全文获取类型
收费全文 | 415978篇 |
免费 | 38485篇 |
国内免费 | 29345篇 |
专业分类
耳鼻咽喉 | 3265篇 |
儿科学 | 5255篇 |
妇产科学 | 4599篇 |
基础医学 | 45652篇 |
口腔科学 | 6744篇 |
临床医学 | 58574篇 |
内科学 | 56394篇 |
皮肤病学 | 4440篇 |
神经病学 | 20243篇 |
特种医学 | 15404篇 |
外国民族医学 | 260篇 |
外科学 | 37068篇 |
综合类 | 77905篇 |
现状与发展 | 89篇 |
一般理论 | 36篇 |
预防医学 | 30500篇 |
眼科学 | 11666篇 |
药学 | 45410篇 |
477篇 | |
中国医学 | 27127篇 |
肿瘤学 | 32700篇 |
出版年
2024年 | 1388篇 |
2023年 | 6017篇 |
2022年 | 15860篇 |
2021年 | 20038篇 |
2020年 | 15807篇 |
2019年 | 12909篇 |
2018年 | 13492篇 |
2017年 | 12885篇 |
2016年 | 11919篇 |
2015年 | 18616篇 |
2014年 | 23059篇 |
2013年 | 20888篇 |
2012年 | 31130篇 |
2011年 | 34928篇 |
2010年 | 23572篇 |
2009年 | 19102篇 |
2008年 | 23478篇 |
2007年 | 23342篇 |
2006年 | 22418篇 |
2005年 | 21363篇 |
2004年 | 14393篇 |
2003年 | 14110篇 |
2002年 | 11702篇 |
2001年 | 10036篇 |
2000年 | 9550篇 |
1999年 | 9576篇 |
1998年 | 6154篇 |
1997年 | 5863篇 |
1996年 | 4523篇 |
1995年 | 4291篇 |
1994年 | 3630篇 |
1993年 | 2279篇 |
1992年 | 2769篇 |
1991年 | 2424篇 |
1990年 | 2028篇 |
1989年 | 1780篇 |
1988年 | 1448篇 |
1987年 | 1307篇 |
1986年 | 1073篇 |
1985年 | 757篇 |
1984年 | 404篇 |
1983年 | 298篇 |
1982年 | 162篇 |
1981年 | 191篇 |
1980年 | 134篇 |
1979年 | 165篇 |
1978年 | 75篇 |
1977年 | 54篇 |
1974年 | 42篇 |
1972年 | 37篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
21.
22.
23.
Parallel enzyme‐linked immunosorbent assay screening for human immunodeficiency virus among blood donors in five Chinese blood centres: a retrospective analysis 下载免费PDF全文
24.
Kui Li Jiawen Wang Shengxiong Liu Sen Su Chenjian Feng Xiaoxiang Fan Zhiyong Yin 《中华创伤杂志(英文版)》2015,18(2):65-73
Objective: To study the biomechanical mechanism of head injuries beaten with sticks, which is common in the battery or assaultive cases.
Methods: In this study, the Hybrid-III anthropomorphic test device and finite element model (FEM) of the total human model for safety (THUMS) head were used to determine the biomechanical response of head while being beaten with different sticks. Total eight Hybrid-III tests and four finite element simulations were conducted. The contact force, resultant acceleration of head center of gravity, intracranial pressure and von Mises stress were calculated to determine the different biomechanical behavior of head with beaten by different sticks.
Results: In Hybrid-III tests, the stick in each group demonstrated the similar kinematic behavior under the same loading condition. The peak values of the resultant acceleration for thick iron stick group, thin iron stick group, thick wooden stick group and thin wooden stick group were 203.4 g, 221.1 g, 170.5 g and 122.2 g respectively. In finite element simulations, positive intracranial pressure was initially observed in the frontal comparing with negative intracranial pressure in the contra-coup site. Subsequently the intracranial pressure in the coup site was decreasing toward negative value while the contra-coup intracranial pressure increasing toward positive values.
Conclusions: The results illustrated that the stiffer and larger the stick was, the higher the von Mises stress, contact force and intracranial pressure were. We believed that the results in the Hybrid-III tests and THUMS head simulations for brain injury beaten with sticks could be reliable and useful for better understanding the injury mechanism. 相似文献
25.
