缺锌和补锌对运动大鼠锌营养状况的影响

通过建立大鼠缺锌模型，观察缺锌及补锌对游泳大鼠血清、肝脏锌含量和五种含锌金属酶活性的影响。结果表明：（１）血浆锌浓度和碱性磷酸酶（ＡＫＰ）活性是评价机体锌缺乏的灵敏指标；（２）血浆ＡＫＰ活性同时也是评价运动大鼠锌缺乏的较好指标，而血管紧张素Ｉ转换酶、酸性α－Ｄ－甘露糖苷酶５－核苷酸酶等不太理想；（３）运动时，缺锌大鼠血浆锌金属酶活性多数变化剧烈，表明机体内环境遭受较大破坏。而补锌后上述指标均接近正常水平，说明适量补锌有助于改善机体缺锌状况，维持机体内环境的稳定     

肘部尺神经半脱位的解剖学和流行病学研究

目的：研究肘部尺神经半脱位的发生原因及其临床意义。方法：对１００侧成人尸体肘部的尺神经位置进行解剖观察；在人群中随机调查了８５４位正常人肘部尺神经的位置。结果：肘管深度为７．１±０．１４ｍｍ（χ±ｓχ）。解剖观察发现，６侧肢体的尺神经在屈肘时发生半脱位，肘管深度平均为４．８ｍｍ。８５４位正常人肘部尺神经半脱位发生率为８．９％（７６／８５４）。结论：绝大多数的肘部尺神经半脱位是先天性的。肘部尺神经半脱位不一定是肘部尺神经卡压的发病原因。     

A study on various symptoms of chronic hepatitis treated with radix astragali and its regulative effect to levels of serum hormone

Sixty-seven cases of chronic hepatitis were treated with Radix Astragali. After treatment (2-month course), the clinical improvement rate in 38 cases of the Stagnation of the Liver-Qi and Deficiency of the Spleen type was 92.1%, and in 26 cases of the Deficiency of Liver Yin and Kidney Yin type was 88.5%, more effective than in the control group (P<0.05). The regulative effect to the levels of serum hormone was observed in the patients of the Stagnation of the Liver-Qi and Deficiency of the Spleen type treated with this medicine. The results showed that the levels of serum triiodothyronine, estradiol (female) and testosterone (male) were increased after treatment (1.40±1.38 ng/dl, 129.30±1.23 pg/ml and 496.24±1.47 ng/dl). Pre-treatment levels were 1.22±1.49 ng/dl, 104.60±1.45 pg/ml and 398. 17±1.55 ng/dl respectively (P<0.05); however, the level of serum prolactin (2.75±4.46 ng/ml) was lower after treatment than before treatment (3.20±3.82 ng/ml,P<0.05). No obvious changes were observed in the levels of serum follicle stimulating hormone, luteinizing hormone, thyroid stimulating hormone, thyroxine, triiodothyronine uptake ratio and cortisol after treatment.     

Pharmacokinetics of intravenously administered sodium dichloroacetate in rabbits

ＰｈａｒｍａｃｏｋｉｎｅｔｉｃｓｏｆｉｎｔｒａｖｅｎｏｕｓｌｙａｄｍｉｎｉｓｔｅｒｅｄｓｏｄｉｕｍｄｉｃｈｌｏｒｏａｃｅｔａｔｅｉｎｒａｂｂｉｔｓＧｕＢｉｎ（顾斌）；ＳｏｎｇＬｉｎｇ（宋岭）；ＪｉａｎｇＹｏｎｇｐｅｉ（蒋永培）；ＷｅｎＡｉｄｏｎｇ（文...     

Radioimmunoassay method for the detection of IgE antibodies specific to alcuronium

A radio-immunoassay (RIA) was used to screen for specific IgE to myorelaxants. Alcuronium was coupled to epoxy-activated Sepharose. Sixteen patients with anaphylaxis to alcuronium (n = 2), gallamine (n = 2) or suxamethonium (n = 12) were studied. The diagnosis was established by intradermal tests (ID), passive cutaneous anaphylaxis tests and human basophil degranulation tests. The amount of non specific label retained by Sepharose-ethanolamine (with sera of patients) and Sepharose-alcuronium (with sera of 11 control subjects) was estimated. The RIA was positive 10/16 (8/14 patients having reacted to a muscle relaxant other than alcuronium). The RIA seemed to be useful in the diagnosis of anaphylaxis to muscle relaxants. Drug-reactive antibodies were specific of the quaternary ammonium radical, which was the common allergenic determinant of all molecules of muscle relaxants. This test accounted for in vitro cross-reactivity, but had no predictive value for the clinical risk of crossed-anaphylaxis. This risk was best assessed by ID; it was positive in three cases. Although it was not possible to compare ID and RIA, the interpretation of which was different, both tests should be recommended for the detection of sensitivity to muscle relaxants.     

