全文获取类型
收费全文 | 549篇 |
免费 | 26篇 |
国内免费 | 5篇 |
专业分类
耳鼻咽喉 | 1篇 |
儿科学 | 26篇 |
妇产科学 | 4篇 |
基础医学 | 43篇 |
口腔科学 | 15篇 |
临床医学 | 111篇 |
内科学 | 67篇 |
皮肤病学 | 13篇 |
神经病学 | 23篇 |
特种医学 | 115篇 |
外科学 | 37篇 |
综合类 | 50篇 |
预防医学 | 27篇 |
眼科学 | 4篇 |
药学 | 26篇 |
1篇 | |
中国医学 | 2篇 |
肿瘤学 | 15篇 |
出版年
2021年 | 4篇 |
2019年 | 1篇 |
2018年 | 4篇 |
2017年 | 3篇 |
2016年 | 1篇 |
2015年 | 31篇 |
2014年 | 45篇 |
2013年 | 25篇 |
2012年 | 11篇 |
2011年 | 30篇 |
2010年 | 22篇 |
2009年 | 24篇 |
2008年 | 19篇 |
2007年 | 27篇 |
2006年 | 29篇 |
2005年 | 13篇 |
2004年 | 15篇 |
2003年 | 11篇 |
2002年 | 13篇 |
2001年 | 10篇 |
2000年 | 8篇 |
1999年 | 11篇 |
1998年 | 15篇 |
1997年 | 14篇 |
1996年 | 17篇 |
1995年 | 20篇 |
1994年 | 24篇 |
1993年 | 11篇 |
1992年 | 2篇 |
1991年 | 3篇 |
1990年 | 1篇 |
1989年 | 9篇 |
1988年 | 9篇 |
1987年 | 6篇 |
1986年 | 9篇 |
1985年 | 22篇 |
1984年 | 8篇 |
1983年 | 7篇 |
1982年 | 3篇 |
1981年 | 10篇 |
1980年 | 9篇 |
1979年 | 1篇 |
1978年 | 6篇 |
1977年 | 7篇 |
1976年 | 3篇 |
1973年 | 1篇 |
1971年 | 1篇 |
1970年 | 1篇 |
1969年 | 1篇 |
1957年 | 1篇 |
排序方式: 共有580条查询结果,搜索用时 0 毫秒
71.
目的:了解乌审旗妇女宫颈癌及癌前病变的发病现状,探讨子宫颈液基细胞学(Thinprep paptest,TCT)结合阴道镜检查的诊断价值。方法:对3 000名乌审旗妇女进行TCT筛查,对TCT阳性(细胞学TBS分类为不典型鳞状细胞以上)的妇女进行阴道镜及镜下多点活组织检查(活检),分析TCT阳性者的阴道镜检查及活检结果,比较TCT阳性者中不同年龄段患者的活检结果。结果:3 000名受检者中,TCT阳性537例(17.9%),其中经活检证实为宫颈上皮内瘤变(cervical intraepthelial neoplasia,CIN)190例(6.3%),宫颈浸润癌2例(0.07%),537例TCT阳性者中,阴道镜检查正常264例(49.2%),其中活检结果为CIN34例,阴道镜的假阴性率为12.9%,异常273例(50.8%),其中活检结果为湿疣34例,CIN或浸润癌158例,阴道镜与活检的诊断符合率达70.3%(192/273)。TCT为轻度鳞状上皮内病变、高度鳞状上皮内病变、鳞状细胞癌的病例与活检的诊断符合率分别为50.4%,88.3%和2/2,假阳性率则分别为49.6%、11%和0。537例TCT阳性者中,2030岁组、3140岁组,4147岁组的CIN检出率分别为33.7%、44.5%2、6.7%(P〈0.05)。结论:乌审旗妇女CIN的发生率高,是宫颈癌的高发人群。TCT结合阴道镜检查是较好的宫颈癌筛查手段之一。 相似文献
72.
目的 探讨抗血管紧张素Ⅱ受体1型(AT1-受体)、α1-肾上腺素受体(α1-受体)、自身抗体是否与慢性肾小球肾炎(CaN)发病有关。方法 以合成的AT1受体和α1受体多肽片段为抗原,应用酶联免疫吸附测定(ELISA)技术,检测66例CGN患者、58例高血压病患者及柏例正常人血清中抗AT1和α1受体自身抗体。结果 CGN肾功能不全组抗AT1和α1受体抗体阳性率分别为56.1%(37/66)和53.0%(36/66),高于高血压无肾损害组(分别为15.5%和12.1%)及正常对照组(分别为10%和12.5%),P〈0.01。结论 抗G蛋白偶联型受体自身抗体可能与慢性肾小球肾炎发病有关。 相似文献
73.
