全文获取类型
收费全文 | 527篇 |
免费 | 33篇 |
国内免费 | 4篇 |
专业分类
耳鼻咽喉 | 4篇 |
儿科学 | 59篇 |
妇产科学 | 14篇 |
基础医学 | 53篇 |
口腔科学 | 35篇 |
临床医学 | 31篇 |
内科学 | 121篇 |
皮肤病学 | 10篇 |
神经病学 | 53篇 |
特种医学 | 13篇 |
外科学 | 74篇 |
综合类 | 9篇 |
预防医学 | 19篇 |
眼科学 | 30篇 |
药学 | 26篇 |
肿瘤学 | 13篇 |
出版年
2024年 | 1篇 |
2023年 | 12篇 |
2022年 | 17篇 |
2021年 | 41篇 |
2020年 | 21篇 |
2019年 | 22篇 |
2018年 | 20篇 |
2017年 | 13篇 |
2016年 | 27篇 |
2015年 | 33篇 |
2014年 | 35篇 |
2013年 | 31篇 |
2012年 | 42篇 |
2011年 | 30篇 |
2010年 | 17篇 |
2009年 | 11篇 |
2008年 | 22篇 |
2007年 | 22篇 |
2006年 | 38篇 |
2005年 | 27篇 |
2004年 | 21篇 |
2003年 | 18篇 |
2002年 | 14篇 |
2001年 | 10篇 |
2000年 | 5篇 |
1999年 | 3篇 |
1998年 | 4篇 |
1996年 | 3篇 |
1995年 | 1篇 |
1992年 | 1篇 |
1988年 | 1篇 |
1979年 | 1篇 |
排序方式: 共有564条查询结果,搜索用时 46 毫秒
21.
22.
Celebi Kocaoglu Ahmet Ozel Mustafa Cayci Ece Selma Solak 《World journal of pediatrics : WJP》2016,12(2):196-201
Background
The effects of Helicobacter pylori (H. pylori) infection on growth are a controversial issue. We investigated the effects of long-term H. pylori infection on height and weight in children.Methods
A total of 200 children of 7-18 years old suffering from dyspeptic complaints were classified into two groups: H. pylori positive and negative groups, respectively. Whether the infection was impoved was followed up while performing urea breath test, and according to exposure time to the infection, the children were further divided into group 1 (≤1.5 months), group 2 (>1.5-≤6 months) and group 3 (>6 months). Antropometric measurements were obtained and repeated every six months.Results
Mean growth velocity scores in the H. pylori positive and negative groups were 0.49±3.85 [95% confidence interval (CI): -0.21-1.18] and 1.98±4.42 (95% CI: 1-2.96), respectively. The difference between both groups was statistically significant (P=0.012). Mean growth velocity scores in groups 1, 2 and 3 were 0.96±3.84, 0.16±4.51 and -0.85±3.09, respectively. Mean growth velocity scores of group 3 were significantly lower than those of groups 0 and 1 (P=0.005 and P=0.041). The mean weight scores in group 3 were similar to those in group 2, but the scores in group 3 were significantly lower than those in group 1 (-1.75±1.05, -1.21±1.37 and -0.88±1.49, respectively).Conclusion
As the duration of exposure is prolonged in children with H. pylori infection, the negative effect of the infection on both height and weight is evident.23.
24.
Devrim Sarıbal Erkan Erdem Nazlı Ece Güngör-Ordueri Akın Usta Cemil Karakuş Meriç Karacan 《Andrologia》2020,52(2):e13481
The effects of metformin on a testicular torsion injury in adolescent rat testis after I/R were evaluated in the present study. Forty adolescent rats were divided into five groups with eight rats per group: a control group; a sham-operated group; an ischaemia group, where torsion was applied for 4 hr and testis was examined immediately after detorsion; an I/R group, where torsion was applied for 4 hr and the testis was examined 4 hr after detorsion; and an I/R + M group, where the metformin (300 mg/kg) administration was added to the identical procedures used for the I/R group. Spermatogenesis, basal membrane integrity and cleaved caspase-3 expression were assessed. The I/R + M group had a significantly higher Johnsen score than the I/R group (7.9 ± 0.1 vs. 7.5 ± 0.2; p < .001; F-value = 14.2). Failure of basal membrane integrity was highest in the ischaemia group (45 ± 5) compared to the other groups (control group, 20 ± 5; sham-operated group, 16.6 ± 2.8), but not different between the I/R + M (31.6 ± 12.5) and the I/R groups (25 ± 3.5). Cleaved caspase-3 expression was highest in the ischaemia group (73.5 ± 0.7), and significantly lower in the I/R + M group (33.4 ± 0.9) than the I/R group (58.5 ± 0.2; p < .05; F-value = 7.6). Metformin decreases testicular damage by exerting protection against the harmful effects of I/R on spermatogenesis and alleviating apoptosis in adolescent rat testis. 相似文献
25.
