全文获取类型
收费全文 | 10520篇 |
免费 | 932篇 |
国内免费 | 53篇 |
专业分类
耳鼻咽喉 | 82篇 |
儿科学 | 358篇 |
妇产科学 | 251篇 |
基础医学 | 1644篇 |
口腔科学 | 119篇 |
临床医学 | 1319篇 |
内科学 | 2220篇 |
皮肤病学 | 166篇 |
神经病学 | 1152篇 |
特种医学 | 183篇 |
外科学 | 1072篇 |
综合类 | 105篇 |
一般理论 | 16篇 |
预防医学 | 1272篇 |
眼科学 | 171篇 |
药学 | 684篇 |
中国医学 | 19篇 |
肿瘤学 | 672篇 |
出版年
2024年 | 29篇 |
2023年 | 203篇 |
2022年 | 304篇 |
2021年 | 495篇 |
2020年 | 368篇 |
2019年 | 438篇 |
2018年 | 428篇 |
2017年 | 339篇 |
2016年 | 360篇 |
2015年 | 343篇 |
2014年 | 434篇 |
2013年 | 572篇 |
2012年 | 840篇 |
2011年 | 831篇 |
2010年 | 418篇 |
2009年 | 388篇 |
2008年 | 585篇 |
2007年 | 659篇 |
2006年 | 558篇 |
2005年 | 506篇 |
2004年 | 467篇 |
2003年 | 401篇 |
2002年 | 339篇 |
2001年 | 84篇 |
2000年 | 84篇 |
1999年 | 87篇 |
1998年 | 82篇 |
1997年 | 46篇 |
1996年 | 38篇 |
1995年 | 32篇 |
1994年 | 34篇 |
1993年 | 24篇 |
1992年 | 39篇 |
1991年 | 52篇 |
1990年 | 45篇 |
1989年 | 43篇 |
1988年 | 29篇 |
1987年 | 24篇 |
1986年 | 27篇 |
1985年 | 42篇 |
1984年 | 41篇 |
1983年 | 27篇 |
1981年 | 25篇 |
1979年 | 21篇 |
1977年 | 14篇 |
1976年 | 22篇 |
1974年 | 17篇 |
1973年 | 17篇 |
1972年 | 16篇 |
1971年 | 17篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
101.
Emma Finch Jennifer Lethlean Tanya Rose Jennifer Fleming Deborah Theodoros Ashley Cameron 《Medical teacher》2018,40(3):244-252
Background: A key feature of health professionals’ training, irrespective of discipline, is the acquisition and application of clinical and communication skills. Despite this, little is known about the potential role of patient feedback on this process. This systematic review aimed to answer the question: How does feedback from patients impact upon healthcare student clinical skill development and learning?Design: Systematic review of published literature.Methods: Electronic databases were searched for studies that explored the effects of patient feedback on student learning and were published before March 2016. Eligible articles underwent methodological evaluation using the McMaster University Critical Evaluation Forms and data extraction.Results: A total of 237 articles were retrieved following searches of electronic databases and hand searches of reference lists. Twelve (7 quantitative, 2 qualitative, 3 mixed methods) studies met the inclusion criteria. Eleven studies reported that patient feedback improved students’ clinical skills.Conclusion: Minimal research has explored the impact of patient feedback on student learning. The research to date suggests that direct feedback from patients may be beneficial for the development of students’ communication and clinical skills; however, the wide variety of evaluation methods and the lack of validated tools for patients to provide feedback suggest that further exploration is warranted. 相似文献
102.
Chairs Louis-Philippe Boulet Qutayba Hamid Co-authors of sections of the document Simon L Bacon C��line Bergeron Louis-Philippe Boulet Yue Chen Anne E Dixon Pierre Ernst Qutayba Hamid Fernando Holguin Charles G Irvin R John Kimoff Sushma Komakula Catherine Laprise Kim L Lavoie Stephanie A Shore Mihaela Teodorescu Marie-Claude Vohl 《Canadian respiratory journal》2007,14(4):201-208
Asthma and obesity are frequently associated, and obesity has been considered a factor contributing to both an increase in severity of asthma and to its development. The present document summarizes the proceedings of a symposium held in Montreal, Quebec, on November 2, 2006, under the auspices of the Réseau en santé respiratoire du Fonds de la recherche en santé du Québec in collaboration with the McGill University – Strauss Severe Asthma Program, Université Laval (Quebec City) and Université de Montréal. It includes an overview of the various aspects of the relationships between asthma and obesity with regard to animal models; genetic, hormonal and physiological determinants; influence of comorbidities (eg, sleep apnea syndrome); epidemiology; clinical and psychological features; and management of asthma in the obese population. 相似文献
103.
