全文获取类型
收费全文 | 2459篇 |
免费 | 204篇 |
国内免费 | 7篇 |
专业分类
耳鼻咽喉 | 3篇 |
儿科学 | 58篇 |
妇产科学 | 34篇 |
基础医学 | 467篇 |
口腔科学 | 32篇 |
临床医学 | 289篇 |
内科学 | 567篇 |
皮肤病学 | 68篇 |
神经病学 | 242篇 |
特种医学 | 68篇 |
外科学 | 259篇 |
综合类 | 7篇 |
一般理论 | 1篇 |
预防医学 | 139篇 |
眼科学 | 28篇 |
药学 | 161篇 |
中国医学 | 5篇 |
肿瘤学 | 242篇 |
出版年
2023年 | 29篇 |
2022年 | 43篇 |
2021年 | 97篇 |
2020年 | 55篇 |
2019年 | 92篇 |
2018年 | 99篇 |
2017年 | 62篇 |
2016年 | 74篇 |
2015年 | 73篇 |
2014年 | 128篇 |
2013年 | 136篇 |
2012年 | 246篇 |
2011年 | 237篇 |
2010年 | 137篇 |
2009年 | 113篇 |
2008年 | 162篇 |
2007年 | 179篇 |
2006年 | 169篇 |
2005年 | 147篇 |
2004年 | 136篇 |
2003年 | 98篇 |
2002年 | 75篇 |
2001年 | 4篇 |
2000年 | 3篇 |
1999年 | 7篇 |
1998年 | 26篇 |
1997年 | 7篇 |
1996年 | 4篇 |
1995年 | 4篇 |
1993年 | 3篇 |
1992年 | 1篇 |
1991年 | 1篇 |
1986年 | 1篇 |
1984年 | 1篇 |
1980年 | 1篇 |
1977年 | 1篇 |
1976年 | 2篇 |
1974年 | 2篇 |
1973年 | 1篇 |
1972年 | 2篇 |
1971年 | 1篇 |
1970年 | 1篇 |
1969年 | 2篇 |
1967年 | 2篇 |
1966年 | 1篇 |
1964年 | 2篇 |
1963年 | 1篇 |
1960年 | 1篇 |
1911年 | 1篇 |
排序方式: 共有2670条查询结果,搜索用时 15 毫秒
21.
Virginie Lambert Delphine Ladarre Feriel Fortas Philippe Durand Pierre Hervé Emmanuel Gonzales Florent Guérin Laurent Savale Valérie A. McLin Oanez Ackermann Stéphanie Franchi-Abella 《Archives of Cardiovascular Diseases》2021,114(3):221-231
Central illustration. Time of occurrence and outcome of cardiovascular disorders in patients (pts) with congenital portosystemic shunt (CPSS). Patients with normal anatomy and those with congenital heart disease (CHD) were distinguished. Heart failure (HF) was the main symptom in both the prenatal and neonatal periods, whereas portopulmonary hypertension (PPH) and hepatopulmonary syndrome (HPS) represented the major concerns beyond the first months of life. CV: cardiovascular; NAS: no additional symptoms; PH: pulmonary hypertension; RD: respiratory distress. aFetal diagnosis of CPSS. bNeonatal diagnosis of CPSS. cDiagnosis of CPSS > 1 month of age 相似文献
22.
Comments on “Evaluation and review of ways to differentiate sources of ethanol in post-mortem blood”
Hakim Florian Gicquel Thomas Allorge Delphine Gaulier Jean-michel 《International journal of legal medicine》2021,135(4):1477-1479
International Journal of Legal Medicine - 相似文献
23.
24.
Salle Sophie Sevestre Christelle Richeval Camille Hakim Florian Allorge Delphine Gaulier Jean-michel 《International journal of legal medicine》2021,135(4):1467-1470
International Journal of Legal Medicine - The detection of synthetic cannabinoid (SC) intoxication cases is challenging, even more when the involved SC identification is requested in a forensic... 相似文献
25.
Aliya Ishmukhametova Jian‐Min Chen Rafaëlle Bernard Bernard de Massy Frédéric Baudat Amandine Boyer Déborah Méchin Delphine Thorel Brigitte Chabrol Marie‐Claire Vincent Mireille Claustres Sylvie Tuffery‐Giraud 《Human mutation》2013,34(8):1080-1084
Pathogenic complex genomic rearrangements are being increasingly characterized at the nucleotide level, providing unprecedented opportunities to evaluate the complexities of mutational mechanisms. Here, we report the molecular characterization of a complex duplication–triplication rearrangement involving exons 45–60 of the DMD gene. Inverted repeats facilitated this complex rearrangement, which shares common genomic organization with the recently described duplication‐inverted triplication–duplication (DUP–TRP/INV‐DUP) events; specifically, a 690‐kb region comprising DMD exons from 45 to 60 was duplicated in tandem, and another 46‐kb segment containing exon 51 was inserted inversely in between them. Taking into consideration (1) the presence of a predicted PRDM9 binding site in the near vicinity of the junction involving two inverted L1 elements and (2) the inherent properties of X–Y chromosome recombination during male meiosis, we proposed an alternative two‐step model for the generation of this X‐linked DMD DUP–TRP/INV‐DUP event. 相似文献
26.
27.
Delphine S. Tuot Clarissa Jonas Diamantidis Cynthia F. Corbett L. Ebony Boulware Chester H. Fox Donna H. Harwood Robert A. Star Krystyna E. Rys-Sikora Andrew Narva 《Clinical journal of the American Society of Nephrology》2014,9(10):1802-1805
The National Institute of Diabetes and Digestive and Kidney Diseases–supported Kidney Research National Dialogue asked the scientific community to formulate and prioritize research objectives that would enhance understanding of kidney function and disease and improve clinical outcomes. An engaged and growing group of investigators working in type 2 translation (from clinical evidence to implementation in the community) identified barriers to improving patient care in CKD and suggested research priorities to test translational strategies that have been effective for other chronic diseases. 相似文献
28.
Chandler EM Seo BR Califano JP Andresen Eguiluz RC Lee JS Yoon CJ Tims DT Wang JX Cheng L Mohanan S Buckley MR Cohen I Nikitin AY Williams RM Gourdon D Reinhart-King CA Fischbach C 《Proceedings of the National Academy of Sciences of the United States of America》2012,109(25):9786-9791
Multipotent adipose-derived stem cells (ASCs) are increasingly used for regenerative purposes such as soft tissue reconstruction following mastectomy; however, the ability of tumors to commandeer ASC functions to advance tumor progression is not well understood. Through the integration of physical sciences and oncology approaches we investigated the capability of tumor-derived chemical and mechanical cues to enhance ASC-mediated contributions to tumor stroma formation. Our results indicate that soluble factors from breast cancer cells inhibit adipogenic differentiation while increasing proliferation, proangiogenic factor secretion, and myofibroblastic differentiation of ASCs. This altered ASC phenotype led to varied extracellular matrix (ECM) deposition and contraction thereby enhancing tissue stiffness, a characteristic feature of breast tumors. Increased stiffness, in turn, facilitated changes in ASC behavior similar to those observed with tumor-derived chemical cues. Orthotopic mouse studies further confirmed the pathological relevance of ASCs in tumor progression and stiffness in vivo. In summary, altered ASC behavior can promote tumorigenesis and, thus, their implementation for regenerative therapy should be carefully considered in patients previously treated for cancer. 相似文献
29.
30.
Bouleti C Iung B Laouénan C Himbert D Brochet E Messika-Zeitoun D Détaint D Garbarz E Cormier B Michel PL Mentré F Vahanian A 《Circulation》2012,125(17):2119-2127