全文获取类型
收费全文 | 1130篇 |
免费 | 79篇 |
国内免费 | 9篇 |
专业分类
耳鼻咽喉 | 11篇 |
儿科学 | 72篇 |
妇产科学 | 11篇 |
基础医学 | 94篇 |
口腔科学 | 31篇 |
临床医学 | 109篇 |
内科学 | 287篇 |
皮肤病学 | 21篇 |
神经病学 | 22篇 |
特种医学 | 243篇 |
外科学 | 66篇 |
综合类 | 59篇 |
预防医学 | 70篇 |
眼科学 | 20篇 |
药学 | 41篇 |
中国医学 | 9篇 |
肿瘤学 | 52篇 |
出版年
2023年 | 2篇 |
2022年 | 2篇 |
2021年 | 7篇 |
2020年 | 6篇 |
2019年 | 14篇 |
2018年 | 14篇 |
2017年 | 12篇 |
2016年 | 10篇 |
2015年 | 25篇 |
2014年 | 40篇 |
2013年 | 65篇 |
2012年 | 35篇 |
2011年 | 33篇 |
2010年 | 40篇 |
2009年 | 63篇 |
2008年 | 33篇 |
2007年 | 50篇 |
2006年 | 31篇 |
2005年 | 28篇 |
2004年 | 20篇 |
2003年 | 15篇 |
2002年 | 20篇 |
2001年 | 13篇 |
2000年 | 14篇 |
1999年 | 15篇 |
1998年 | 78篇 |
1997年 | 53篇 |
1996年 | 63篇 |
1995年 | 44篇 |
1994年 | 49篇 |
1993年 | 44篇 |
1992年 | 9篇 |
1991年 | 5篇 |
1990年 | 11篇 |
1989年 | 39篇 |
1988年 | 27篇 |
1987年 | 25篇 |
1986年 | 19篇 |
1985年 | 12篇 |
1984年 | 16篇 |
1983年 | 15篇 |
1982年 | 14篇 |
1981年 | 20篇 |
1980年 | 13篇 |
1979年 | 8篇 |
1978年 | 9篇 |
1977年 | 16篇 |
1976年 | 8篇 |
1975年 | 11篇 |
1973年 | 2篇 |
排序方式: 共有1218条查询结果,搜索用时 15 毫秒
51.
Rapid prenatal diagnosis of beta thalassemia using DNA amplification and nonradioactive probes 总被引:3,自引:0,他引:3
We used in vitro DNA amplification by the polymerase chain reaction and nonradioactive probes for prenatal diagnosis of beta thalassemia in Chinese from the Guangdong province. Exact molecular diagnoses were made in all 20 fetuses studied over a 6-month period. We conclude that this method of prenatal diagnosis for beta thalassemia is a viable approach in many parts of the world where this disease is common. 相似文献
52.
Two patients with hairy cell leukemia with massive splenomegaly and severe pancytopenia were treated with recombinant alpha-A interferon (IFN-alpha-2a). There was no significant response to a trial of IFN- alpha-2a (11 and 20 weeks) with respect to blood counts or spleen size. Subsequent treatment with 2'-deoxycoformycin (dCF) for 8 consecutive weeks (4 mg/m2/wk) resulted in normalization of spleen size and a normalization of peripheral blood counts and bone marrow in one patient. The second patient demonstrated a reduction in spleen size and improved blood counts following 9 weeks of dCF therapy but eventually became refractory. This demonstrates that dCF is non-cross-resistant with interferon and confirms the efficacy of dCF in nonsplenectomized patients. 相似文献
53.
54.
55.
目的探讨经关节入路微创钢板固定(MIPPO)技术治疗股骨远端C型骨折的临床疗效。方法2002年4月~2005年2月,应用MIPPO技术治疗股骨远端C型骨折14例,按AO/ASIF分类:C1型3例,C2型6例,C3型5例。先行关节内骨折切开复位、松质骨螺钉固定,再行髁上部分骨折间接复位、经关节内切口插入髁支撑钢板或LISS钢板桥接固定骨折。结果12例患者获得10~32个月(平均18.4个月)随访,骨折均获愈合,愈合时间10周~12个月,平均4.6个月。按Kolmert和Wulff的评价标准:优4例,良5例,可2例,差1例,优良率为75%。结论应用MIPPO技术治疗股骨远端C型骨折实现了微创操作,具有创伤小、软组织干扰少、骨折愈合快等优点,疗效满意。 相似文献
56.