74.
75.
BACKGROUND: The effect of prestorage filtration on the quality of apheresis platelet concentrates stored for transfusion is undetermined. STUDY DESIGN AND METHODS: Investigation of 11 plateletpheresis components used a concurrent paired-study design. On the day of collection, each component was equally divided into two suspensions; one half was filtered, and the other half was not. Each suspension was stored for 5 days. In vitro testing was performed on the day of collection (Day 0) for cell counts and on Day 5 for measurements of lactate, glucose, blood gases, pH, platelet ATP, hypotonic stress ratio, extent of shape change in response to ADP, tissue necrosis factor alpha, interleukin 8, interleukin 1 alpha, interleukin 1 beta, interleukin 6, and platelet surface glycoproteins by flow cytometry. At the end of the 5-day period, a sample was taken from each of the two suspensions, radiolabeled with either 51Cr or 111In, and transfused concurrently. Posttransfusion samples were drawn for measurements of recovery and platelet survival and for functional assessment of the ex vivo ability of the circulating radiolabeled platelets to aggregate in response to ADP. RESULTS: The apheresis component had a mean platelet yield of 3.2 +/? 0.4 × 10(11) and a white cell yield ranging from 1 × 10(5) to 1 × 10(8), with a median of 2 × 10(7). Filtration resulted in a platelet loss of approximately 10 percent and a variable 2 to 3 log10 reduction in white cell content. No significant differences between filtered and unfiltered suspensions in paired t tests that would likely have an impact on platelet quality were observed in the in vitro tests. The in vivo recovery and survival were highly similar and not statistically different in filtered and unfiltered paired suspensions: the mean difference was 1.2 +/? 4.0 percent for recovery and 7.0 +/? 15 hours for survival. The functional assessment by aggregation to ADP showed no difference between filtered and unfiltered suspensions. A small decrease in tumor necrosis factor alpha and interleukin 8 was evident in the filtered suspension as compared to levels in the unfiltered suspensions. CONCLUSION: Prestorage white cell reduction in apheresis components resulted in WBC reduction by several log10 with no evident adverse effect on platelet viability or function. 相似文献
76.
X-linked hypophosphatemia in adults: prevalence of skeletal radiographic and scintigraphic features 总被引:3,自引:0,他引:3
The radiologic studies of 38 essentially untreated adults with X-linked hypophosphatemia (XLH) were reviewed to determine the prevalence of radiologic features, to compare the findings in men and in women, and to elucidate the natural history of the disease by comparing the findings in young, intermediate-age, and older patients. Bone-reinforcement lines were common, but no characteristic mineral mass alteration was established. Looser zones were more prevalent in older subjects. Osteoarthritis was common, occurring in the ankles, knees, feet, sacroiliac joints, and wrists. Enthesopathy was infrequent in the younger group but was present in every member of the intermediate and older groups and was often accompanied by extra ossicles. Curvatures of the lower-extremity long bones were common in all age groups. Three new skeletal alterations in XLH were found to be common: flaring of the iliac wings, trapezoidal distal femoral condyles, and alterations in talar morphology, including shortening of the talar neck and flattening of the talar dome. Technetium-99m methylene diphosphonate scintigrams of 17 subjects were often abnormal, depicting bowing deformity and focal tracer accumulation in diaphyseal cortices and in periarticular and extraarticular regions. The mean metabolic index was moderately elevated (4.0). Both radiographic and scintigraphic findings were more severe in men, consistent with hemizygosity. The natural history of untreated XLH in both sexes is characterized by the development of a variety of age-related skeletal abnormalities during adulthood. 相似文献
77.
78.
79.
80.
Breast specimen radiography: evaluation of a compression device 总被引:1,自引:0,他引:1
The irregular shape and uneven tissue thickness of excised breast specimens makes radiographic evaluation difficult, especially when calcifications are not present. Xeroradiographs before and after compression of 20 separate excised breast specimens were compared, and 17 of the same specimens were compared after compression combined with immersion in water. Specimen compression improved visibility of the lesion on average in 88% of cases, and visibility was equal in 12%. Combined compression/immersion further improved visibility of the lesion on average in 37% of cases. More significantly, evaluation of the compressed specimen led to a change in interpretation of the radiographs in 45% of cases. Compression of the specimen in specimen radiography is recommended in all cases in which pre-biopsy localization is performed. 相似文献