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DOMENICO RESTUCCIA ; SERGIO ZANINI ; MONICA CAZZAGON ; IVANA DEL PIERO ; LUCIA MARTUCCI ; GIACOMO DELLA MARCA 《Developmental medicine and child neurology》2009,51(12):991-998
Aim Event-related potentials (ERPs) obtained when focused attention is kept away from the stimulus (unnoticed stimulation) are possibly linked to automatic mismatch-detection mechanisms, and could be a useful tool to investigate sensory discrimination ability. By considering the high impact of impaired somatosensory integration on many neurological disturbances in children, we aimed to verify whether mismatch-related responses to somatosensory stimulation could be obtained in healthy children.
Method Eleven healthy participants (age range 6–11y, mean 8y 2mo, SD 1y 7mo; seven males, four females) underwent 'oddball' electrical stimulation of the right hand (80% frequent stimuli delivered to the thumb, 20% deviant stimuli delivered to the fifth finger). Data were compared with those obtained when the frequent stimuli to the thumb were omitted ('standard-omitted' protocol). ERPs were recorded at frontal, central, and parietal scalp locations. Children's overt attention was engaged by a demanding video game.
Results In the oddball protocol, deviant stimulation elicited a left central negativity at about 160ms latency, followed by a left frontal negative response at about 220ms latency. Standard-omitted traces showed only a left parietal negative response spreading to right parietal regions.
Interpretation Mismatch-related somatosensory responses can be reliably obtained in children, providing that appropriate technical contrivances are used. In clinical use, the frontal components, which are present only during the oddball protocol, could be a reliable and unequivocal neurophysiological marker of the automatic mismatch-detection mechanism. 相似文献
Method Eleven healthy participants (age range 6–11y, mean 8y 2mo, SD 1y 7mo; seven males, four females) underwent 'oddball' electrical stimulation of the right hand (80% frequent stimuli delivered to the thumb, 20% deviant stimuli delivered to the fifth finger). Data were compared with those obtained when the frequent stimuli to the thumb were omitted ('standard-omitted' protocol). ERPs were recorded at frontal, central, and parietal scalp locations. Children's overt attention was engaged by a demanding video game.
Results In the oddball protocol, deviant stimulation elicited a left central negativity at about 160ms latency, followed by a left frontal negative response at about 220ms latency. Standard-omitted traces showed only a left parietal negative response spreading to right parietal regions.
Interpretation Mismatch-related somatosensory responses can be reliably obtained in children, providing that appropriate technical contrivances are used. In clinical use, the frontal components, which are present only during the oddball protocol, could be a reliable and unequivocal neurophysiological marker of the automatic mismatch-detection mechanism. 相似文献
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Persistence of Phrenic Nerve Palsy Following 28‐mm Cryoballoon Ablation: A Four‐Year Single Center Experience 下载免费PDF全文
YUKIO SAITOH M.D. GHAZALA IRFAN M.D. GIUSEPPE CICONTE M.D. GIACOMO MUGNAI M.D. JUAN SIEIRA M.D. GIACOMO DI GIOVANNI M.D. GIANNIS BALTOGIANNIS M.D. Ph.D. GIULIO CONTE M.D. BURAK HÜNÜK M.D. ERWIN STRÖKER M.D. VEDRAN VELAGIĆ M.D. INGRID OVEREINDER M.D. CARLO DE ASMUNDIS M.D. Ph.D. GIAN‐BATTISTA CHIERCHIA M.D. Ph.D. PEDRO BRUGADA M.D. Ph.D. 《Pacing and clinical electrophysiology : PACE》2015,38(7):807-814
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FABRIZIO D'ASCENZO M.D. FRANCESCO COLOMBO M.D. UMBERTO BARBERO M.D. CLAUDIO MORETTI M.D. PIERLUIGI OMEDÈ M.D. MATTHEW J. REED M.D. GIUSEPPE TARANTINI M.D. GIACOMO FRATI M.D. JAMES J. DI NICOLANTONIO PharmD. GIUSEPPE BIONDI ZOCCAI M.D. FIORENZO GAITA M.D. 《Journal of interventional cardiology》2014,27(3):233-241
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One Year Incidence of Atrial Septal Defect after PV Isolation: A Comparison Between Conventional Radiofrequency and Cryoballoon Ablation 下载免费PDF全文
GIACOMO MUGNAI M.D. JUAN SIEIRA M.D. GIUSEPPE CICONTE M.D. MARTA SORIANO HERVAS M.D. GHAZALA IRFAN M.D. YUKIO SAITOH M.D. BURAK HÜNÜK M.D. ERWIN Ströker M.D. VEDRAN VELAGIC M.D. KRISTEL WAUTERS M.D. CLAUDIO TONDO M.D. Ph.D. GIULIO MOLON M.D. CARLO DE ASMUNDIS M.D. Ph.D. PEDRO BRUGADA M.D. Ph.D. GIAN‐BATTISTA CHIERCHIA M.D. Ph.D. 《Pacing and clinical electrophysiology : PACE》2015,38(9):1049-1057
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DI GIACOMO BE 《Minerva pediatrica》1958,10(38):950-954
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