Sayar A Metin M Solak O Turna A Alzafer S Ece T 《Asian cardiovascular & thoracic annals》2005,13(3):280-282
Reported is the successful treatment of a 24-year-old male with adenocystic carcinoma involving the tracheal carina, in which the tumor extended along the right main bronchus across the orifice of the right upper lobe. The patient underwent a carinal resection plus right upper lobectomy and reconstruction of the carina, resulting in neither anastomotic complication nor recurrence of disease during 28 months of follow-up. 相似文献
26.
Sakar A Kaya E Celik P Gencer N Temel O Yaman N Sepit L Yildirim CA Dağyildizi L Coşkun E Dinç G Yorgancioğlu A Cimrin AH 《Tüberküloz ve toraks》2005,53(2):148-155
This study is aimed to evaluate the incidence of silicosis and the relation of it with personal and work-related factors among workers exposed to silica in ceramic factory. Workers were evaluated by respiratory symptoms, physical examination, pulmonary function and radiological findings. Occupational and Enviromental Pulmonary Disease Evaluation Questionnaire of the Turkish Thoracic Society Enviromental and Occupational Pulmonary Diseases Working Group was used. 365 of 626 workers had exposure to silica and the rest 261 were concerned as control group. There was no difference between mean age, duration of work and smoking pack year among the groups (p> 0.05). Cough and sputum rates were higher in silicosis group FEV1 and FVC values were lower in silica group but this was not statistically significant. When the two subgroups of silica group (the workers in high dust concentration and the ones in low concentration) were compared, the high concentrated group had significantly more sputum but the other symptoms and pulmonary functional parameters were not different significantly. 24 workers had parenchymal densities adjusted with pneumoconiosis. The workers with the pneumoconistic finding, had a higher mean age and longer duration of work. As a conclusion, ceramic industry has risk for silicosis. And the risk increase by time and age. 相似文献
27.
Aydın Ece Erdal Çakmak Ünal Uluca Selvi Kelekçi İlyas Yolbaş Ali Güneş Servet Yel İlhan Tan Velat Şen 《Rheumatology international》2014,34(2):207-212
The aim of this study was to determine the Mediterranean fever (MEFV) gene mutations and their clinical correlations in children with familial Mediterranean fever (FMF) in southeast Turkey. Clinical and laboratory characteristics of 147 (65 males, 82 females) consecutive children with FMF having a positive MEFV gene mutation were prospectively investigated. Patients with negative MEFV gene mutations or atypical FMF presentations and those from other regions of the country were excluded. Clinical manifestations and disease severity scores were recorded. The six most frequent MEFV mutations including M694V, V726A, R726H, P369S, E148Q and P369S were investigated by a reverse hybridization test method. The median age of study group was 9.0 years, median age at diagnosis was 7.8 years, median age at disease onset was 5.0 years, and median follow-up duration was 4.0 years. A positive family history of FMF and parent-to-offspring transmission was found in 58.5 and 42.2 % of families, respectively. The frequencies of independent alleles, with decreasing order, were E148Q (30.7 %), M694V (26.0 %), R761H (13.5 %), V726A (13.0 %), P369S (10.5 %) and M680I (6.3 %) in FMF patients. The M694V subgroup had higher mean disease severity score and longer attack duration compared with E148Q and other mutations subgroups (p < 0.05). Two patients with amyloidosis had the M694V homozygote genotype. In conclusion contrast to other regions and many other ethnicities of the world, the most frequent MEFV gene mutation was E148Q in southeast Turkey. The M694V mutation frequency was lower, and disease severity was relatively mild in FMF children of this region. 相似文献
28.
The aim of the study was to assess mean platelet volume (MPV) in children with systemic lupus erythematosus (SLE) at the active and inactive stages. Twenty children with SLE and 30 age- and gender-matched controls were enrolled. Demographic data, SLE disease activity index (SLEDAI), erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), MPV, complement 3 (C3), complement 4 (C4), urine protein (Up), and urine creatinine (Ucr) values upon reactivation and remission phases were recorded. MPV was statistically higher in patients than in controls and significantly increased in active phase compared to inactive phase (p?=?0.001). A MPV level of 8.4 fL was determined as predictive cutoff value of activation of SLE (sensitivity 75 %, specificity 90 %). MPV was positively correlated with SLEDAI (p?=?0.01, r?=?0.55), ESR (p?=?0.01, r?=?0.45), CRP (p?=?0.04, r?=?0.24), and Up/Ucr (p?=?0.01, r?=?0.45) and negatively correlated with C3 (p?=?0.02, r?=??0.36), albumin (p?=?0.01, r?=??0.63), and Hb (p?=?0.01, r?=??0.48). There was not any significant association between MPV and the histological classification of lupus nephritis (p?=?0.65). MPV might be used as an early indicator of reactivation in children with SLE. MPV seemed to be more accurate than ESR, CRP, and C3 for monitoring the disease activity in SLE. 相似文献
29.
30.
Yahya Yildiz Ece Salihoglu Sezai Celik Murat Ugurlucan Ilker Murat Caglar Fatma Nihan Turhan-Caglar Omer Isik 《Archives of Medical Science》2014,10(5):933-940