首页 | 本学科首页   官方微博 | 高级检索  
文章检索
  按 检索   检索词:      
出版年份:   被引次数:   他引次数: 提示:输入*表示无穷大
  收费全文   401篇
  免费   44篇
  国内免费   1篇
耳鼻咽喉   4篇
儿科学   14篇
妇产科学   16篇
基础医学   39篇
口腔科学   28篇
临床医学   46篇
内科学   58篇
皮肤病学   9篇
神经病学   50篇
特种医学   16篇
外科学   35篇
综合类   9篇
一般理论   1篇
预防医学   31篇
眼科学   8篇
药学   41篇
中国医学   3篇
肿瘤学   38篇
  2024年   1篇
  2023年   5篇
  2022年   16篇
  2021年   27篇
  2020年   10篇
  2019年   20篇
  2018年   30篇
  2017年   25篇
  2016年   19篇
  2015年   7篇
  2014年   24篇
  2013年   32篇
  2012年   33篇
  2011年   36篇
  2010年   25篇
  2009年   21篇
  2008年   29篇
  2007年   24篇
  2006年   15篇
  2005年   13篇
  2004年   5篇
  2003年   6篇
  2002年   3篇
  2001年   1篇
  2000年   3篇
  1999年   4篇
  1998年   3篇
  1997年   1篇
  1996年   3篇
  1993年   1篇
  1991年   1篇
  1980年   2篇
  1973年   1篇
排序方式: 共有446条查询结果,搜索用时 0 毫秒
71.
Annals of Nuclear Medicine - Hepatotoxicity remains amongst the restricting factors of Methotrexate (MTX)-associated cancer therapy, especially in high doses of chemo-drugs or prolonged treatment....  相似文献   
72.
73.
From July to December 2003, four categories of diarrhoeagenic Escherichia coli were investigated in Tehranian children with acute diarrhoea. Stool specimens of children under 5 years of age with diarrhoea (n=200) and matched controls (n=200) without diarrhoea were studied for the presence of entero-aggregative (EAEC), enteropathogenic (EPEC), enterotoxigenic (ETEC) and Shiga toxin-producing (STEC) E. coli by PCR identification of six different genes of diarrhoeagenic E. coli. STEC isolates were typed by O157 and H7 antisera. EAEC was the most prevalent category and was found in 24% of patients with diarrhoea and 8% of controls (p<0.0001). ETEC was isolated in 15.5% of patients with diarrhoea but not in any controls ( p<0.0001), STEC in 15% of patients and 2% of controls (p<0.0001) and EPEC in 6% of patients and 5% of controls. Of 30 STEC isolates from patients with diarrhoea, seven were O157:H7 and 23 were non-O157:H7.  相似文献   
74.
Bacterial biofilms are aggregates of bacterial cells embedded in a self-produced extracellular polymeric matrix. Biofilm formation has always been considered a major challenge for sensors used in underwater measurements, and is a primary source of measurement error, especially when it comes to long-term in situ monitoring. We demonstrate the utility of lytic bacteriophages (bacterial viruses) as a non-invasive strategy for removing bacterial biofilms formed on the gas permeable membrane of electrochemical dissolved oxygen sensors. Our results show that a 4 day Pseudomonas aeruginosa biofilm with a fully developed matrix significantly affected the sensor signal and response time, decreasing the signal by 32% and increasing the response time by 94%. In addition, measurements with the biofouled membrane had a very low signal to nose ratio compared to a clean sensor membrane. A single dose of overnight phage treatment effectively removed the biofilm (as indicated by scanning electron micrographs and fluorescence images of the membrane), without the need for repeated treatments. Furthermore, the sensor signal that had plummeted by 32% for a fully biofouled membrane, was returned to the original value (7.96 ± 0.27 mg L−1) after phage treatment and the signal to noise ratio (calculated as the ratio of mean to standard deviation) increased 8 folds for a phage-treated membrane compared to a biofouled membrane. Our data indicate near complete regeneration and signal recovery for the dissolved oxygen sensor, making the biofouled sensor reusable without the use of harsh chemicals that could destroy the fragile sensor membrane.

Lytic bacteriophages can be utilized as a non-invasive method for removing bacterial biofilms formed on the surface of gas permeable membranes of dissolved oxygen sensors.  相似文献   
75.
76.
77.
78.
This study aimed to investigate the association between self-rated mental health (SRMH) and current health status of an Iranian population. A cross-sectional study was conducted on 3400 individuals selected through random sampling in Shiraz, Iran between January 2014 and March 2015. Data were gathered through face-to-face interviews. Statistical analyses were performed using the SPSS 19.0, and R.3.1.2 software was used for SCAD penalized logistic regression. The mean age of the participants was 38.5 (±?14.1 years). There were significant relationships between better SRMH and younger ages (p?<?0.001), and between better SRMH and better self-rated physical health (p?<?0.001). Individuals with poor SRMH were more likely to have signs and symptoms of medical diseases. SRMH, a component of self-rated health, was related to a variety of health problems in our study population. Therefore, paying attention to SRMH and mental well-being could be useful in making decision about implementation of preventive measures.  相似文献   
79.

Background/Objective

Genital warts are caused by human papilloma virus (HPV) and usually have no promising cure. Garlic (Allium sativum) belongs to Liliaceae family, which has a long history of medicinal use. The garlic extract had antiviral and anticarcinogenic effects and can be effective on complete resolution of cutaneous wart. The aim of this clinical study was to compare the garlic extract effect with cryotherapy in the treatment of male genital wart.

Methods

35 male patients aged 20–54 years old with clinically diagnosed genital warts who had more than two warts on both sides of genital region enrolled in the study. Cryotherapy with liquid nitrogen (?196 °C temperature) was performed for all right sided warts and 10% garlic extract was applied on all left-sided warts for 2 months.

Results

Regarding response to treatment, at the end of weeks 2, 4, 6 and 8 there was no significant difference between two groups (P > 0.05). 69.7% and 78.8% of patients showed complete clearing of the lesions in the garlic and cryotherapy groups respectively (P value, 0.39).

Conclusions

The present study revealed 10% garlic extract after 2 months duration therapy on the male genital warts had the similar effect in compare to cryotherapy.  相似文献   
80.
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号