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91.
92.
Julien Pauchot Djamel Remache Jerome Chambert Ahmed Elkhyat Emmanuelle Jacquet 《European journal of plastic surgery》2013,36(3):185-190
After performing a V-Y advancement flap, we observed an unusually shaped necrosis, resembling a keyhole at the apex of the flap. As high closing tensions are an accepted cause of skin necrosis, we developed a mathematical model based on the finite element analysis in order to determine the stress field by simulating the mechanical behavior of human skin during suture and to explain this particular shape of necrosis. For the modeling, a planar nonlinear two-dimensional finite element model was used. The numerical simulation was carried out with Ansys® v12 software. Results are expressed in numerical and graphic form. The shape of the vertical iso-stress line for a stress equal to 18.8 kPa was similar to the necrosis observed in our clinical case. Similarities between the shape of necrosis and the calculated stress field at the apex of the V-Y advancement flap indicate the major role of skin tension in this necrosis. Finite element analysis is an original approach for describing the particular shape of a necrosis. Although many factors can be implicated in skin necrosis, the modeling confirms the role of tension in the necrosis of this particular case. Level of Evidence: Level V, risk/prognostic study 相似文献
93.
Emmanuelle Le Moigne Aurélien Delluc Cécile Tromeur Emmanuel Nowak Dominique Mottier Karine Lacut Gregoire Le Gal 《Thrombosis research》2013
The risk of recurrent venous thromboembolism (VTE) in young women after a first oestrogen contraception associated VTE episode is unknown. This uncertainty has an impact on the decision whether to stop anticoagulant treatment. Our objective was to assess the risk of recurrent VTE in women after a first VTE episode on oestrogen contraception. This was a prospective cohort study in which we consecutively enrolled between 1992 and 2011 all women under 50 years with a first objectively confirmed VTE. The incidence of recurrent VTE during follow-up after stopping anticoagulation was compared between women users and non-users of combined oral contraception (COC) at the time of index VTE. Of the 241 women aged 50 or younger seen for a first VTE and followed-up after stopping anticoagulation, there were 180 COC-users and 61 non-users. Median duration of follow-up off-anticoagulants was 66 months (interquartile range: 33–103). There were 14 recurrences in COC-users and 5 cases in non-users. No significant association was found between exposure to COC and the incidence of recurrent VTE after adjustment for age or after restricting the analysis to major unprovoked VTE: incidence rate of recurrence 17.9/1,000/year (95% CI: 9.6-33.2) in women with COC as compared with 17.6/1,000/year (95% CI: 6.6-47) with an incidence ratio of 0.7 (95% CI: 0.2-2.4, p = 0.59). The risk of recurrent VTE is low in young women after a first VTE. However, this risk is not significantly lower in women after a first VTE while exposed to combined oral contraception. 相似文献
94.
Stéphane Prange MD PhD Elise Metereau PhD Audrey Maillet PhD Hélène Klinger MPsych Emmanuelle Schmitt MPsych Eugénie Lhommée MPsych Amélie Bichon MPsych Sophie Lancelot PharmPhD Sara Meoni MD PhD Emmanuel Broussolle MD PhD Anna Castrioto MD PhD Léon Tremblay PhD Paul Krack MD PhD Stéphane Thobois MD PhD 《Movement disorders》2022,37(6):1211-1221
95.
Del Prete Eleonora Schmitt Emmanuelle Meoni Sara Fraix Valerie Castrioto Anna Pelissier Pierre Ceravolo Roberto Moro Elena 《Neurological sciences》2022,43(6):3641-3647
Neurological Sciences - In Parkinson’s disease (PD), non-motor fluctuations (NMFs), especially neuropsychiatric fluctuations, often coexist with motor fluctuations (MFs) but are often... 相似文献
96.