A systematic review of risk of HIV transmission through biting or spitting: implications for policy 下载免费PDF全文
Objectives
The perceived threat of HIV transmission through spitting and biting is evidenced by the increasing use of “spit hoods” by Police Forces in the UK. In addition, a draft parliamentary bill has called for increased penalties for assaults on emergency workers, citing the risk of communicable disease transmission as one justification. We aimed to review literature relating to the risk of HIV transmission through biting or spitting.Methods
A systematic literature search was conducted using Medline, Embase and Northern Lights databases and conference websites using search terms relating to HIV, AIDS, bite, spit and saliva. Inclusion and exclusion criteria were applied to identified citations. We classified plausibility of HIV transmission as low, medium, high or confirmed based on pre‐specified criteria.Results
A total of 742 abstracts were reviewed, yielding 32 articles for full‐text review and 13 case reports/series after inclusion and exclusion criteria had been applied. There were no reported cases of HIV transmission related to spitting and nine cases identified following a bite, in which the majority occurred between family (six of nine), in fights involving serious wounds (three of nine), or to untrained first‐aiders placing fingers in the mouth of someone having a seizure (two of nine). Only four cases were classified as highly plausible or confirmed transmission. None related to emergency workers and none were in the UK.Conclusions
There is no risk of transmitting HIV through spitting, and the risk through biting is negligible. Post‐exposure prophylaxis is not indicated after a bite in all but exceptional circumstances. Policies to protect emergency workers should be developed with this evidence in mind. 相似文献57.
High-dose intravenous gammaglobulin in alloimmunized platelet transfusion recipients 总被引:1,自引:1,他引:1
High-dose intravenous gammaglobulin (polyvalent immunoglobulin G) has been shown to be of benefit in some patients with immune thrombocytopenic purpura (ITP), possibly by producing reticuloendothelial system blockade. We studied this approach in patients refractory to random donor platelet transfusion using an IV IgG preparation manufactured by the Swiss Red Cross. Eleven adult patients with acute leukemia received either 0.4 g IgG/kg/d intravenously X five days (four patients) or 0.6 g/kg/d X five days (seven patients). All patients had high levels of lymphocytotoxic antibody and poor responses to random donor platelets. Except for mild headaches in two patients, there were no side effects related to the IgG infusions. All patients had significant elevations of serum IgG on the day after completion of treatment. Either random donor or partially HLA-matched platelet transfusions were administered the day after and, in some cases, during the IgG therapy. No patient had an improvement in one hour posttransfusion platelet count increments. Two additional patients received pooled platelet concentrates incubated for 30 minutes at 37 degrees C with IgG at a final concentration of 3 g% prior to transfusions. These results indicate that high-dose IgG, an extremely expensive treatment, cannot be recommended for alloimmunized adults with leukemia. 相似文献
58.
CA Gateley FRCS WG Lewis FRCS DE Sturdy MS FRCS 《International journal of clinical practice》1993,47(5):276-277
SUMMARY Clinically significant symptoms due to gastrointestinal metastases from primary lung cancers is rare. A case of life-threatening lower gastrointestinal haemorrhage secondary to metastatic squamous cell carcinoma of the lung is reported. Previous reports of such metastases are reviewed, with reference to management and prognosis. After resection of colonic metastases from squamous cell lung cancer, survival is similar to that for primary disease. It is suggested that patients with known or suspected squamous cell lung cancer presenting with lower gastrointestinal symptoms be managed as aggressively as those with no previous history of disease. 相似文献
59.
中西医结合治疗老年高脂血症 总被引:2,自引:1,他引:2
目的:探讨中西医结合治疗高脂血症的临床疗效。方法:符合高脂血症标准的老年患者120例,随机分为A、B2组各60例,A组采用益肾化淤、利湿化浊为主的中药及西药辛伐他汀片治疗;B组则单纯用辛伐他汀片治疗。治疗前及治疗4周后2组均行全套血脂水平测定。结果:与B组比较,A组血清总胆固醇(TC)及甘油三酯(TG)均明显下降,HDL明显上升(均P〈0.05);A组临床控制率明显高于B组(P〈0.05);治疗后A组患者未见肝功能损害,B组转氨酶及转肽酶轻度异常,2例。停药3个月后,A组复发率低于B组(2.2%、8.8%,P〈0.05)。结论:中西医结合治疗老年高脂血症的临床效果明显优于单一的一种治疗方法,值得临床进一步推广应用。 相似文献