全文获取类型
收费全文 | 278189篇 |
免费 | 13162篇 |
国内免费 | 1945篇 |
专业分类
耳鼻咽喉 | 3786篇 |
儿科学 | 7650篇 |
妇产科学 | 7596篇 |
基础医学 | 41050篇 |
口腔科学 | 9010篇 |
临床医学 | 18493篇 |
内科学 | 56729篇 |
皮肤病学 | 6843篇 |
神经病学 | 20938篇 |
特种医学 | 7892篇 |
外国民族医学 | 4篇 |
外科学 | 35253篇 |
综合类 | 6046篇 |
一般理论 | 58篇 |
预防医学 | 27608篇 |
眼科学 | 6961篇 |
药学 | 22480篇 |
中国医学 | 1481篇 |
肿瘤学 | 13418篇 |
出版年
2021年 | 3417篇 |
2020年 | 1957篇 |
2019年 | 3854篇 |
2018年 | 6521篇 |
2017年 | 4224篇 |
2016年 | 4229篇 |
2015年 | 4804篇 |
2014年 | 5588篇 |
2013年 | 8134篇 |
2012年 | 13466篇 |
2011年 | 14255篇 |
2010年 | 7463篇 |
2009年 | 5816篇 |
2008年 | 11930篇 |
2007年 | 12778篇 |
2006年 | 12359篇 |
2005年 | 11606篇 |
2004年 | 10828篇 |
2003年 | 10175篇 |
2002年 | 9590篇 |
2001年 | 11320篇 |
2000年 | 12067篇 |
1999年 | 9653篇 |
1998年 | 2575篇 |
1997年 | 1865篇 |
1992年 | 5822篇 |
1991年 | 5647篇 |
1990年 | 5404篇 |
1989年 | 5095篇 |
1988年 | 4902篇 |
1987年 | 4685篇 |
1986年 | 4516篇 |
1985年 | 4303篇 |
1984年 | 2987篇 |
1983年 | 2609篇 |
1982年 | 1420篇 |
1979年 | 2992篇 |
1978年 | 1921篇 |
1977年 | 1711篇 |
1976年 | 1611篇 |
1975年 | 1975篇 |
1974年 | 2396篇 |
1973年 | 2481篇 |
1972年 | 2371篇 |
1971年 | 2242篇 |
1970年 | 2065篇 |
1969年 | 2105篇 |
1968年 | 2066篇 |
1967年 | 1820篇 |
1966年 | 1644篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
91.
S. Regnier Z. Ouagari Z. L. Perez N. Veziris F. Bricaire E. Caumes 《Clinical and experimental dermatology》2009,34(8):e690-e692
We report the case of a patient infected with human immunodeficiency virus who presented with fever and a disseminated papulous eruption, diagnosed as cutaneous miliary tuberculosis. The diagnosis was made by histological examination of a skin biopsy, which showed numerous acid‐fast bacilli. A culture grown from a skin biopsy isolated a resistant Mycobacterium tuberculosis strain. The papules disappeared within a few days after starting treatment with pyrazinamide, isoniazid and moxifloxacin. 相似文献
92.
U. Logonder Z. Jenko-Pranikar T. Scott-Davey J. Punger
ar I. Kriaj J.B. Harris 《Experimental neurology》2009,219(2):591-594
A mutant form of ammodytoxin A, a neurotoxic phospholipase A2 from the venom of the long nosed viper Vipera ammodytes ammodytes, was prepared by site-directed mutagenesis, conjugated to a nanogold particle and inoculated into the antero-lateral aspect of one hind limb of female mice. Eight hours later the mice were killed, the soleus muscles of both ipsi- and contra-lateral hind limbs were removed, exposed to a silver enhancing medium and then prepared for transmission electron microscopy. Silver-enhanced particles were subsequently found concentrated in the peri-synaptic area, particularly within the synaptic gutter and the deep synaptic folds, and in many cases had been taken up into the cytoplasm of the terminal boutons of the motor axon. The results suggest that the presynaptic neurotoxicity of snake venom phospholipases A2 involves several components of the neuromuscular apparatus, including intracellular organelles of the motor nerve terminal. 相似文献
93.