Palmieri V Pezzullo S Arezzi E D'Andrea C Cassese S Martino S Celentano A 《International journal of cardiology》2008,127(3):390-392
Diagnostic reliability of indexations of peak exercise ST segment depression (DeltaST) for heart rate reserve (HRi) or chronotropic reserve (CR) to identify significant coronary artery disease (CAD) by cycle-ergometer exercise testing has not been evaluated previously. Exercise testing by upright cycle-ergometer (25 W/3 min) were performed in consecutive patients in primary prevention with history of exercise-related chest discomfort and cardiovascular risk factors, or with overt peripheral artery disease, with or type-2 diabetes associated with two or more additional cardiovascular risk factors. Coronary angiography was performed after the test to assess significant CAD. Three different criteria for definition of inducible myocardial ischemia were tested versus significant CAD: peak DeltaST>or=100 microV, ST/HRi>1.69 microV/bpm or ST/CR>1.76 microV/%. Diagnostic accuracy vs. CAD of DeltaST>or=100 microV, of ST/HRi>1.69 microV/bpm, and of ST/CR>1.76 microV/% were 78%, 72%, and 89% respectively; sensitivity and specificity of the three criteria were 91% and 50%, 84% and 43%, 88% and 93%, respectively. Abnormal ST/CR predicted CAD independent of risk factors, pre-test probability, and more strongly than DeltaST. Combination of ST/HRi and ST/CR criteria did not improve CAD prediction. In conclusions, in clinical setting in patients in primary prevention but with moderate-to-high pre-test probability of CAD, exercise testing by cycle-ergometry and use of ST/CR>1.76 microV/% showed elevated sensitivity and specificity, and the best accuracy for diagnosis of significant CAD. 相似文献
104.
Pathophysiology of hereditary hemochromatosis 总被引:2,自引:0,他引:2
Hereditary hemochromatosis (HH) encompasses several inherited disorders of iron homeostasis characterized by increased gastrointestinal iron absorption and tissue iron deposition. The most common form of this disorder is HFE-related HH, nearly always caused by homozygosity for the C282Y mutation. A substantial proportion of C282Y homozygotes do not develop clinically significant iron overload, suggesting roles for environmental factors and modifier genes in determining the phenotype. Recent studies have demonstrated that the pathogenesis of nearly all forms of HH involves inappropriately decreased expression of the iron-regulatory hormone hepcidin. Hepcidin serves to decrease the export of iron from reticuloendothelial cells and absorptive enterocytes. Thus, HH patients demonstrate increased iron release from these cell types, elevated circulating iron, and iron deposition in vulnerable tissues. The mechanism by which HFE influences hepcidin expression is an area of current investigation and may offer insights into the phenotypic variability observed in persons with mutations in HFE. 相似文献
105.
106.
Katsuhisa Shindo M.D. Earry E. Bacon M.D. Elizabeth J. Holmes M.D. 《Diseases of the colon and rectum》1972,15(1):57-62
Summary This is believed to be the first report of aberrant gastric and salivary glands in the anal epithelium. An anal diverticulum
and scoliosis of the lower spine were concomitant findings. 相似文献
107.
Prime K Sethi G Navaratne L Dean G Fox E Sabin C Taylor C de Ruiter A Taylor G Edwards S 《AIDS (London, England)》2003,17(2):260-262
Our findings show a high rate of loss to follow-up in HIV-positive teenagers compared with adults. Of concern is the fact that this group also have high rates of sexually transmitted infections, unprotected sex and pregnancy. There is an urgent need to examine the reasons for this and adopt strategies to minimize risk-taking behaviour and to improve access to appropriate healthcare. 相似文献
108.
Jones Brian E. Allegretti Andrew S. Pose Elisa Mara Kristin C. Ufere Nneka N. Avitabile Emma Shah Vijay H. Kamath Patrick S. Gins Pere Simonetto Douglas A. 《Digestive diseases and sciences》2022,67(2):697-707
Digestive Diseases and Sciences - Acute kidney injury is seen in approximately 30% of patients with severe alcohol-associated hepatitis (AH) and is associated with increased mortality. Controversy... 相似文献
109.
110.
Christopher C Butler Kathryn O’Brien Timothy Pickles Kerenza Hood Mandy Wootton Robin Howe Cherry-Ann Waldron Emma Thomas-Jones William Hollingworth Paul Little Judith Van Der Voort Jan Dudley Kate Rumsby Harriet Downing Kim Harman Alastair D Hay 《The British journal of general practice》2015,65(633):e217-e223
BackgroundThe prevalence of targeted and serendipitous treatment for, and associated recovery from, urinary tract infection (UTI) in pre-school children is unknown.AimTo determine the frequency and suspicion of UTI in children who are acutely ill, along with details of antibiotic prescribing, its appropriateness, and whether that appropriateness impacted on symptom improvement and recovery.MethodSystematic urine sampling from children aged <5years presenting in primary care with acute illness with culture in NHS laboratories.ResultsOf 6079 children’s urine samples, 339 (5.6%) met laboratory criteria for UTI and 162 (47.9%) were prescribed antibiotics at the initial consultation. In total, 576/7101 (8.1%) children were suspected of having a UTI prior to urine sampling, including 107 of the 338 with a UTI (clinician sensitivity 31.7%). Children with a laboratory-diagnosed UTI were more likely to be prescribed antibiotics when UTI was clinically suspected than when it was not (86.0% versus 30.3%, P<0.001). Of 231 children with unsuspected UTI, 70 (30.3%) received serendipitous antibiotics (that is, antibiotics prescribed for a different reason). Overall, 176 (52.1%) children with confirmed UTI did not receive any initial antibiotic. Organism sensitivity to the prescribed antibiotic was higher when UTI was suspected than when treated serendipitously (77.1% versus 26.0%; P<0.001). Children with UTI prescribed appropriate antibiotics at the initial consultation improved a little sooner than those with a UTI who were not prescribed appropriate antibiotics initially (3.5 days versus 4.0 days; P = 0.005).ConclusionOver half of children with UTI on culture were not prescribed antibiotics at first presentation. Serendipitous UTI treatment was relatively common, but often inappropriate to the organism’s sensitivity. Methods for improved targeting of antibiotic treatment in children who are acutely unwell are urgently needed. 相似文献