A CORRELATIVE STUDY OF MATERNAL HAEMOGLOBIN AND BIRTH WEIGHT

This prospective, cross sectional population study was carried out to determine the relationship between maternal haemoglobin concentration and birth weight in different socioeconomic groups in a tertiary care teaching hospital. 500 cases each from two teaching hospitals about whom information on socioeconomic status, haemoglobin concentration and birth weight was known were included in the study. This was a stratified random study based on the preselected inclusion and exclusion criteria. 149 (14.9%) women belonged to upper socioeconomic group, 119 (11.9%) to upper middle, 125 (12.5%) to lower middle, 90 (9.0%) to upper lower and 517 (51.7%) to lower group. Mean haemoglobin level was found to be lower in low socioeconomic group as compared to high socioeconomic group and was statistically significant (F value of 18.2521 & p 0.000). The lowest Hb level was 4.0g/dl and highest was 15.0g/dL Majority of pregnant women (89.3%) had their lowest haemoglobin level during the second trimester as compared to first trimester (0.8%) and third trimester (9.9%). The mean birth weight in upper socioeconomic group was 2.7508 kg, 2.7556 kg in upper middle group, 2.8802 kg in lower middle group, 2.7876 kg in upper lower group and 2.7515 in lower socioeconomic group. By analysis of variance test it was found that the mean birth weight did not vary significantly between different socioeconomic groups with an F value of 1.3398 and p value of 0.2450. The correlation analysis of haemoglobin concentration with birth weight suggested that for every rise of haemoglobin concentration by 1.0g/dl the birth weight reduced by 03839 kg (highly significant p < 0.001). In the present study there was significant inverse relationship of maternal haemoglobin concentration to birth weight Results are in agreement with the hypothesis that a higher blood viscosity is a risk factor for sub optimal placenta-perfusion.KEY WORDS: Birth weight, Maternal haemoglobin     

重症病人的贫血和红细胞输注

简介 重症病人的定义并不是很明确,但大多数临床医生指的重症病人是那些伴有器官衰竭的急性病人。在英国,伴有多器官衰竭的病人在ICU(重症监护室)医治。贫血是重症病人的常见并发症。在ICU内,对贫血的治疗是输注异体红细胞。除禁止输血治疗的病人外,进入ICU的患者大概有40％接受过红细胞输注。输血实际操作过程中存在的多种不确定因素,直接关系到输血的安全性、有效性及输血指征。本文集中讨论以下三方面的问题: