全文获取类型
收费全文 | 1104篇 |
免费 | 104篇 |
国内免费 | 4篇 |
专业分类
耳鼻咽喉 | 5篇 |
儿科学 | 40篇 |
妇产科学 | 31篇 |
基础医学 | 132篇 |
口腔科学 | 16篇 |
临床医学 | 141篇 |
内科学 | 149篇 |
皮肤病学 | 8篇 |
神经病学 | 90篇 |
特种医学 | 38篇 |
外科学 | 235篇 |
综合类 | 32篇 |
一般理论 | 1篇 |
预防医学 | 134篇 |
眼科学 | 5篇 |
药学 | 80篇 |
中国医学 | 1篇 |
肿瘤学 | 74篇 |
出版年
2023年 | 6篇 |
2022年 | 8篇 |
2021年 | 19篇 |
2020年 | 14篇 |
2019年 | 18篇 |
2018年 | 34篇 |
2017年 | 11篇 |
2016年 | 26篇 |
2015年 | 21篇 |
2014年 | 34篇 |
2013年 | 51篇 |
2012年 | 45篇 |
2011年 | 53篇 |
2010年 | 26篇 |
2009年 | 33篇 |
2008年 | 51篇 |
2007年 | 60篇 |
2006年 | 43篇 |
2005年 | 37篇 |
2004年 | 50篇 |
2003年 | 28篇 |
2002年 | 53篇 |
2001年 | 43篇 |
2000年 | 23篇 |
1999年 | 18篇 |
1996年 | 8篇 |
1993年 | 6篇 |
1992年 | 13篇 |
1991年 | 11篇 |
1990年 | 11篇 |
1989年 | 15篇 |
1988年 | 16篇 |
1987年 | 21篇 |
1986年 | 12篇 |
1985年 | 22篇 |
1984年 | 14篇 |
1983年 | 19篇 |
1982年 | 17篇 |
1981年 | 6篇 |
1979年 | 14篇 |
1978年 | 17篇 |
1976年 | 16篇 |
1975年 | 13篇 |
1974年 | 26篇 |
1973年 | 13篇 |
1972年 | 8篇 |
1971年 | 7篇 |
1970年 | 15篇 |
1966年 | 10篇 |
1941年 | 5篇 |
排序方式: 共有1212条查询结果,搜索用时 15 毫秒
11.
T. C. Stephens V. D. Courtenay J. Mills J. H. Peacock C. M. Rose D. Spooner 《British journal of cancer》1981,43(4):451-457
The "chemosensitizing" properties of the radiosensitizer misonidazole (MISO) were examined in 2 tumour systems, murine Lewis lung carcinoma and human pancreatic adenocarcinoma xenografted into immune-suppressed mice, using a soft-agar colony assay to measure tumour-cell survival. In mice bearing Lewis lung tumour, the administration of MISO simultaneously with melphalan, cyclophosphamide. CCNU, FU or vincristine gave substantial enhancement of cytotoxicity (DEFs from 1.5 to 3.5). However, no enhancement was seen with bleomycin, VP 16-213 or cis-Pt. The same level of enhancement of cyclophosphamide effect (DEF = 2.0) was seen with both cell survival and growth delay end-points effect (DEF = 2.0) was seen with both cell survival and growth delay end-points of tumour response. Enhancement was also seen in the human tumour xenograft with melphalan, cyclophosphamide and MeCCNU, using a cell survival assay, but cis-Pt was again not enhanced. 相似文献
12.
13.
Background
HIV remains responsible for an estimated 40% of mortality in South African pregnant women and their children. To address these avoidable deaths, eligibility criteria for antiretroviral therapy (ART) in pregnant women were revised in 2010 to enhance ART coverage. With greater availability of HIV services in public health settings and increasing government attention to poor maternal-child health outcomes, this study used the patient's journey through the continuum of maternal and child care as a framework to track and document women's experiences of accessing ART and prevention of mother-to-child HIV transmission (PMTCT) programmes in the Eastern Cape (three peri-urban facilities) and Gauteng provinces (one academic hospital). 相似文献14.
Ayan Kusari MA Jessica Sprague MD Lawrence F. Eichenfield MD Catalina Matiz MD Victoria R. Barrio MD 《Pediatric dermatology》2018,35(4):494-497
Primary cutaneous aspergillosis is a rare but potentially life‐threatening disease. We present the case of a premature infant who developed primary cutaneous aspergillosis with Aspergillus niger at the site of a skin abrasion that had been treated with a purple‐colored cyanoacrylate product. The infection was treated successfully with gentle debridement of the cyanoacrylate product, followed by intravenous voriconazole and topical fluconazole. To our knowledge, this is the first reported case of primary cutaneous aspergillosis occurring at the site of cyanoacrylate‐based skin adhesive. 相似文献
15.
Establishing priorities on the range of conditions managed by UK community practitioner nurse prescribers: A modified Delphi consensus study
下载免费PDF全文
![点击此处可从《Journal of advanced nursing》网站下载免费的PDF全文](/ch/ext_images/free.gif)
16.
the mechanistic target of rapamycin(m tor) is an intracellular protein kinase that functions as an energy and nutrient sensor in the cellular microenvironment of neurons. modulation of m tor is vital when nutrient and energy sources become limited. hypoxia, traumatic brain injury, cellular energy states, and growth factors all regulate the phosphorylation and total levels of m tor in cells. alterations in the microenvironment induce transduction of signals to downstream proteins by m tor allowing for cells to make the necessary adjustments to counteract stressors and survive. progesterone, a hydrophobic steroid hormone, has been shown in studies of non-neural tissue to be a suppressor of m tor and modulator of m tor phosphorylation. our study tested the effects of progesterone on m tor expression following traumatic brain injury. c57 bl/6 mice were treated with progesterone(8 mg/kg) at 1(intraperitoneal), 6(subcutaneous), 24(subcutaneous), and 48(subcutaneous) hours post closed skull traumatic brain injury. the hippocampus was then harvested 72 hours post injury and prepared for western blot analysis. we found that progesterone significantly decreased total m tor levels in all groups compared to sham treated with vehicle. this was further confirmed by immunostaining showing decreased cytoplasmic m tor levels compared to sham. our study shows progesterone is a significant modulator of m tor levels in the hippocampus of mice following traumatic brain injury. 相似文献
17.
18.
19.
20.
Sprague Rebecca Warny Karolyne Pollock Nira Daugherty Kaitlyn Lin Qianyun Xu Hua Cuddemi Christine Barrett Caitlin Chen Xinhua Banz Alice Lantz Aude Garey Kevin W. Gonzales-Luna Anne J. Alonso Carolyn D. Galvez Javier A. Villafuerte Kelly Ciarán P. 《Digestive diseases and sciences》2021,66(10):3303-3306
Digestive Diseases and Sciences - Clostridioides difficile infection (CDI) is caused by Toxins A and B, secreted from pathogenic strains of C. difficle. This infection can vary greatly in symptom... 相似文献