全文获取类型
收费全文 | 1882篇 |
免费 | 124篇 |
国内免费 | 18篇 |
专业分类
耳鼻咽喉 | 16篇 |
儿科学 | 48篇 |
妇产科学 | 19篇 |
基础医学 | 250篇 |
口腔科学 | 200篇 |
临床医学 | 168篇 |
内科学 | 416篇 |
皮肤病学 | 38篇 |
神经病学 | 140篇 |
特种医学 | 56篇 |
外科学 | 152篇 |
综合类 | 7篇 |
预防医学 | 314篇 |
眼科学 | 32篇 |
药学 | 103篇 |
中国医学 | 20篇 |
肿瘤学 | 45篇 |
出版年
2023年 | 16篇 |
2022年 | 35篇 |
2021年 | 57篇 |
2020年 | 45篇 |
2019年 | 51篇 |
2018年 | 53篇 |
2017年 | 61篇 |
2016年 | 41篇 |
2015年 | 73篇 |
2014年 | 71篇 |
2013年 | 114篇 |
2012年 | 135篇 |
2011年 | 152篇 |
2010年 | 83篇 |
2009年 | 70篇 |
2008年 | 105篇 |
2007年 | 129篇 |
2006年 | 81篇 |
2005年 | 77篇 |
2004年 | 79篇 |
2003年 | 56篇 |
2002年 | 45篇 |
2001年 | 41篇 |
2000年 | 34篇 |
1999年 | 28篇 |
1998年 | 23篇 |
1997年 | 19篇 |
1996年 | 22篇 |
1995年 | 16篇 |
1994年 | 19篇 |
1993年 | 10篇 |
1992年 | 17篇 |
1991年 | 10篇 |
1990年 | 5篇 |
1989年 | 13篇 |
1988年 | 14篇 |
1987年 | 14篇 |
1986年 | 7篇 |
1985年 | 4篇 |
1984年 | 8篇 |
1983年 | 7篇 |
1982年 | 7篇 |
1980年 | 8篇 |
1979年 | 4篇 |
1972年 | 8篇 |
1970年 | 4篇 |
1969年 | 7篇 |
1968年 | 9篇 |
1966年 | 6篇 |
1965年 | 3篇 |
排序方式: 共有2024条查询结果,搜索用时 15 毫秒
71.
72.
Tena D Romanillos O Rodríguez-Zapata M de la Torre B Pérez-Pomata MT Viana R Chaves JM Bisquert J 《Diagnostic microbiology and infectious disease》2007,58(4):481-485
Prosthetic joint infection (PJI) due to Brucella spp. is extremely rare. We report the case of a prosthetic hip infection due to Brucella melitensis in a 51-year-old male patient. The initial presentation was a gluteal abscess. There was radiographic evidence of implant loosening. The patient was cured after prolonged treatment with streptomycin, rifampicin, and doxycycline, followed by 2-stage exchange of the prosthesis. Brucella spp. should be considered in the differential diagnosis of PJI in countries where brucellosis is endemic. The review of all cases previously reported shows that a conservative approach using antibiotics alone can be followed in patients without signs of implant loosening. In contrast, prolonged antibiotic treatment and prosthetic joint revision should be considered in patients with evidence of implant loosening. 相似文献
73.
de Oliveira Assunção Flávia Fernanda Nascimento Érika Chaves Lucas da Silva Alessandro Márcio Hakme Martinez Roberto de Jesus Guirro Rinaldo Roberto 《Lasers in medical science》2022,37(5):2439-2447
Lasers in Medical Science - Photobiomodulation has been used to inactivate bacterial growth, in different laser or LED protocols. Thus, the aim of this study was to verify the inhibition of... 相似文献
74.
Fernanda Gabriela Fumuso Susana Marí Giuliano Graciela Chaves Deborah M. Neild Marcelo Horacio Miragaya Mariana LucÍa Bertuzzi Maria Ignacia Carretero 《Andrologia》2020,52(6):e13597
Seminal plasma is intimately connected to sperm physiology and particularly in South American Camelids, has demonstrated to be involved in multiple physiological reproductive events. Different percentages of seminal plasma (0%, 10% and 50%) were added to thawed llama semen samples with the objective of evaluating the interaction with cryopreserved sperm over time (0, 1.5 and 3 hr at 37°C). A total of 20 ejaculates from five adult llama males (n = 5; r = 4) were evaluated. A significant decrease in sperm motility, membrane function and live sperm was observed in all thawed samples (0%, 10% and 50%) at 0 hr when compared to raw semen. Neither morphology nor chromatin condensation was altered in all thawed samples (p > .05), but a significant increase in the percentage of spermatozoa with fragmented DNA was observed after thawing all samples versus raw semen. When evaluating thawed samples over time, a significant decrease of motility and membrane function was observed, while the percentages of total live sperm were preserved over the 3 hr of incubation in all final concentrations evaluated. To conclude, the addition of 10% or 50% of seminal plasma was incapable of preserving motility or membrane function of frozen-thawed llama sperm during 3 hr of incubation. 相似文献
75.