Cancer of esophagus and esophagogastric junction: analysis of results of 1,025 resections after 5 to 20 years

Resection was carried out in 1,025 of 1,654 patients with cancer of the esophagus or esophagogastric junction at the Peking Medical College Hospitals in China from 1953 through 1973. All cancers of the esophagus were squamous cell carcinomas except for five adenocarcinomas. A lesion localized within the esophageal wall was found in 55% and lymph node metastasis in 41.3% of the patients undergoing resection. All cancers of the esophagogastric junction were adenocarcinomas. The tumor had invaded beyond the boundaries of the stomach in 76.7% of these patients, and positive nodes were found in 61% of the patients. The rate of resectability was 81.2% for esophageal cancer and 74% for cancer of the esophagogastric junction. Surgical mortality after resection was 4.9% (50/1,025). The 5-year survival after resection was 20.9% (214/1,025). Better results were found following complete resection: 24% (210/875) for all patients, 28.2% (162/575) for patients with cancer of the esophagus, and 16% (48/300) for patients with cancer of the esophagogastric junction. Late survival at 10, 15, and 20 years after resection of esophageal cancer was 20%, 12%, and 7.4%, respectively. The favorable prognostic factors after resection of esophageal cancer were tumor of the lower third of the esophagus, the absence of lymph node involvement, and the presence of a localized lesion. The 5-year survival for patients with cancer of the lower third of the esophagus was 32.7%. It was 64.2% for patients with a localized lesion with negative nodes in this subgroup.     

介入手术治疗异位妊娠12例临床分析

目的：探索一种治疗输卵管妊娠的微创介入手术，解决因其腹腔出血不能接受保守治疗或保守治疗失败的难题。保持输卵管完整及通畅，满足有生育需求的患。方法：对12例输卵管妊娠妇女行对侧股动脉穿刺，将导管超选择插至子宫动脉以甲氨喋呤(MTX)进行灌注及明胶海绵栓塞术。结果：本组病例中，术后10dB超复查孕囊脱落、吸收消失，栓塞后盆腔活动性出血停止。结论：介入治疗宫外孕输卵管妊娠，能有效杀灭胚胎组织，栓塞破裂血管止血效果明显，且能保持输卵管通畅。     

大学生蠕形螨感染的调查分析

目的调查广州医学院2001级大学生人体蠕形螨的感染情况,探讨蠕形螨感染与皮肤疾病、宿舍分布的关系。方法采用透明胶纸粘贴法对468名在校大学生蠕形螨感染进行调查,同时观察其面部皮肤状况,询问其所住宿舍状况并记录于调查表内。结果广州医学院2001级大学生468人,检出人体蠕形螨者85人,感染率18.16%。男学生感染率为18.37%(52/283人),女学生为17.84%(33/185人),两者无显著性差异(P>0.05)。从学生来源地看,城镇学生感染率为15.94%(51/320人),农村学生为22.97%(34/148人),两者无显著性差异(P>0.05)。感染者的感染度以每条透明胶纸1～3条虫为多,占87.06%(74/85人)。检获的螨大多为毛囊蠕形螨,占70.59%(60/85人),单一感染皮脂蠕形螨仅15.29%(13/85人),两者混合感染为14.12%(12/85人)。面部有痤疮、毛囊炎或毛囊扩张者蠕形螨感染率均高于面部皮肤正常、有痒感者(P<0.05);有痒感者蠕形螨感染率与面部皮肤正常者无显著性差异(P>0.05)。感染蠕形螨者具有显著的宿舍聚集性(P<0.01)。结论广州医学院2001级大学生人体蠕形螨感染较为普遍。感染大多为毛囊蠕形螨,少数为皮脂蠕形螨及两者混合感染,两种蠕形螨的感染度都属轻度。蠕形螨感染可能是痤疮、毛囊炎或毛囊扩张等皮肤疾病的致病因素之一。蠕形螨感染可以通过同     

刍议大学生自杀原因及预防措施

探讨大学生自杀原因及其心理干预策略。