Marta Méndez-López Magdalena Méndez Fernando Sánchez-Patán Isabel Casado Maria-Angeles Aller Laudino López Maria-Teresa Corcuera Maria-Jose Alonso Maria-Paz Nava Jaime Arias Jorge-Luis Arias 《Journal of gastrointestinal surgery》2007,11(2):187-194
To obtain a new model of chronic portal hypertension in the rat, two classical methods to produce portal hypertension, partial portal vein ligation and the oral administration of thioacetamide (TAA), have been combined. Male Wistar rats were divided into four groups: 1 (control; n?=?10), 2 [triple partial portal vein ligation (TPVL); n?=?9], 3 (TAA; n?=?11), and 4 (TPVL plus TAA; n?=?9). After 3 months, portal pressure, types of portosystemic collateral circulation, laboratory hepatic function tests (aspartate aminotransferase, alanine aminotransferase, bilirubin, alkaline phosphatase, and gamma-glutamyl transpeptidase) and liver histology were studied. The animals belonging to group 2 (TPVL) developed extrahepatic portosystemic collateral circulation, associated with mesenteric venous vasculopathy without hepatic destructurization or portal hypertension. Animals from group 3 (TAA) developed cirrhosis and portal hypertension but not extrahepatic portosystemic collateral circulation, or mesenteric venous vasculopathy. Finally, the animals from group 4 (TPVL?+?TAA) developed cirrhosis, portal hypertension, portosystemic collateral circulation, and mesenteric venous vasculopathy. The association of TPVL and TAA can be used to obtain a model of chronic portal hypertension in the rat that includes all the alterations that patients with hepatic cirrhosis usually have. This could, therefore, prove to be a useful tool to study the pathophysiological mechanisms involved in these alterations. 相似文献
94.
95.
96.
97.
98.
99.
100.
Raúl González-García Francisco J Rodríguez-Campo Verónica Escorial-Hernández Mario F Mu?oz-Guerra Jesús Sastre-Pérez Luis Naval-Gías José L Gil-Díez Usandizaga 《Journal of oral and maxillofacial surgery》2006,64(11):1587-1591
PURPOSE: Temporomandibular joint (TMJ) arthroscopy has been considered a safe surgical procedure in the treatment of TMJ derangement. However, it is not exempt from complications. This study evaluates the complications of arthroscopy in patients with internal derangement of TMJ. PATIENTS AND METHODS: Five hundred consecutive patients (670 joints) with TMJ derangement who underwent arthroscopy between 1995 and 2004 were retrospectively analyzed. All the patients were classified as II to V in the Wilkes classification. Lysis and lavage, electrocautery of the posterior ligament, injection of corticoids, injection of ethanolamine, myotomy of lateral pterygoid muscle attachments, myotomy and electrocautery, motor debridement, injection of sodium hyaluronate, and meniscal suture were performed in different patients. RESULTS: Complications were recognized during or immediately after the surgery. They were observed in 5 of 341 (1.26%) arthroscopies of the right TMJ and 4 of 329 (1.21%) arthroscopies of the left TMJ. A 1.34% complication rate was found in the whole series. No blood clots within the external auditory canal were observed. Bleeding within the superior TMJ space was observed in 57 cases (8.5%), 36 of them in the right TMJ and 21 in the left TMJ, but they were not considered as true complications. Lacerations of the external auditory canal were found in 2 cases (0.3%), with no cases of perforation of the tympanic membrane. Lesion of the auriculotemporal nerve was observed in a case. Paresia of the facial nerve was found in 4 cases (0.6%). Alteration of visual accuracy of the ipsilateral eye was also observed in a patient immediately after the surgery. CONCLUSION: Special care must be taken to reduce complications within the upper joint space by means of an adequate instrumentation and by paying attention to essential points of the arthroscopic technique. 相似文献