全文获取类型
收费全文 | 2741篇 |
免费 | 217篇 |
国内免费 | 7篇 |
专业分类
耳鼻咽喉 | 5篇 |
儿科学 | 79篇 |
妇产科学 | 41篇 |
基础医学 | 485篇 |
口腔科学 | 15篇 |
临床医学 | 306篇 |
内科学 | 595篇 |
皮肤病学 | 79篇 |
神经病学 | 349篇 |
特种医学 | 62篇 |
外科学 | 233篇 |
综合类 | 5篇 |
预防医学 | 200篇 |
眼科学 | 32篇 |
药学 | 174篇 |
中国医学 | 1篇 |
肿瘤学 | 304篇 |
出版年
2024年 | 2篇 |
2023年 | 25篇 |
2022年 | 57篇 |
2021年 | 100篇 |
2020年 | 66篇 |
2019年 | 85篇 |
2018年 | 105篇 |
2017年 | 76篇 |
2016年 | 68篇 |
2015年 | 96篇 |
2014年 | 113篇 |
2013年 | 125篇 |
2012年 | 247篇 |
2011年 | 249篇 |
2010年 | 126篇 |
2009年 | 129篇 |
2008年 | 203篇 |
2007年 | 199篇 |
2006年 | 165篇 |
2005年 | 165篇 |
2004年 | 144篇 |
2003年 | 138篇 |
2002年 | 104篇 |
2001年 | 20篇 |
2000年 | 20篇 |
1999年 | 22篇 |
1998年 | 20篇 |
1997年 | 12篇 |
1996年 | 11篇 |
1995年 | 7篇 |
1994年 | 7篇 |
1993年 | 8篇 |
1992年 | 5篇 |
1991年 | 7篇 |
1990年 | 9篇 |
1989年 | 5篇 |
1988年 | 5篇 |
1987年 | 12篇 |
1986年 | 5篇 |
1985年 | 2篇 |
1975年 | 1篇 |
排序方式: 共有2965条查询结果,搜索用时 0 毫秒
101.
Thibaud Damy Vronique Benedyga Tho Pezel Emmanuelle Berthelot Jacques Gauthier Gilbert Habib Marie-Christine Iliou Jean-Franois Aupetit Guillaume Baudry Pascal De Groote Damien Logeart Laure Chaufourier Vlad Ciobotaru Franoise Pousset Florence Beauvais Fabrice Bauer Florian Zores Olivier Lairez Kevin Richard Luc Hittinger Emmanuel Teiger Charles Taieb Etienne Audureau 《Nutrients》2022,14(2)
(1) Background: There is much debate about the use of salt-restricted diet for managing heart failure (HF). Dietary guidelines are inconsistent and lack evidence. (2) Method: The OFICSel observatory collected data about adults hospitalised for HF. The data, collected using study-specific surveys, were used to describe HF management, including diets, from the cardiologists’ and patients’ perspectives. Cardiologists provided the patients’ clinical, biological, echocardiography, and treatment data, while the patients provided dietary, medical history, sociodemographic, morphometric, quality of life, and burden data (burden scale in restricted diets (BIRD) questionnaire). The differences between the diet recommended by the cardiologist, understood by the patient, and the estimated salt intake (by the patient) and diet burden were assessed. (3) Results: Between March and June 2017, 300 cardiologists enrolled 2822 patients. Most patients (90%) were recommended diets with <6 g of salt/day. Mean daily salt consumption was 4.7 g (standard deviation (SD): 2.4). Only 33% of patients complied with their recommended diet, 34% over-complied, and 19% under-complied (14% unknown). Dietary restrictions in HF patients were associated with increased burden (mean BIRD score of 8.1/48 [SD: 8.8]). (4) Conclusion: Healthcare professionals do not always follow dietary recommendations, and their patients do not always understand and comply with diets recommended. Restrictive diets in HF patients are associated with increased burden. An evidence-based approach to developing and recommending HF-specific diets is required. 相似文献
102.
103.
104.
Amlie Lombes Rmy A. Bonnin Frdric Laurent Hlne Guet-Revillet Emmanuelle Bille Vincent Cattoir Marie-Sarah Fangous Ccile Le Brun Vincent Fihman Frdric Janvier Marie-Pierre Otto Anais Potron Stphane Corvec Louise Ruffier dEpenoux Assaf Mizrahi Laurent Dortet 《Antimicrobial agents and chemotherapy》2022,66(2)
105.
106.
107.
Thomas Wirth MD MSc Louise Laure Mariani MD PhD Gaber Bergant MD Michel Baulac MD PhD Marie-Odile Habert MD Nathalie Drouot MSc Emmanuelle Ollivier MSc Alenka Hodžić PhD Gorazd Rudolf MD Patrick Nitschke MSc Gabrielle Rudolf PhD Jamel Chelly MD PhD Christine Tranchant MD PhD Mathieu Anheim MD PhD Emmanuel Roze MD PhD 《Movement disorders》2020,35(5):880-885
108.
109.
110.
Duboc H Rainteau D Rajca S Humbert L Farabos D Maubert M Grondin V Jouet P Bouhassira D Seksik P Sokol H Coffin B Sabaté JM 《Neurogastroenterology and motility》2012,24(6):513-20, e246-7
Background Irritable bowel syndrome (IBS) is a multifactorial disease for which a dysbiosis of the gut microbiota has been described. Bile acids (BA) could play a role as they are endogenous laxatives and are metabolized by gut microbiota. We compared fecal BA profiles and microbiota in healthy subjects (HS) and patients with diarrhea‐predominant IBS (IBS‐D), and we searched for an association with symptoms. Methods Clinical features and stool samples were collected in IBS‐D patients and HS. Fecal BA profiles were generated using HPLC coupled to tandem mass spectrometry. The fecal microbiota composition was assessed by q‐PCR targeting dominant bacterial groups and species implicated in BA transformation. Key Results Fourteen IBS‐D patients and 18 HS were included. The two groups were comparable in terms of age and sex. The percentage of fecal primary BA was significantly higher in IBS‐D patients than in HS, and it was significantly correlated with stool consistency and frequency. Fecal counts of all bacteria, lactobacillus, coccoides, leptum and Faecalibacterium prausnitzii were similar. There was a significant increase of Escherichia coli and a significant decrease of leptum and bifidobacterium in IBS‐D patients. Conclusions & Inferences We report an increase of primary BA in the feces of IBS‐D patients compared to HS, correlated with stool consistency and frequency. A dysbiosis of different bacterial groups was detected, some of them involved in BA transformation. As the gut microbiota is the exclusive pathway to transform primary into secondary BA, this suggests a functional consequence of dysbiosis, leading to lower BA transformation. 相似文献