首页 | 本学科首页   官方微博 | 高级检索  
文章检索
  按 检索   检索词:      
出版年份:   被引次数:   他引次数: 提示:输入*表示无穷大
  收费全文   229775篇
  免费   35684篇
  国内免费   2634篇
耳鼻咽喉   6070篇
儿科学   7382篇
妇产科学   4055篇
基础医学   13415篇
口腔科学   3988篇
临床医学   33557篇
内科学   63935篇
皮肤病学   8538篇
神经病学   21803篇
特种医学   8629篇
外国民族医学   4篇
外科学   52695篇
综合类   1161篇
现状与发展   72篇
一般理论   81篇
预防医学   14945篇
眼科学   4851篇
药学   6079篇
中国医学   212篇
肿瘤学   16621篇
  2024年   717篇
  2023年   5162篇
  2022年   1715篇
  2021年   4529篇
  2020年   6783篇
  2019年   3622篇
  2018年   9404篇
  2017年   8610篇
  2016年   9754篇
  2015年   10003篇
  2014年   17696篇
  2013年   18870篇
  2012年   10874篇
  2011年   11373篇
  2010年   13285篇
  2009年   16652篇
  2008年   10765篇
  2007年   9326篇
  2006年   11519篇
  2005年   8894篇
  2004年   7940篇
  2003年   6505篇
  2002年   6423篇
  2001年   4621篇
  2000年   3787篇
  1999年   4069篇
  1998年   4405篇
  1997年   4062篇
  1996年   3891篇
  1995年   3720篇
  1994年   2405篇
  1993年   1999篇
  1992年   1926篇
  1991年   1887篇
  1990年   1455篇
  1989年   1563篇
  1988年   1370篇
  1987年   1204篇
  1986年   1203篇
  1985年   1066篇
  1984年   1054篇
  1983年   951篇
  1982年   1040篇
  1981年   919篇
  1980年   851篇
  1979年   576篇
  1978年   631篇
  1977年   687篇
  1975年   526篇
  1974年   499篇
排序方式: 共有10000条查询结果,搜索用时 0 毫秒
101.
102.
MICHELLE EHRLICH  MD    JAGGI RAO  MD    ANJU PABBY  MD    MITCHEL P. GOLDMAN  MD 《Dermatologic surgery》2006,32(5):618-625
BACKGROUND AND OBJECTIVE: Facial rhytides are a common cosmetic concern. Surgical treatment effects dramatic improvement; however, the associated risk and cost may be prohibitive. Recent focus is on developing topical products containing biologically active ingredients for at-home therapy. Our study examines the effects of a topical cream containing transforming growth factor-beta(1) (TGF-beta(1)), l-ascorbic acid, and Cimicifuga racemosa extract (CRS) (Topix Pharmaceuticals, North Amityville, NY, USA). MATERIALS AND METHODS: In the first arm of the study, 12 subjects were randomized to apply CRS to the left or right side of their face and a cream containing l-ascorbic acid and C. racemosa in silicone base (vitamin C [Vit C]) to the contralateral side twice daily for 3 months. In the second arm of the study, 20 subjects were randomized to apply CRS to the left or right side of their face and Tissue Nutrient Solution Recovery Complex (TNS) (SkinMedica, Carlsbad, CA, USA), a product containing a variety of growth factors including VEGF, PDGF-A, G-CSF, HGF, IL-6, IL-8, and TGF-beta(1) (Nouricel-MD) without l-ascorbic acid, C. racemosa extract, or silicone base, to the contralateral side of their face twice daily for 3 months. Digital photographs were scored by study-blinded physicians, and self-assessments were completed by all subjects at baseline and at the conclusion of the protocol. RESULTS: CRS and TNS were well tolerated, and all subjects completed the 3-month protocol for the CRS versus Vit C arm of the study. Physicians rated success in facial wrinkling scores on the CRS-treated side of the face for 27 of 31 subjects. Responders showed, on average, 21.7% improvement in physician-rated wrinkle scores. The mean improvement in the group of 31 patients as a whole was 12%. Eighteen of 31 subjects reported a noticeable improvement on their CRS-treated side. Both CRS and TNS demonstrate significant success between baseline and 3-month scores, and both growth factor products are superior to Vit C. Patients preferred CRS over TNS. CONCLUSION: CRS is effective in minimizing the appearance of facial rhytides. The success of the CRS product is largely attributable to the incorporation of TGF-beta(1).  相似文献   
103.
104.
105.
106.
107.
108.
109.
Background contextLarge, prominent osteophytes along the anterior aspect of the cervical spine have been reported as a cause of dysphagia. Improvement of swallowing after surgical resection has been reported in a few case reports with short-term follow-up. The current report describes outcomes of a series of five patients with surgical treatment for this rare disorder, with a long-term follow-up.PurposeTo study the clinical and radiographic outcomes of a case series of patients surgically treated for dysphagia secondary to cervical diffuse idiopathic skeletal hyperostosis (DISH).Study designRetrospective review of a case series.Patient sampleFive cases from a University Hospital.Outcome measuresClinical and imagenological follow-up.MethodsThe records of five patients with dysphagia who had undergone anterior surgical resection of prominent osteophytes secondary to DISH were reviewed. Extrinsic esophageal compression secondary to anterior cervical osteophytes was radiographically confirmed via preoperative barium esophagogram swallowing study. All patients underwent anterior cervical osteophytes resection without fusion. Postoperatively, patients were followed-up clinically and radiographically with routine lateral cervical radiographs.ResultsPreoperative esophagogram showed that the esophageal obstruction was present at one level in three cases and two levels in two cases. The C3–C4 level was involved in three cases, C4–C5 in three cases, and C5–C6 in one case. There were no postoperative complications, including recurrent laryngeal nerve palsy, wound infection, or hematomas. All patients had resolution of dyphagia soon after surgery (within 2 weeks). Postoperative radiographs demonstrated complete removal of osteophytes. At final follow-up, ranging from 1 to 9 years (average 59.8 months, median 53 months), no patients reported recurrence of dysphagia. Final radiographic examination demonstrated minimal regrowth of the osteophytes.ConclusionsAlthough rarely indicated, surgical resection of anterior cervical osteophytes from DISH causing dyphagia produces good clinical and radiographical outcomes. After thorough evaluation to rule out other intrinsic or extrinsic causes of swallowing difficulty, surgical treatment of this uncommon condition might be considered.  相似文献   
110.
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号