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81.
We retrospectively reviewed the chart records at the Veterans General
Hospital-Taipei for the period between January 1985 and December 1994 to
examine the temporal relationship between cancers of the lung and upper
aerodigestive tract. A total of 56 patients (54 males, 2 females) with
histocytologically proven double primary cancers, with either lung cancer
or upper aerodigestive tract cancers appearing first, were found. Squamous
cell carcinoma was the most frequent histologic type of lung cancer
(squamous 57%, adenocarcinoma 27%, poorly differentiated carcinoma 9%,
small cell lung cancer 7%). The incidence of lung cancer patients with
upper aerodigestive tract cancer was 0.9% (56/6412). There was no
significant difference in the occurrence of upper aerodigestive tract
cancer between non-small cell and small cell lung cancer (P > 0.05).
However, the incidence of squamous cell lung cancer with upper
aerodigestive tract cancer was higher than that of non-squamous cell lung
cancer (P < 0.05). With regard to the location of lung cancer, the right
lung was more commonly affected than the left (P < 0.001). The locations
of upper aerodigestive tract cancers in these lung cancer patients were as
follows: larynx 24, nasopharynx 11, esophagus 10, hypopharynx 4, pharyngeal
tonsils 2, oral cavity 5. Most upper aerodigestive tract cancers were
diagnosed before lung cancer (36/56, 64%), and lung cancer was diagnosed
within 3 years in more than half of cases after the diagnosis of upper
aerodigestive tract cancer (58.3%). Most lung cancers that preceded upper
aerodigestive tract cancer were at an early stage at diagnosis (stage I 4,
stage Illa 1), whereas the others, appearing either synchronously or after
the diagnosis of upper aerodigestive tract cancer, were mostly at the late
stage. There was no difference in survival between lung cancer patients
with upper aerodigestive tract cancer and those without (P > 0.05).
相似文献
82.
ML Tang XY Liu JW Ren DC Zhang RS Li YM Wen BF Ge 《Surgical and radiologic anatomy : SRA》1993,15(4):259-263
Summary The vascular supply to the distal part of sartorius m. was studied in 37 limbs by dissection under magnification and after black ink and latex injections. The muscle or myocutaneous island flap pedicled on the saphenous artery (SA) is supplied by a retrograde circulation through anastomoses of the SA with the perforating branches of the posterior tibial artery and the medial inferior genicular artery. Three different vascular patterns were defined. Retrograde injection also showed good perfusion of the SA. The flap is useful for covering around the knee, the proximal and middle thirds of the lower leg, and the end of the amputation stump. Raising of the flap has not resulted in any functional or cosmetic defect. Eighteen operations have so far been performed, six using the muscle island flap and twelve using the myocutaneous island flap, and all survived completely.
Le lambeaux en îlot myo-cutané du muscle sartorius
Résumé L'apport artériel pour la partie distale du m. sartorius a été étudié sur 37 membres par dissection sous grossissement et après injection d'encre de Chine et de latex. Le lambeau en îlot, musculaire ou myo-cutané, pédiculé sur l'artère saphène (SA), est vascularisé par une circulation rétrograde à travers les anastomoses de la SA avec les branches perforantes de l'artère tibiale postérieure et l'artère inféro-médiale du genou. Trois schémas vasculaires différents ont été définis. L'injection rétrograde montrait aussi une bonne perfusion de la SA. Le lambeau est utile pour la couverture des régions proches du genou, des tiers proximal et moyen de la jambe et de l'extrémité des moignons d'amputation. La réalisation du lambeau n'a entraîné aucun dommage fonctionnel ou cosmétique. Dix-huit interventions ont été réalisées jusqu'ici, six utilisant le lambeau en îlot musculaire et douze utilisant le lambeau en îlot myocutané, sans aucune complication locale.相似文献
83.
Jessica Hui-Beckman Byung Eui Kim Donald YM Leung 《Allergy, asthma & immunology research》2022,14(1):8
As the incidence of atopic conditions continues to increase, emphasis has been placed on understanding the origin of allergy with hope that prevention measures can be achieved. The perinatal environment is important for this understanding, given that both the immune system and microbiome start forming prenatally. Maternal exposure can greatly impact on fetal health. Additionally, the dysfunctional epithelial barrier is influential in allowing allergens and irritants to penetrate the skin or mucosa, leading to the release of proinflammatory cytokines and mediators to drive type 2 tissue inflammation and the onset of allergy. There are numerous factors related to skin, airway, and gut epithelial barriers dysfunction, and genetic predispositions are also present. Comprehensive birth cohort studies and further mechanistic studies will be keys to understanding the origin of allergy. 相似文献
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88.
康宁克通A治疗白内障术后迟发型急性前葡萄膜炎的临床观察 总被引:3,自引:0,他引:3
李毓敏 《中国现代应用药学》1999,16(4):63-65
目的:报告康宁克通A眼周注射,治疗白内障超声乳化吸出联合硅胶折叠式人工晶体植入术后,并发迟发型前葡萄膜炎的临床疗效总结和病机搪塞。方法:对28例(28眼)患者发病早期,给予本病20mg球结膜下或后Tenon囊下注射一次。 相似文献
89.
Mohammad M Ghahramani Seno Benjamin YM Kwan Ka Ki M Lee-Ng Rainald Moessner Anath C Lionel Christian R Marshall Stephen W Scherer 《BMC medical genetics》2011,12(1):45
Background
Copy number variations (CNVs) can contribute to variable degrees of fitness and/or disease predisposition. Recent studies show that at least 1% of any given genome is copy number variable when compared to the human reference sequence assembly. Homozygous deletions (or CNV nulls) that are found in the normal population are of particular interest because they may serve to define non-essential genes in human biology. 相似文献90.
YY Huang ; SS Yang ; CH Wu ; WS Shih ; CS Huang ; PH Chen ; YM Lin ; CT Shen ; DS Chen 《Transfusion》1994,34(8):661-665
BACKGROUND: Hepatitis C is the major cause of posttransfusion hepatitis. Blood components that are positive for antibody to hepatitis C virus (anti-HCV) can transmit posttransfusion hepatitis. STUDY DESIGN AND METHODS: To investigate the effect on posttransfusion hepatitis of screening blood donors with a second-generation test for anti-HCV, 249 transfusion recipients who underwent cardiovascular surgery were prospectively followed. Six recipients who were positive for anti-HCV before transfusion and 51 subjects with incomplete follow-up were excluded from this study. RESULTS: Eleven (13.8%) of 80 subjects who received unscreened blood had two successive serum alanine aminotransferase levels > 90 U per L. Seven (8.8% of total) developed anti-HCV and HCV RNA and two (2.5% of total) developed IgM antibody to cytomegalovirus (IgM anti-CMV). By contrast, 3 (2.7%) of the 112 subjects who received anti-HCV-screened blood had two successive serum alanine aminotransferase levels > 90 U per L. None of these three developed anti-HCV and HCV RNA, but two (1.8% of total) showed the development of IgM anti-CMV. The study shows that screening for anti- HCV in blood donors with a second-generation test almost abrogated posttransfusion viral hepatitis C. CONCLUSION: After anti-HCV screening, other body fluid-transmitted viruses such as CMV may become important in posttransfusion hepatitis. 相似文献