rabbits of Activity Against Human Blood Thromboplastin

Rabbits were injected with sedimented human blood thromboplastin, andtwo animals developed serum activity against human blood thromboplastinin significant excess over naturally occurring inhibitor. This antithromboplasticactivity was specific against human reagent, failed to affect thromboplastinprecursors and had no activity against tissue thromboplastin.

     

Reticuloendothelial Clearance of Blood Thromboplastin by Rats

Data have been presented suggesting that blood thromboplastin givenintravenously to rats is cleared by the reticuloendothelial system. (1) Thereagent given into the jugular vein or aorta caused profound defibrination,whereas injection into the portal circulation caused a milder reaction. Thesedifferences were obtained irrespective of the source of phosphatide in thethromboplastin generation mixture. (2) Reticuloendothelial blockade reducedthe protective effect of portal administration. (3) Radioactive blood thromboplastin given intravenously was rapidly cleared from the blood, and showedan organ distribution resembling that of agents known to be removed byreticuloendothelial cells. (4) Injection of the blood thromboplastin during acarbon clearance caused depression of the carbon disappearance slope.

Submitted on August 29, 1960 Accepted on October 19, 1960     

Randomized Comparison of Efficacy of Cooled Tip Catheter Ablation of Atrial Flutter: Anatomic Versus Electrophysiological Complete Isthmus Block

There is a subset of patients with failed ablation of the cavotricuspid isthmus (CTI) using standard catheters and with 10% of the patients having recurrences. The purpose of this study was to compare the cooled and standard ablation with regard to acute successful electrophysiological achievement of bidirectional isthmus block and the subacute anatomic characteristics of the lesions. This randomized, experimental study compares the effects of ablation on the isthmus using a cooled catheter with those of a standard ablation catheter in 16 pigs. In 12 animals, CTI block was achieved after ablation (8/8 cooled and 4/8 standard). In two animals, it was not possible to achieve complete isthmus block and two had persistent slow conduction (all four using the standard catheter). After 1 week, the animals were slaughtered. The size of the lesion was greater with the irrigated tip catheters. Transmural lesions were found in 14 animals. A complete line of anatomic isthmus block was not documented after thefirst line in six animals, four with the standard and two with the cooled catheter. A conduction block was never present across gaps > or = 5 mm. In conclusion cooled catheters achieved a complete line of electrophysiological and anatomical block in a significantly higher percentage than the standard catheters.