76.
77.
Graft-versus-host disease (GVHD) is currently encountered after bone marrow transplantation and transfusion. GVHD associated with transfusion (TA-GVHD) in apparently immunocompetent recipients has been recently reported with increasing frequency. A consistent finding in many of these cases is that the recipient received blood from a donor homozygous for one of the recipient's HLA haplotypes. However, the observed frequency of TA-GVHD is much lower than the estimated probability of this donor/recipient combination. The potential role of recipient immune responses in controlling TA-GVHD was investigated using an analogous murine model in which GVHD is induced by the injection of parental lymphoid cells into unirradiated F1 hybrid recipients. The effect of various immune manipulations of the recipient of GVHD induction was assessed by determining the number of donor lymphoid cells required to induce GVHD responses. Whereas depletion of recipient CD4+ cells increased the number of donor cells needed to induce GVHD, depletion of recipient CD8+ and natural killer cells resulted in fewer donor cells being needed to induce a GVHD response. These studies suggest a central role for functioning recipient CD8 and natural killer cells in the down-regulation of TA-GVHD development in recipients. 相似文献
78.
Cristiane Maria Pinto Diniz Tiago Lopes Farias Mayane Carneiro Alves Pereira Caio Breno Reis Pires Luciana Soares Lages Gonçalves Patrícia Chaves Coertjens Marcelo Coertjens 《International journal of occupational medicine and environmental health》2014,27(2):216-223
Objectives
The aim of this study was to verify and analyze the existence of chronic adaptations of lung function in free-diving fishermen whose occupation is artisanal fishing.Material and Methods
This was a cross-sectional study involving 11 breath-hold diving fishermen and 10 non-breath-hold diving fishermen (control) from the village of Bitupitá in the municipality of Barroquinha (Ceará — Brazil). Anthropometric measurements, chest and abdominal circumferences as well as spirometric and respiratory muscle strength tests were conducted according to the specifications of the American Thoracic Society/European Respiratory Society (ATS/ERS). In order to compare the measured values versus the predicted values, Student t test was used in the case of parametric test and Wilcoxon test in the case of nonparametric test. To compare the inter-group means Student t test was used for parametric test and Mann-Whitney test for the nonparametric one. The level of significance was set at α = 5%.Results
The forced vital capacity (FVC) (4.9±0.6 l vs. 4.3±0.4 l) and forced expiratory volume in 1 s (FEV1) (4.0±0.5 l vs. 3.6±0.3 l) were, respectively, higher in the group of divers compared to the control group (p ≤ 0.05). Furthermore, in the group of free divers, the measured FVC, FEV1 and FEV1/FVC ratios were significantly greater than the predicted ones. No differences were found between the measured respiratory pressures.Conclusions
These results indicate that breath-hold diving seems to produce chronic adaptations of the respiratory system, resulting in elevated lung volumes with no airway obstruction. 相似文献79.
Michael A. Jhung Tiffany D'Mello Alejandro Pérez Deborah Aragon Nancy M. Bennett Tara Cooper Monica M. Farley Brian Fowler Stephen M. Grube Emily B. Hancock Ruth Lynfield Craig Morin Arthur Reingold Patricia Ryan William Schaffner Ruta Sharangpani Leslie Tengelsen Ann Thomas Diana Thurston Kimberly Yousey-Hindes Shelley Zansky Lyn Finelli Sandra S. Chaves 《American journal of infection control》2014
80.
Aladdin H. Shadyab PhD JoAnn E. Manson MD DrPH Juhua Luo PhD Bernhard Haring MD MPH Nazmus Saquib PhD Linda G. Snetselaar RD PhD LD Jiu-Chiuan Chen MD ScD Erik J. Groessl PhD Sylvia Wassertheil-Smoller PhD Yangbo Sun MD PhD Lauren Hale PhD Meryl S. LeBoff MD Andrea Z. LaCroix PhD 《Journal of the American Geriatrics Society》2020,68(9):1970-1978