Epidemiologic investigations of bioterrorism-related anthrax,New Jersey, 2001

At least four Bacillus anthracis-containing envelopes destined for New York City and Washington, D.C. were processed at the Trenton Processing and Distribution Center (PDC) on September 18 and October 9, 2001. When cutaneous anthrax was confirmed in a Trenton postal worker, the PDC was closed. Four cutaneous and two inhalational anthrax cases were identified. Five patients were hospitalized; none died. Four were PDC employees; the others handled or received mail processed there. Onset dates occurred in two clusters following envelope processing at the PDC. The attack rate among the 170 employees present when the B. anthracis-containing letters were sorted on October 9 was 1.2%. Of 137 PDC environmental samples, 57 (42%) were positive. Five (10%) of 50 local post offices each yielded one positive sample. Cutaneous or inhalational anthrax developed in four postal employees at a facility where B. anthracis-containing letters were processed. Cross-contaminated mail or equipment was the likely source of infection in two other case-patients with cutaneous anthrax.     

人轮状病毒G2和G3型主要中和抗原VP7基因在重组腺病毒中的表达

目的 研究我国G2和G3型轮状病毒主要中和抗原VP7基因在重组腺病毒中的表达。方法 在前期成功表达Gl型VP7的基础上，选用我国G2和G3型主要流行株97S43和97S48 VP7基因，用非复制型腺病毒载体对上述基因进行表达。结果 获得了表达我国G2型和G3型人轮状病毒流行株VP7基因的非复制型重组腺病毒rvAdG2VP7和rvAdG3VP7，应用PCR及Southem blot技术证实在重组腺病毒中整合有轮状病毒G2型VP7和G3型VP7基因，RT-PCR证明重组腺病毒在感染的293细胞内均能有效地转录插入基因，Western blot检测到轮状病毒VP7基因的表达。结论 这一工作为进一步进行动物实验，发展多价轮状病毒疫苗打下了基础。     

1950～2002年昆山市急性传染病的流行趋势

目的 :探讨昆山市 195 0～ 2 0 0 2年急性传染病流行趋势 ,为研究制定防病对策提供依据。方法 :运用描述流行病学方法分析急性传染病的发病率、死亡率变化趋势。结果 :平均发病率、死亡率大幅度下降、大多数传染病得到有效控制 ,其中 2 0世纪 5 0～ 6 0年代以自然疫源性地方病为主 ,占总发病数的 4 4 .0 4 %～ 6 5 .0 8% ,70年代以呼吸道疾病为主 ,占总发病数的 5 5 .11% ,80～ 90年代以肠道传染病为主 ,占总发病数的 77.2 7%～ 77.89% ,性传播疾病自 1990年发病率呈上升趋势 ,5 0年代发病居前 5位的疾病是疟疾、麻疹、痢疾、百日咳、流行性感冒 ,而近 5年则为性病、肝炎、痢疾、肺结核、伤寒。结论 :该市急性传染病疫情出现新的特点 ,应及时制定科学的防制对策 ,加强预防和监测力度。     

2015年1月中国部分法定传染病疫情动态摘抄

<正>麻疹四川省:2015年1月全省报告519例。报告病例数较2014年同期上升5666.67%。报告病例数居前4位的地市为遂宁市、凉山州、南充市和达州市。重庆市:2015年1月全省报告286例。报告病例数较上月上升12.16%,较2014年同期上升9433.33%。报告病例数居前的县为酉阳县,占10.84%。湖南省:2015年1月全省报告78例。报告病例数较上月上升86%,较2014年同期上升160%。报告病例数居前5位的地市为邵阳、岳阳、衡阳、     

2007年2月份中国甲乙丙类传染病疫情动态简介

National Data of Class A,B and C Infectious Diseases in February2007病名Disease死亡数(1)Death number本月Feb.去年同月Last Feb.本年累计Cum2007本月Feb.去年同月Last Feb.本年累计Cum2007去年累计Cum2006鼠疫Plague-------霍乱Cholera-------传染性非典型肺炎SARS-----     

2007年6月份中国甲乙丙类传染病疫情动态简介

病名Disease死亡数(1)Death number本月June去年同月Last June本年累计Cum2007本月June去年同月Last June本年累计Cum2007去年累计Cum2006鼠疫Plague-------霍乱Cholera-------传染性非典型肺炎SARS-------艾滋病AIDS7237144237102142603613肝炎Viral Hepatitis133016126011766     

2008年7月中国部分法定传染病疫情动态摘抄

安徽：7月14-20日，报告手足口病例688例，比上周减少91例，环比下降11．68％；去年同期报告43例。无死亡病例报告。     

CDC/AHA Workshop on Markers of Inflammation and Cardiovascular Disease: Application to Clinical and Public Health Practice: ability of inflammatory markers to predict disease in asymptomatic patients: a background paper

There is great interest in moving beyond established risk factors to consider markers of inflammation for the prediction of initial cardiovascular disease events. Inflammatory markers such as leukocyte count, serum amyloid A, C-reactive protein, and vascular outcomes in individuals free of cardiovascular disease at baseline are the key markers that have been investigated in the population setting. A meta-analysis of 11 prospective studies in asymptomatic individuals compared people in the bottom third of the C-reactive protein distribution with those in the top tertile. The authors reported an odds ratio of 2.0 (95% CI 1.6 to 2.5) for coronary heart disease among people in the top tertile. These results are among the strongest assembled thus far to recommend incorporating newer biomarkers into coronary heart disease risk estimation algorithms. A variety of issues should be considered and conditions satisfied before vascular disease risk factors are adopted into regular use. The type of vascular event and the follow-up interval are important features because results for short-, intermediate-, and long-term intervals may yield different results. The factors under consideration should have been standardized, and characteristics such as the variability of the measurements, correlations with established factors, evidence from observational studies and clinical trials, type of effect (linear, nonlinear, dichotomous), improvement in overall prediction (discrimination), generalization of results (calibration), and cost can affect the utility. Each of these issues needs to be considered and the effects on relative, absolute, and population-attributable risks described. In particular, we need to (1) develop sound strategies for implementing new testing and (2) demonstrate the benefit of testing by using the current foundation of prior probabilities developed from already-published risk factor assessments based on large population studies.