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111.
Changhoon Park Hwi Won Seo Kiwon Han Chanhee Chae 《Clinical and Vaccine Immunology : CVI》2014,21(3):399-406
Under Korean field conditions, coinfection with porcine circovirus type 2 (PCV2) and porcine reproductive and respiratory syndrome virus (PRRSV) is most commonly observed in porcine respiratory disease complex (PRDC). Despite the wide use of PCV2 vaccination, PRDC remains a serious respiratory problem. Thus, the objective of this study was to determine and compare the efficacy of 4 one-dose PCV2 vaccines on 3-week-old pigs with an experimental PCV2-PRRSV challenge at 17 weeks postvaccination. Regardless of which commercial PCV2 vaccine was used, the vaccination of piglets at 3 weeks of age was efficacious against cochallenge of PCV2 and PRRSV, on the basis of growth performance and PCV2-associated lesions. However, the inactivated chimeric PCV1-2 and the PCV2 vaccines induced higher PCV2-specific neutralizing antibody (NA) titers and PCV2-specific gamma interferon-secreting cells and lower PCV2 viremia levels than the two PCV2 subunit vaccines. The vaccination of piglets against PCV2 at 3 weeks of age was effective in reducing PCV2 viremia and PCV2-associated lesions during the finishing period, which is an age at which pigs are frequently affected by PRDC caused by coinfection with PCV2 and PRRSV under Korean field conditions. 相似文献
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ABSTRACTIntraocular lens (IOL) implantation in pediatric eyes with insufficient capsular support is challenging and there are multiple IOL options. These include placement of an IOL within the capsular bag with a capsular tension ring, a scleral-fixated posterior-chamber IOL (PCIOL) with or without capsular tension segment or ring, an intra-scleral fixated IOL, an iris-sutured PCIOL, or an anterior chamber iris-fixated IOL. We reviewed 48 articles and 1 published abstract describing the surgical techniques, complications and visual outcomes of different IOL options in the management of aphakic pediatric eyes with insufficient capsular support. The present review found that the visual acuity outcomes of various IOLs are comparable. Furthermore, each IOL design and surgical technique has different rates of serious complications, including IOL dislocation or decentration, intraocular hemorrhage, glaucoma, endothelial cell loss, and endophthalmitis. An understanding of the risks and benefits of different IOL designs is important for counseling patients and families. 相似文献
114.
辛夷挥发油的抗炎、抗过敏作用 总被引:6,自引:0,他引:6
辛夷挥发油腹腔注射(50,100mg/kg)能明显对抗二甲苯所致小鼠耳廓肿和蛋清所致的大鼠足跖肿。辛夷挥发油(20,30,40mg/ml)能对抗SRS-A、HA所致的豚鼠离体回肠的收缩作用,并能对抗致敏豚鼠回肠的过敏性收缩,这证明辛夷挥发油具有明显的抗炎、抗过敏作用。 相似文献
115.
This study aims to provide information about the prevalence of refractive errors among Chinese school children in Hong Kong, and its relationship with the optical components of the eye. Subjective refraction, corneal curvatures and ocular biometry were performed on 383 school children from age six to 17 years. The prevalence of myopia increases from 30 per cent at age six to seven to 50 per cent (girls) and 70 per cent (boys) at age 16–17. The mean spherical equivalent refraction gradually changes from plano at age six to seven to -2.00 D of myopia at age 1617. Our results are different from Caucasian data but comparable with those of other studies of Chinese in Asia. The increase in myopia correlates well with the axial length of the eye. Further studies are needed to investigate the cause for the development of myopia. 相似文献
116.
Assessment of congenital heart defects by dynamic three-dimensional echocardiography: methods of data acquisition and clinical potential 总被引:1,自引:0,他引:1
To evaluate the use of three-dimensional (3D) echocardiography in the diagnosis of congenital heart defects, we studied 238 patients aged 3 days to 19 years (mean 4.3 years) with normal hearts ( n = 13) or a variety of congenital heart defects (n = 225) Three different modalities of data acquisition suitable for reconstruction were applied For parallel scanning, the transducer is held in a 6-cm long scan frame and then moved over the thorax, or in the subcostal position, by a stepper motor using 0.5-mm steps with acquisition of perpendicular parallel images of the heart For rotational scanning, the transducer is rotated at sectors of 2° over a span of 180° For fan-like scanning, the transducer is moved in an arc 45° each way from its vertical axis Movement of the transducer is computer-controlled and performed with electrocardiography and respiratory gating Between 80 and 120 slices of the heart are thus obtained, which form the dataset This dataset can then be "sectioned" in any desired plane, thus permitting generation of views simulating intraoperative perspectives Ventricular septal defects and atrioventricular valves can be displayed as viewed via the atrium Muscular ventricular septal defects can be viewed as seen through a ventriculotomy Obstruction in the left ventricular outflow tract can be viewed as via an aortotomy, and so on We conclude that this new imaging modality has a vast potential and may facilitate planning of intracranial surgery. 相似文献
117.
Estrogen has received considerable attention recently as a potential therapeutic agent in vascular pathophysiological states such as stroke. The mechanisms by which estrogen influences cerebral arteries are incompletely understood. The present study was to examine the effect of ovariectomy and chronic estrogen or tamoxifen treatment on vascular reactivity in rat posterior communicating cerebral arteries with intact endothelium. Changes in vascular tension were measured by microvessel myograph. Ovariectomy significantly enhanced the constricting responses to endothelin I, but not to phenylephrine. Chronic treatment with estrogen or tamoxifen partially reversed or abolished the effect of ovariectomy. The contraction induced by high K+ solution was also enhanced in the ovariectomized rats and this enhancement was abolished by estrogen or tamoxifen treatment. Ovariectomy potentiated the relaxant response to nicardipine but not NS 1619. Estrogen but not tamoxifen reversed the effect of ovariectomy. The present results indicate that chronic tamoxifen may not act as an antagonist of estrogen, instead, chronic treatment with estrogen and tamoxifen has similar effect in inhibiting the increased vascular tension induced by ovariectomy. This study suggests the influence of physiological level of estrogen on vascular contractility. It is at present unknown what may have caused increased relaxant effect of nicardipine, a L-type Ca2+ channel blocker. More experiments are needed to show the role of endothelium in the altered vascular contractility in the ovariectomized and estrogen-treated rats. (supported by UPGC Direct Grant). 相似文献
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Se Yong Jung Min Seo Kim Han Li Keum Hwa Lee Ai Koyanagi Marco Solmi Andreas Kronbichler Elena Dragioti Kalthoum Tizaoui Sarah Cargnin Salvatore Terrazzino Sung Hwi Hong Ramy Abou Ghayda Nam Kyun Kim Seo Kyoung Chung Louis Jacob JoeElie Salem Dong Keon Yon Seung Won Lee Karel Kostev Ah Young Kim Jo Won Jung Jae Young Choi Jin Soo Shin SoonJung Park Seong Woo Choi Kiwon Ban SungHwan Moon Yun Young Go Jae Il Shin Lee Smith 《CTS Clinical and Translational Science》2022,15(2):501