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51.
M. Colevray VM. Tatard-Leitman S. Gouttard P. Douek L. Boussel 《Diagnostic and interventional imaging》2019,100(3):177-183
Introduction
The purpose of this study was to develop a convolutional neural network (CNN) to determine the extent of over-scanning in the Z-direction associated with lung computed tomography (CT) examinations.Materials and methods
The CT examinations of 250 patients were used to train the machine learning software and 100 were used to validate the results. Each lung CT examination was divided into cervical, lung, and abdominal areas by the CNN and 2 independent radiologists, and the length of each area was measured. Every part above or below the lung marks was labeled as over-scanning. The accuracy of the CNN was calculated after the training phase and agreement between CNN and radiologists was assessed using kappa statistics during the validation phase. After validation the software was used to estimate the length of each of the three areas and the total over-scanning in further 1000 patients.Results
An accuracy of 0.99 was found for the testing dataset and a very good agreement (kappa = 0.98) between the CNN and the radiologists’ evaluation was found for the validation dataset. Over-scanning was 22.8% with the CNN and 22.2% with the radiologists. The degree of over-scanning was 22.6% in 1000 lung CT examinations.Conclusion
Our study shows a substantial over estimation of the length of the area to be scanned during lung CT and thus an unnecessary patient's over-exposure to ionizing radiation. This over-scanning can be assessed easily, reliably and quickly using CNN. 相似文献52.
53.
Hematopoietic and fatty bone marrow distribution in the normal and ischemic hip: new observations with 1.5-T MR imaging 总被引:2,自引:0,他引:2
Mitchell DG; Rao VM; Dalinka M; Spritzer CE; Axel L; Gefter W; Kricun M; Steinberg ME; Kressel HY 《Radiology》1986,161(1):199-202
The conversion of hematopoietic to fatty marrow is known to correlate with physiologic decreases in intramedullary blood flow. To determine whether the chronology of conversion is altered in patients with hip ischemia, T1-weighted magnetic resonance (MR) images of the hips in 50 healthy people and 27 with documented avascular necrosis (AVN) were reviewed. The distribution of fatty (high-signal) versus hematopoietic (low-signal) marrow was noted with respect to age. All patients had fatty marrow in the femoral capital epiphysis and greater trochanter. Hematopoietic intertrochanteric marrow was seen in 95% (80 of 84) of femurs in control subjects less than 50 years old, but in only 12.5% (two of 16) of those in control subjects older than 50 years (P less than .005). Only 33% (19 of 57) of patients less than 50 years with AVN had predominantly hematopoietic intertrochanteric marrow (P less than .005). The early conversion to fatty marrow in most patients with AVN as depicted by MR imaging may be an effect of decreased vascularity of the proximal femur and may allow the identification of patients at increased risk for AVN. 相似文献
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MARCOS A. DIAS ALEXANDRE H. CAMPOS VALDIR CECHINEL FILHO ROSENDO A. YUNES JOAO B. CALIXTO 《The Journal of pharmacy and pharmacology》1995,47(10):846-851
The hydroalcoholic extract of Phyllanthus urinaria (Euphorbiaceae), substance P and substance P methyl ester all caused graded contractions in the guinea-pig urinary bladder. Responses to hydroalcoholic extract and substance P were markedly inhibited in calcium-free Krebs solution, this effect being reversed by reintroduction of calcium in the medium. The contraction in response to hydroalcoholic extract was unaffected by atropine, propranolol, prazosin, yohimbine, tetrodotoxin, w-conotoxin, nicardipine, HOE 140, guanethidine, staurosporine, phorbol ester or indomethacin, excluding the involvement of nervous mediated responses, or action via cholinergic, adrenergic, kinins, cyclo-oxygenase metabolites, protein kinase C or activation of L or N-type calcium channels. The selective NK1 tachykinin antagonist (FK 888), but not NK2 (SR 48968) antagonized substance P-induced contraction, but both drugs failed to effect Phyllanthus urinaria-induced contraction. Prolonged desensitization of guinea pig urinary bladder with capsaicin (10 μM) or preincubation of guinea-pig urinary bladder with capsazepine did not affect contraction caused by hydroalcoholic extract. Ruthenium red almost completely abolished capsaicin-induced contraction, but had no effect on hydroalcoholic extract-mediated contraction. Substance P and the hydroalcoholic extract caused marked potentiation of the twitch response in the preparations field stimulated. The facilitatory effect of substance P, but not that of hydroalcoholic extract, was prevented by the NK1 (FK 888), but not by NK2 (SR 48968) antagonist. We concluded that contraction induced by hydroalcoholic extract of Phyllanthus urinaria in the guinea pig urinary bladder involves direct action on smooth muscle and relies on the mobilization of extracellular calcium influx unrelated to activation of L- and N-type calcium channels or activation of protein kinase C mechanisms. In addition contraction caused by the hydroalcoholic extract of Phyllanthus urinaria in guinea-pig urinary bladder does not involve the activation of tachykinin or vanilloid receptors. 相似文献
58.
Papillary endolymphatic sac tumors: CT, MR imaging, and angiographic findings in 20 patients 总被引:6,自引:0,他引:6
59.
Femoral head avascular necrosis: correlation of MR imaging, radiographic staging, radionuclide imaging, and clinical findings 总被引:39,自引:0,他引:39
Mitchell DG; Rao VM; Dalinka MK; Spritzer CE; Alavi A; Steinberg ME; Fallon M; Kressel HY 《Radiology》1987,162(3):709-715
To better correlate the appearance of avascular necrosis (AVN) of the femoral head on magnetic resonance (MR) images with the stage of disease, MR images of 56 proved AVN lesions were compared with staging from corresponding radiographs (n = 56), Tc-99m scans (n = 41), and grade of symptoms (n = 28). Fractures complicating AVN were seen in 28 (50%) of 56 radiographs (radiographic stages III-V). With long repetition (TR) and echo delay (TE) times, a characteristic "double line sign" consisting of high signal intensity inside a low-intensity peripheral rim was seen in 45 lesions (80%). The central region within the rim was isointense with marrow fat on both short and long TR and TE images in 20 (71%) of 28 lesions uncomplicated by fracture (stages I-II) but in only four (14%) of 28 stage III-V lesions (P less than .001). Symptoms were least severe in lesions isointense with fat and most severe in lesions with low-signal central regions at short and long TRs and TEs. The peripheral double line sign on long TR/TE images may add specificity to the diagnosis of AVN by MR imaging. A chronologic pattern of central MR signal features is presented which may allow staging of AVN by MR imaging. 相似文献