全文获取类型
收费全文 | 2976篇 |
免费 | 168篇 |
国内免费 | 8篇 |
专业分类
耳鼻咽喉 | 18篇 |
儿科学 | 100篇 |
妇产科学 | 68篇 |
基础医学 | 270篇 |
口腔科学 | 57篇 |
临床医学 | 228篇 |
内科学 | 631篇 |
皮肤病学 | 103篇 |
神经病学 | 93篇 |
特种医学 | 84篇 |
外科学 | 425篇 |
综合类 | 349篇 |
一般理论 | 3篇 |
预防医学 | 150篇 |
眼科学 | 59篇 |
药学 | 204篇 |
1篇 | |
中国医学 | 12篇 |
肿瘤学 | 297篇 |
出版年
2023年 | 28篇 |
2022年 | 61篇 |
2021年 | 127篇 |
2020年 | 64篇 |
2019年 | 75篇 |
2018年 | 92篇 |
2017年 | 59篇 |
2016年 | 86篇 |
2015年 | 113篇 |
2014年 | 107篇 |
2013年 | 137篇 |
2012年 | 220篇 |
2011年 | 218篇 |
2010年 | 176篇 |
2009年 | 117篇 |
2008年 | 165篇 |
2007年 | 192篇 |
2006年 | 145篇 |
2005年 | 131篇 |
2004年 | 129篇 |
2003年 | 93篇 |
2002年 | 92篇 |
2001年 | 56篇 |
2000年 | 31篇 |
1999年 | 44篇 |
1998年 | 39篇 |
1997年 | 39篇 |
1996年 | 41篇 |
1995年 | 33篇 |
1994年 | 28篇 |
1993年 | 14篇 |
1992年 | 28篇 |
1991年 | 13篇 |
1990年 | 12篇 |
1989年 | 12篇 |
1988年 | 10篇 |
1987年 | 14篇 |
1986年 | 15篇 |
1985年 | 12篇 |
1984年 | 12篇 |
1983年 | 6篇 |
1982年 | 7篇 |
1981年 | 7篇 |
1979年 | 4篇 |
1978年 | 5篇 |
1977年 | 4篇 |
1976年 | 6篇 |
1970年 | 6篇 |
1969年 | 5篇 |
1968年 | 4篇 |
排序方式: 共有3152条查询结果,搜索用时 15 毫秒
11.
12.
13.
Splenic T cells from myelin basic protein (MBP)-immunised Lewis rats were activated to transfer experimental autoimmune encephalomyelitis (EAE) by co-culture with MBP-pulsed lymphoid dendritic cells (DC). MBP-pulsed DC could be kept for at least 24 h at 37 degrees C in antigen-free medium without affecting their ability subsequently to activate encephalitogenic T cells. However, MBP-pulsed DC were rendered much less stimulatory after a 6 h, but not 2 h, secondary incubation with ovalbumin. Thus, although encephalitogenic complexes between MBP and DC appear very stable in the absence of competing antigens, in their presence, antigen exchange can take place over a period of a few hours; this has positive implications for therapy of EAE by antigen competition. 相似文献
14.
A study conducted in 1990 revealed that 2% (range 0.6-4.8) of negative blood smears were mislabelled as positive, and 6.7% of positive blood smears were mislabelled as negative. A result of such mislabelling would be inadequate treatment of a large number of patients. Hence the need to look into the training aspect and system of supervision of laboratory technicians. The present system of cross-checking of blood smears at different levels also needs to be reviewed. A study which could address itself to these needs is indicated. 相似文献
15.
16.
17.
18.
A. Gautam S.A. Fischer A.F. Yango R.Y. Gohh P.E. Morrissey A.P. Monaco 《International immunopharmacology》2006,6(13-14):2023
Cell mediated immunity (CMI) was assessed by the ImmuKnow assay in 12 patients after kidney transplantation, who presented with viral infection. Treatment included lowering of immunosuppression in all cases and antiviral treatment if indicated. The assay was repeated during the follow up. The ImmuKnow assay at time of presentation of viral infections was 56.8 ± 58.2 (range 3–178; median 22) ATP ng/ml. With the clearance of viral infection and lowering of immunosuppression, the assay showed an increase in the level of CMI at 194.5 ± 118.9 (range 53–409; median 150) ATP ng/ml. There was viral clearance or stabilization in all cases and there was no incidence of allograft rejection. The ImmuKnow assay of CMI can be used to titrate initial immunosuppression reduction and its subsequent increase, in patients with viral infection after transplantation. 相似文献
19.
Preemptive Plasmapheresis and Recurrence of FSGS in High-Risk Renal Transplant Recipients 总被引:2,自引:0,他引:2
R. Y. Gohh A. F. Yango P. E. Morrissey A. P. Monaco A. Gautam M. Sharma E. T. McCarthy V. J. Savin 《American journal of transplantation》2005,5(12):2907-2912
Recurrent focal segmental glomerulosclerosis (FSGS) following transplantation is ascribed to the presence of a circulating FSGS permeability factor (FSPF). Plasmapheresis (PP) can induce remission of proteinuria in recurrent FSGS. This study addressed the efficacy of pre-transplant PP in decreasing the incidence of recurrence in high-risk patients. Ten patients at high-risk for FSGS recurrence because of rapid progression to renal failure (n = 4) or prior transplant recurrence of FSGS (n = 6) underwent a course of 8 PP treatments in the peri-operative period. Recurrences were identified by proteinuria >3 g/day and confirmed by biopsy. Seven patients, including all 4 with first grafts and 3 of 6 with prior recurrence, were free of recurrence at follow-up (238-1258 days). Final serum creatinine in 8 patients with functioning kidneys averaged 1.53 mg/dL. FSGS recurred within 3 months in 3 patients, each of whom had lost prior transplants to recurrent FSGS. Two of these progressed to end-stage renal disease (ESRD) and the third has significant renal dysfunction. Based on inclusion criteria, recurrence rates of 60% were expected if no treatment was given. Therefore, PP may decrease the incidence of recurrent FSGS in high-risk patients. Definitive conclusions regarding optimal management can only be drawn from larger, randomized, controlled studies. 相似文献
20.