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991.
BackgroundTwo recent literature-based meta-analyses revealed that restrictive filling pattern (RFP) was associated with a 4-fold increase in the risk of death in patients with heart failure (HF) and postacute myocardial infarction (AMI). This similar but unique analysis evaluated the link between RFP and morbidity.Methods and ResultsProspective echocardiographic studies of patients post-AMI and with HF that reported HF morbidity were identified. Events (post-AMI: development of HF; HF: HF readmission) were compared between patients with and without RFP in both patient groups. Review Manager version 4.2.7 software was used for the analysis. Twelve post-AMI studies (1286 patients, 271 events) and 5 HF studies (647 patients, 176 events) were identified. RFP was associated with HF readmission in the HF patients (OR 2.96 [2.02–4.33] and development of HF post-AMI (OR 10.10 [7.02–14.51]). The event rate in the RFP group was the same regardless of disease category (49% post-AMI, 42% HF); however, RFP was less prevalent in the post-AMI group (22% versus 39%).ConclusionsThis literature-based meta-analysis confirms that RFP is a powerful predictor of HF hospitalization in patients with HF and especially the development of HF post-AMI. This is an important prognostic sign and should be incorporated into routine clinical practice. 相似文献
992.
Dr Michael T. Matteson PhD Dr John M. Ivancevich PhD Dr George O. Gamble DBA 《Behavioral medicine (Washington, D.C.)》2013,39(1):23-31
Abstract Portions of the cognitive social learning model proposed by Price1.2 as an explanation for the development and maintenance of Type A behavior were examined empirically. Specifically, the hypothesis that Type A behavior is fostered by various beliefs and fears and that these same beliefs and fears arise, in part, as the result of certain parental characteristics was investigated. A questionnaire assessing Type A behavior and the beliefs, fears, and parental characteristics proposed by Price was constructed and administered to a sample of males and females. The results indicated moderate associations between the variables examined for both males and females, with no significant gender differences in the pattern of relationships. The findings are congruent with relationships proposed by Price's model. Implications of the model are discussed in terms of additional research needed. 相似文献
993.
994.
Erika J. MacIntyre Sumit R. Majumdar John-Michael Gamble Jasjeet K. Minhas-Sandhu Thomas J. Marrie Dean T. Eurich 《The American journal of medicine》2012,125(10):1036.e17-1036.e23
ObjectiveOur goal was to determine the association between random admission hyperglycemia and new diagnosis of diabetes after discharge in patients hospitalized with pneumonia.MethodsClinical data, including the Pneumonia Severity Index, were prospectively collected on all 2124 patients without diabetes admitted with pneumonia to 6 hospitals in Edmonton, Alberta, Canada. Admission glucose was classified as: normal (4.0-6.0 mmol/L, reference group) versus mild (6.1-7.7 mmol/L), moderate (7.8-11.0 mmol/L), and severe (11.1-20.0 mmol/L) stress hyperglycemia. New diagnosis of diabetes over 5 years was ascertained using well-validated criteria within linked administrative databases. Multivariable Cox models were used, and sensitivity, specificity, and likelihood ratios were calculated.ResultsMean age was 68 years; 1091 (51%) were male, and 1418 (67%) had stress hyperglycemia. Over 5 years, 194 (14%) with stress hyperglycemia were diagnosed with diabetes. Compared with the 45 of 706 (6%) incidences of diabetes in normal glycemia patients (4.0-6.0 mmol/L), a strong graded increase in risk of new diabetes existed with increasing hyperglycemia: mild (59 of 841 [7%]; adjusted hazard ratio [aHR] 1.09; 95% confidence interval [CI], 0.74-1.61) versus moderate (86 of 473 [18%]; aHR 2.99; 95% CI, 2.07-4.31) versus severe (49 of 104 [47%]; aHR 11.43; 95% CI, 7.50-17.42). Among moderate-to-severe hyperglycemia (≥7.8 mmol/L) patients, the sensitivity, specificity, and positive and negative likelihood ratios for new diabetes were 57%, 77%, 2.1, and 0.6, respectively, with a number-needed-to-evaluate of 5 to detect one new case of diabetes.ConclusionModerate-to-severe random hyperglycemia in pneumonia patients admitted to the hospital is strongly associated with new diagnosis of diabetes. Opportunistic evaluation for diabetes may be warranted in this group. 相似文献
995.
996.
Wei Zhang Tomoko Fujiwara Hűmeyra Taşkent Ying Zheng Kennard Brunson Lara Gamble Kenneth J. Wynne 《Macromolecular chemistry and physics.》2012,213(14):1415-1434
A conventional MDI‐BD‐PTMO polyurethane is modified using 2 wt% polyurethanes (U) having copolyoxetane soft blocks with hydrophobic 3F, CF3CH2OCH2— and hydrophilic MEn, CH3O(CH2CH2O)nCH2—, n = 3, 7) side chains. In contrast to neat 3F‐co‐MEn‐U, 2 wt% 3F‐co‐MEn‐U compositions have physically stable morphologies and wetting behavior. Surface composition (XPS) and amphiphilic or contraphilic wetting are controlled by the 3F‐co‐MEn polyoxetane soft block architecture and MEn side chain length. Importantly, θrec can be tuned for 2 wt% 3F‐co‐MEn‐U compositions independent of swelling, which is controlled by the bulk polyurethane. AFM imaging leads to a new morphological model whereby fluorous/PEG‐hard block nanoaggregates combine to form near surface features culminating in micron‐scale texturing. 相似文献
997.
What factors influence successful recruitment of siblings of individuals with first episode psychosis to e‐health interventions? A qualitative study
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998.
Jones C Bryant-Waugh R Turner HM Gamble C Melhuish L Jenkins PE 《Eating behaviors》2012,13(2):146-149
Guided self-help (GSH) is a recommended first step in treatment for bulimia nervosa (BN) and binge eating disorder (BED) (NICE, 2004). It remains unclear what makes some individuals more likely to respond to this form of treatment than others. Forty-eight patients participated in this study using a GSH programme for binge eating. Profiles of treatment completers and non-completers are compared, and reasons for non-completion explored. Completion of treatment was associated with significant improvements in mood, general functioning and on measures of dietary restraint, frequency of objective binge eating (OBE), laxative misuse, self-induced vomiting (SIV) and driven exercise. Improvements were maintained at follow-up. Treatment non-completers reported significantly higher pre-treatment levels of depression and weight concern, and lower levels of general health and vitality. Reasons for discontinuing treatment were related to perceptions of the GSH programme; practicalities of the programme; and readiness to change. Whilst GSH can be effective for a sub-group of patients, factors such as pre-morbid level of depression, degree of weight concern, perceptions of the programme, and readiness to change may increase the likelihood of non-completion. 相似文献
999.
Calculated sweat rates (measured by body mass changes) and voluntary fluid intakes were monitored in elite level water polo players and swimmers during normal exercise sessions to determine fluid requirements to maintain fluid balance, and the degree of fluid replacement of these athletes. Data were collected from training and competition sessions for male water polo players (n = 23) and training sessions only for swimmers (n = 20 females; n = 21 males). The calculated average sweat rate and fluid intake rate during training sessions for male water polo players was 287 ml/h and 142 ml/h, respectively, with a rate of 786 ml/h and 380 ml/h during matches. During training sessions for male swimmers, the calculated average sweat rate and fluid intake rate per kilometre was 138 ml/km and 155 ml/km, respectively; and for female swimmers, 107 ml/km and 95 ml/km. There was a wide individual variation in fluid intake and sweat loss of both water polo players and swimmers. Dehydration experienced by athletes in this study was less than typically reported for "land-based" athletes. Errors inherent in the technique used in this study are acknowledged and may be significant in the calculation of reported sweat losses and levels of fluid balance in aquatic athletes. 相似文献
1000.
Sze May Ng Mark A. Turner Carrol Gamble Mohammed Didi Suresh Victor Jessica Atkinson Vanessa Sluming Laura M. Parkes Anna Tietze Laurence J. Abernethy Alan Michael Weindling 《Pediatric radiology》2014,44(8):987-996