Using rare earth element tracers and neutron activation analysis to study rill erosion process.

Spatially averaged soil erosion data provide little information on the process of rill erosion. The dynamically varied data on the temporal and spatial distributions in the rill erosion process are needed to better understand the erosion process and reveal its innate characteristics. The objectives of this study were to examine the feasibility and effectiveness of rare earth element (REE) tracers and the neutron activation analysis (NAA) method on the study of the rill erosion process and to reveal quantitatively the relationships and characteristics of temporal and spatial distributions of sediment yield in rill erosion. Four REEs were used to study the changeable process of rill erosion at 4 slope positions. Four water inflow rates were applied to a 0.3 x 5 m soil bed at 3 slopes of 10.5%, 15.8% and 21.2% in scouring experiments. All of the runoff was collected in the experiment. Each sample was air-dried and well mixed. Then 20 g of each sample was sieved through 100-mesh and about a 50 mg sample was weighed for analysis of the four elemental compositions by NAA. Results indicate that the REE tracers and NAA method can be used to not only quantitatively determine soil erosion amounts on different slope segments, but also to reveal the changeable process of rill erosion amount. All of the relative errors of the experimental results were less than 25%, which is considered satisfactory on the study of rill erosion process.     

中西医结合治疗急性缺血性中风的临床研究

随着我国社会的日益老龄化，人们生活水平的不断提高和生活方式的改变，中风病的发病率逐年上升，严重危害人类生命与健康，给家庭和社会带来沉重的负担。笔者近二年来，对急性缺血性中风患者100例分别采用中西医结合治疗及单纯西药治疗，并进行了临床观察研究，现将结果报告如下。     

Proteasome Inhibitors Sensitize Hepatocellular Carcinoma Cells to TRAIL

A poptosis, an evolutionarily conserved form of cell suicide, oc- curs in two physiological stages: commitment and execution.[1] It has been found that several Bcl-2 family proteins are located in the outer mitochondrial membrane, where they control relea…     

王焕禄老中医治疗哮喘发作期的用药经验

王焕禄老中医在长期的临床实践中，总结出治疗哮喘病的一些用药体会，兹介绍如下，以飨读者。     

多巴胺转运体440bp等位基因与儿童孤独症的关系

目的探讨儿童孤独症(CA)与多巴胺转运体(DAT1)440bp等位基因的关系。 方法陕西省纺织医院等于2004年3~8月，采用PCR技术对来自西安市两所康复中心的汉族CA儿童与DAT1基因多态性进行遗传关联分析。 结果(1)DAT1基因多态性中共观察到5种等位基因(320bp，360bp，440bp，480bp，520bp)，6种基因型(480/480，480/320，520/480，480/360，480/440,440/440)。(2)使用相对危险度RR对CA与DAT1基因多态性的等位基因和基因型进行关联分析，显示480/440基因型和等位基因440与CA呈正关联，相对危险度分别为265和230，480/480基因型和等位基因480与CA呈负关联，相对危险度分别为064和077。但统计结果没有发现具有统计意义的差异。 结论中国汉族CA儿童与DAT1440bp等位基因无遗传关联。也许等位基因440bp与基因型480bp/440bp这两个因素是发病的风险因素,还有待今后的进一步研究。     

深圳市青少年心理叛逆的相关因素探讨

目的 了解深圳市青少年心理叛逆的表现并探讨其影响因素，为预防心理叛逆提供相关理论依据。方法 2005年3月至5月，采用分层整群随机抽样方法，选取19所深圳市大、中学校学生4000名，进行青少年心理叛逆的相关表现及行为调查。结果作为心理叛逆的表现之一，20．8％的深圳市青少年近一年有过离家出走的想法，5．8％的人曾经尝试过离家出走，其中男生尝试离家出走率为7．4％，女生为4．3％。初中／高中学生离家出走想法的发生率高于大学生（x^2=51．1，P=0．000），但不同学校类型问尝试离家出走的差别无统计学意义（x^2=1．9，P=0．392）。在过去12个月中孤独感、在过去12个月中失眠的次数、在过去12个月中是否连续两周感到伤心或绝望、网络成瘾、在过去1个月中平均每天的吸烟量、在过去1个月中平均每天的饮酒量是尝试离家出走的危险因素，而女生、学习成绩好是其保护因素。结论 深圳市大、中学生心理叛逆较普遍，他们中离家出走想法和尝试离家出走的发生率较高，常与社会心理因素有关，消除危险因素，加强健康教育可最大限度预防青少年的心理叛逆。     

狂犬疫苗免疫后早期血清学抗体结果分析

目的观察接种狂犬病疫苗人群不同时期抗体产生情况，探讨最佳检测时间。方法用ELISA法检测人用狂犬病纯化疫苗接种者血清狂犬病毒抗体。结果对完成全程免疫后第7d、第14d和第30d的血清进行检测，第7d和第14d检出的抗体阳性率无显著性差异。结论现行国产狂犬疫苗的保护性不断提高，早期检测抗体对及时发现免疫失败者、降低发病率有着重要的意义。     

Effects of cerulenin on the endogenous fatty acid synthetic activity in squamous cell carcinoma of the oral cavity.

PURPOSES: Inhibition of cerulenin on the endogenous fatty acid synthetic activities of oral squamous cell carcinoma (OSCC) and normal oral mucosa was assayed. METHODS: Squamous cell carcinoma and normal oral mucosa were collected fresh from surgical specimens. The collected tissues were minced in RPMI 1640 and divided into 3 groups: cerulenin treated, dimethylsulfoxide treated, and control. The tissues were incubated in [1(2)-(14)C]acetic acid, sodium salt for the last 2.5 hours of the treatment at 37 degrees C in 5% CO(2). After labeling, total lipids were extracted and counted for (14)C by scintillation counting. RESULTS: Endogenous fatty acid synthetic activities of oral squamous cell caranoma in the cerulenin-treated group decreased by 19% at 1 hour, 64% at 2 hours, and 87% at 4 hours; remained nearly unchanged in the dimethylsulfoxide-treated group; and increased slightly in the control group. The oral mucosa tissues were only mildly affected by cerulenin in fatty acid synthesis. CONCLUSIONS: Cerulenin significantly inhibits fatty acid synthetic activity in squamous cell carcinoma and only mildly affected the oral mucosa, indicating that the fatty acid synthetic pathway may be exploited as a target for developing anticancer drugs.