Bisphosphonates for preventing bone disease in kidney transplant recipients: a meta‐analysis of randomized controlled trials
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Emmanuelle B. Versele Steven Van Laecke Annemieke W. Dhondt Francis Verbeke Raymond Vanholder Wim Van Biesen Evi V. Nagler 《Transplant international》2016,29(2):153-164
An estimated 60% of kidney transplant recipients have mineral bone disease and about 0.5% break their hip within the first year after transplantation. We conducted a systematic review of benefits and harms of bisphosphonates in kidney transplant recipients. We searched CENTRAL (Issue 5, 2015) for randomized controlled trials in all languages and screened the reference list of an earlier Cochrane review. One reviewer identified the trials, extracted all data, and assessed risk of bias. Meta‐analysis used a random effects model, with results expressed as risk ratios (RR) or mean differences (MD) with 95% confidence intervals (CI). Bisphosphonates have uncertain effects on death (RR 0.45, CI 0.04–4.69) and vertebral fractures (RR 0.58, CI 0.24–1.43, I2 0%). Bisphosphonates moderately to importantly reduce the loss of vertebral bone mineral density (MD 5.98%, CI 3.77–8.18% change from baseline in g calcium/cm² at 12 months, I2 91%) and femoral bone mineral density (MD 5.57%, 3.12–8.01% change from baseline in g calcium/cm² at 12 months, I2 69%). At this stage, insufficient evidence exists to support routine use of bisphosphonates to reduce fracture risk after kidney transplantation. Data on important health outcomes are lacking, surrogate outcomes poorly reflect bone quality in kidney transplant recipients, and serious adverse events are not studied and reported systematically. 相似文献
97.
98.
Oryszczyn MP Bouzigon E Maccario J Siroux V Nadif R Wright A Kauffmann F 《The Journal of allergy and clinical immunology》2007,119(1):57-63
BACKGROUND: Delineating asthma subphenotypes is of interest to understand the cause of the disease. Few studies have addressed the interrelationships of quantitative asthma-related traits. OBJECTIVE: We sought to study the interrelationships of allergy markers and FEV(1) in relation to asthma and sex in children and adults. METHODS: Total IgE levels, skin prick test (SPT) positivity, eosinophil counts, and FEV(1) were assessed in 299 asthmatic cases (children and adults) recruited in chest clinics and 309 nonasthmatic population-based control subjects in the French Epidemiological Study on the Genetics and Environment of Asthma, Bronchial Hyperresponsiveness, and Atopy. RESULTS: Allergy parameters were significantly higher in asthmatic cases than in control subjects for children and adults and for both sexes. Sex and age modified the pattern of concordance of high IgE levels, SPT positivity, and eosinophilia among asthmatic cases, with the greatest overlap in male children (64%) and the lowest in male adults (18%). Patterns of change over the lifespan of IgE levels, eosinophil counts, and FEV(1)/height(2) varied, with the acceleration of FEV(1) decrease being particularly evident in asthmatic adults. In adult cases and control subjects, SPT positivity (particularly to indoor allergens) was significantly related to IgE levels but not to eosinophil counts. The association of eosinophil counts with IgE levels was evident only in children. Environmental factors (smoking, pets, and country living) did not alter the patterns observed. CONCLUSIONS: Each allergy-related phenotype showed a distinct relation with asthma, with the role for eosinophils being different than that for IgE levels and SPT responses. CLINICAL IMPLICATIONS: Taking age and sex into account is essential for understanding the interrelationships of the various allergy-related phenotypes to asthma status. 相似文献
99.
Rachel Sandwell Deborah Bonser Emmanuelle Hebert Katrina Kilroy Sebalda Leshabari Feddy Mwanga Agnes Mtawa Anne Wilson Amelie Moritz 《Globalization and health》2018,14(1):123
This article describes a twinning relationship between the Canadian Association of Midwives (CAM) and the Tanzania Midwives Association (TAMA). It argues that the twinning relationship strengthened both associations. The article briefly reviews the existing literature on professional associations and association strengthening to demonstrate that professional associations are a vital tool for improving the performance of healthcare workers and increasing their capacity to contribute to national and international policy-making. It then suggests that midwifery associations are particularly significant given the frequent professional marginalization of midwives. The article then describes in depth the relationship between CAM and TAMA, highlighting the accomplishments of the twinned partners, and analyzing the factors that contributed to the success of the relationship. The findings demonstrate that twinning can successfully strengthen associations, increasing their ability to support their membership, care for the public, and shape national policy-making. The article therefore proposes twinning as a successful and cost-effective model for encouraging the growth of the midwifery profession. 相似文献
100.
Julia?BaudryEmail author Hélène?Lelong Solia?Adriouch Chantal?Julia Benjamin?Allès Serge?Hercberg Mathilde?Touvier Denis?Lairon Pilar?Galan Emmanuelle?Kesse-Guyot 《European journal of nutrition》2018,57(7):2477-2488