全文获取类型
收费全文 | 33821篇 |
免费 | 2364篇 |
国内免费 | 110篇 |
专业分类
耳鼻咽喉 | 264篇 |
儿科学 | 1343篇 |
妇产科学 | 1015篇 |
基础医学 | 4598篇 |
口腔科学 | 530篇 |
临床医学 | 4306篇 |
内科学 | 6397篇 |
皮肤病学 | 650篇 |
神经病学 | 3679篇 |
特种医学 | 741篇 |
外科学 | 3288篇 |
综合类 | 352篇 |
一般理论 | 33篇 |
预防医学 | 3985篇 |
眼科学 | 592篇 |
药学 | 1972篇 |
中国医学 | 59篇 |
肿瘤学 | 2491篇 |
出版年
2024年 | 40篇 |
2023年 | 258篇 |
2022年 | 470篇 |
2021年 | 940篇 |
2020年 | 586篇 |
2019年 | 970篇 |
2018年 | 1045篇 |
2017年 | 741篇 |
2016年 | 849篇 |
2015年 | 896篇 |
2014年 | 1247篇 |
2013年 | 1831篇 |
2012年 | 2708篇 |
2011年 | 2785篇 |
2010年 | 1535篇 |
2009年 | 1283篇 |
2008年 | 2230篇 |
2007年 | 2407篇 |
2006年 | 2326篇 |
2005年 | 2192篇 |
2004年 | 1950篇 |
2003年 | 1804篇 |
2002年 | 1733篇 |
2001年 | 254篇 |
2000年 | 211篇 |
1999年 | 251篇 |
1998年 | 337篇 |
1997年 | 302篇 |
1996年 | 232篇 |
1995年 | 199篇 |
1994年 | 160篇 |
1993年 | 196篇 |
1992年 | 126篇 |
1991年 | 103篇 |
1990年 | 91篇 |
1989年 | 95篇 |
1988年 | 90篇 |
1987年 | 49篇 |
1986年 | 57篇 |
1985年 | 49篇 |
1984年 | 59篇 |
1983年 | 56篇 |
1982年 | 60篇 |
1981年 | 51篇 |
1980年 | 58篇 |
1979年 | 41篇 |
1978年 | 44篇 |
1977年 | 36篇 |
1976年 | 32篇 |
1974年 | 30篇 |
排序方式: 共有10000条查询结果,搜索用时 9 毫秒
41.
Prediction of Remission of Acute Posttraumatic Stress Disorder in Motor Vehicle Accident Victims 总被引:1,自引:0,他引:1
Edward B. Blanchard Edward J. Hickling Catherine A. Forneris Ann E. Taylor Todd C. Buckley Warren R. Loos James Jaccard 《Journal of traumatic stress》1997,10(2):215-234
One hundred forty five individuals who sought medical attention as a result of a motor vehicle accident (MVA), and who were initially assessed 1 to 4 months post-MVA, were followed up prospectively for 6 months to determine how many of the 55 with posttraumatic stress disorder (PTSD) and the 43 with sub-syndromal PTSD would remit and what variables would predict remission. Thirty (55%) of those with initial PTSD had remitted at least in part by 6 months while 67% of those with sub-syndromal PTSD had remitted (and 5% had worsened). Four variables, including severity of initial symptoms, degree of initial physical injury, relative degree of physical recovery by 4 months and whether a close family member suffered a trauma during the follow-up interval, combined to classify 6-month clinical status of 84% of those with initial PTSD secondary to MVAs. 相似文献
42.
Giedd Jay N.; Snell John W.; Lange Nicholas; Rajapakse Jagath C.; Casey B. J.; Kozuch Patricia L.; Vaituzis A. Catherine; Vauss Yolanda C.; Hamburger Susan D.; Kaysen Debra; Rapoport Judith L. 《Cerebral cortex (New York, N.Y. : 1991)》1996,6(4):551-559
Brain magnetic resonance images (MRI) of 104 healthy childrenand adolescents, aged 418, showed significant effectsof age and gender on brain morphometry. Males had larger cerebral(9%) and cerebellar (8%) volumes (P < 0.0001 and P = 0.008.respectively), which remained significant even after correctionfor height and weight After adjusting for cerebral size, theputamen and globus pallidus remained larger in males, whilerelative caudate size was larger in females. Neither cerebralnor cerebellar volume changed significantly across this agerange. Lateral ventricular volume increased significantly inmales (trend for females), with males showing an increase inslope after age 11. In males only, caudate and putamen decreasedwith age (P = 0.007 and 0.05, respectively). The left lateralventricles and putamen were significantly greater than the rightP = 0.01 and 0.0001, respectively). In contrast, the cerebralhemispheres and caudate showed a highly consistent right greater-than-leftasymmetry (P < 0.0001 for both). All volumes demonstrateda high degree of variability. These findings highlight gender-specificmaturational changes of the developing brain and the need forlarge gender-matched samples in pediatric neuropsychiatric studies. 相似文献
43.