Multidisciplinary predialysis education and team care (MDC) may slow the decline in renal function in patients with chronic kidney disease (CKD). However, associations between unexpected return during MDC and progression of renal dysfunction have not been characterized in patients with CKD. Our study aimed to determine the association between exacerbation of renal dysfunction and the frequency of unexpected return during follow-up.A total of 437 patients with CKD receiving multidisciplinary care between January 2009 and June 2013 at the Shin-Kong Wu Ho-Su Memorial Hospital were included in this retrospective observational cohort study, and multiple imputations were performed for missing data. The predictor was the frequency of unexpected return for follow-up during the first year after entering MDC. Main outcome was monthly declines in estimated glomerular filtration rates (eGFR). Moreover, the demographic data, comorbidities, history of medication, and routine laboratory data for patients with CKD were collected.Among all patients, 59.7% were male, the mean age at initiation of MDC was 69.4 ± 13.2 years, and the duration of follow-up was 21.4 ± 3.3 months. The subjects were divided into 2 groups according to frequencies of follow-up (≤4 and > 4 visits) during the 1st year of MDC. The patients with CKD were regularly followed up every 3 months as a part of MDC in our hospital, and patients who returned for more than 4 follow-up visits were included in the unexpected return group. In crude regression analyses, unexpected return was significantly associated with higher monthly declines of eGFR (β = 0.092, 95% confidence interval, 0.014–0.170). This association remained after adjustments for multiple variables, and subgroup analyses of unexpected return showed that male gender, older age, CKD stage 1 to 3, hypertension, history of coronary artery disease, and use of renin–angiotensin system blockade were significantly associated with declines in renal function.In conclusion, unexpected return for follow-up during the 1st year of MDC was significantly associated with the deterioration of renal function. 相似文献
26.
目的:分析糖尿病视网膜病变合并黄斑水肿联合采用激光与复方血栓通胶囊治疗的临床疗效。方法:选取我院2017年1月—2019年1月收治的200例糖尿病视网膜病变合并黄斑水肿患者为研究对象,随机分为两组。对照组单独行激光治疗,观察组于对照组基础上联合复方血栓通胶囊治疗,对比两组临床疗效、治疗前后IL-6(白介素-6)、VEGF(血管内皮生长因子)、NOS(血清一氧化氮合成酶)水平变化情况。结果:对照组总有效率(68.00%,68/100)较观察组总有效率(98.00%,98/100)更高(P<0.05);与对照组对比,观察组治疗后NOS水平更高,IL-6、VEGF水平更低(P<0.05)。结论:糖尿病视网膜病变合并黄斑水肿联合采用激光与复方血栓通胶囊治疗的临床疗效显著,值得推广。 相似文献
27.
28.
Ling Zhang Xue-Jun Shang Hong-Fei Li Yu-Qin Shi Wei Li Maria E Teves Zhi-Qiong Wang Gao-Feng Jiang Shi-Zhen Song Zhi-Bing Zhang 《Asian journal of andrology》2015,17(1):86-93
Mammalian spermatogenesis is a well-organized process of cell development and differentiation. Meiosis expressed gene 1 (MEIG1) plays an essential role in the regulation of spermiogenesis. To explore potential mechanisms of MEIG1''s action, a yeast two-hybrid screen was conducted, and several potential binding partners were identified; one of them was membrane occupation and recognition nexus repeat containing 3 (MORN3). MORN3 mRNA is only abundant in mouse testis. In the testis, Morn3 mRNA is highly expressed in the spermiogenesis stage. Specific anti-MORN3 polyclonal antibody was generated against N-terminus of the full-length MORN3 protein, and MORN3 expression and localization was examined in vitro and in vivo. In transfected Chinese hamster ovary cells, the antibody specifically crossed-reacted the full-length MORN3 protein, and immunofluorescence staining revealed that MORN3 was localized throughout the cytoplasm. Among multiple mouse tissues, about 25 kDa protein, was identified only in the testis. The protein was highly expressed after day 20 of birth. Immunofluorescence staining on mixed testicular cells isolated from adult wild-type mice demonstrated that MORN3 was expressed in the acrosome in germ cells throughout spermiogenesis. The protein was also present in the manchette of elongating spermatids. The total MORN3 expression and acrosome localization were not changed in the Meig 1-deficient mice. However, its expression in manchette was dramatically reduced in the mutant mice. Our studies suggest that MORN3 is another regulator for spermatogenesis, probably together with MEIG1. 相似文献
29.
30.