44.
45.
Richard Simpson Catherine Kennedy Hugh Carmalt Brian McCaughan David Gillett 《ANZ journal of surgery》1997,67(10):717-719
Background : A patient with a solitary pulmonary metastasis who had breast cancer in the past may benefit from pulmonary resection. Methods : Between 1984 and 1996, 17 patients underwent metastatectomy for metastatic breast cancer. There were 15 females and two males whose average age was 59 (range: 40–74 years). The median tumour-free interval after the primary breast-cancer operation was 5.1 years (range: 8 months-18.2 years). Sixteen patients had complete resections, which included six lobectomies and 10 lesser resections. Results : The postoperative mortality was nil and the morbidity rate was 6%. Follow-up was complete in all patients. Recurrent disease developed in four patients and two patients died of their disease. The 5-year survival was 62%. Conclusion : An aggressive surgical approach is warranted in patients with isolated resectable pulmonary metastases from breast cancer. 相似文献
46.
47.
Mapping of α- and β-globin genes on Antarctic fish chromosomes by fluorescence in-situ hybridization
Eva Pisano Ennio Cocca Federico Mazzei Laura Ghigliotti Guido di Prisco H. William Detrich III Catherine Ozouf-Costaz 《Chromosome research》2003,11(6):633-640
The pathways and mechanisms of genomic change that have led to the peculiar haemoglobinless phenotype of the white-blooded
Antarctic icefishes (16 species in the family Channichthyidae) constitute an important model for understanding the rapid diversification
of the Antarctic notothenioid fish flock. To provide complementary structural information on genomic change at globin-gene
loci in Antarctic fish species, cytogenetic studies and in-situ chromosomal mapping have been undertaken. Using a DNA probe containing one α- and one β-globin gene from the embryonic/juvenile
globin gene cluster of the red-blooded species Notothenia coriiceps, we mapped the cluster on the chromosomes of Antarctic teleosts by fluorescence in-situ hybridization. As anticipated on the basis of its molecular organization, the cluster was located on a single chromosome
pair in all of the red-blooded fish species probed (N. coriiceps, N. angustata, Trematomus hansoni, T. pennellii). In contrast, the α/β-globin probe did not recognize complementary sequences on the chromosomes of the white-blooded species
Chionodraco hamatus and Channichthys rhinoceratus. These results represent the first example of chromosomal mapping of embryonic/juvenile globin genes in teleostean fishes.
Beyond its relevance to the evolutionary history of Antarctic notothenioids, this work contributes to our understanding of
the evolution of the chromosomal loci of globin genes in fishes and other vertebrates.
This revised version was published online in July 2006 with corrections to the Cover Date. 相似文献
48.
49.
Mohand Mesbah Ilka Nemere Petros Papagerakis Jean-Raphael Nefussi Silvana Orestes-Cardoso Catherine Nessmann Ariane Berdal 《Journal of bone and mineral research》2002,17(9):1588-1596
The calciotropic hormone 1,25-dihydroxyvitamin D3 [1,25(OH)2D3] has been established to control skeletal tissue formation and biomineralization via the regulation of gene expression. This action involves the well-characterized nuclear 1,25(OH)2D3 receptor. However, it has been recognized that several cellular responses to 1,25(OH)2D3 may not to be related to the exclusive nuclear receptor. Indeed, this secosteroid is able to generate rapid responses that have been proposed to be mediated by interactions of the ligand, which is a putative cell membrane-associated rapid-response steroid (MARRS) binding protein for 1,25(OH)2D3 [1,25D3-MARRS]. The nongenomic pathway of 1,25(OH)2D3 was studied here in detail by immunolocalization of the 1,25D3-MARRS during the specific context of human prenatal development. Western blotting with proteins extracted from 4 week- to 27-week-old embryos was performed, evidencing a 65-kDa molecular species recognized by antibody Ab 099 generated against synthetic peptides corresponding to the N terminus of the 1,25D3-MARRS from chick intestinal basolateral membranes. Based on this biochemical conservation of protein in the human species, the temporospatial expression patterns were established in the craniofacial skeleton at the same ages. Comparative analysis was performed in teeth and bones from early morphogenesis to terminal cell differentiation and extracellular biomineralization. The data show the potential implication of 1,25D3-MARRS in the heterogeneous cell population including ameloblasts, odontoblasts, osteoblasts, and osteoclasts. The epithelial-mesenchymal cascade related to odontogenesis was coincident with a sequence of up- and down-regulation of immunoreactive 1,25D3-MARRS. Biomineralization was associated with a striking up-regulation in the adjoining secretory cells in all tissues. Finally, osteoclasts appeared also to express the 1,25D3-MARRS during these early phases of bone modeling. Previously obtained data of the nuclear vitamin D receptor (VDR) expression and this study on 1,25D3-MARRS suggest the existence of cross-talk between the genomic and nongenomic pathways during human development. 相似文献
50.