Relapsing polychondritis studied by computed tomography

Computed tomographic findings in a patient with relapsing polychondritis are described. Collapse of the cartilage of the nose and calcification in cartilages of the ears were clearly demonstrated. CT scanning was also helpful in evaluating the tracheobronchial tree for airway compromise, which could prove fatal in this condition.     

Ménière's disease: effects of glycerol on tasks involving temporal processing

The present study examined the effect of glycerol ingestion on aspects of auditory performance in subjects having Ménière's disease. It was hypothesized that Ménière's disease may be associated with abnormal firing in the auditory nerve and that this should result in a decreased ability to code the auditory temporal fine structure. Psychoacoustical measures of interaural time discrimination and quasi frequency modulation rate discrimination were used as measures of temporal coding, and performance on these tasks was examined both before and after glycerol ingestion. Pre- and postglycerol measures of speech recognition and audiometric thresholds were also obtained. In agreement with previous results, glycerol-related changes in audiometric thresholds were modest or absent, but improvements in speech recognition were relatively reliable. Improvements in interaural time discrimination and quasi frequency modulation rate discrimination were also observed. The results provide limited support for the hypothesis that Ménière's disease may be associated with a reduced ability to code the temporal fine structure of sound.     

Lung cancer audit in an Irish teaching hospital

Background Lung cancer is the most common cause of cancer-related death in Ireland. There are few complete data sets available as to the stage and cell type of lung cancers at time of presentation in Ireland. Aim To audit the lung cancers presenting to a large Dublin teaching hospital over a 12-month period. Method Prospective evaluation of all lung tumours presenting to our institution over a consecutive 12-month period. Results One hundred and ninety-eight lung cancers presented over the study period. There were 34 cases of small cell carcinoma and 150 cases of non-small cell carcinoma (NSCC). Fourteen patients were too ill or compromised at time of presentation for tissue confirmation. The most common cell type was squamous carcinoma. Eighty-four per cent of the NSCCs were either stage 3 or 4 at presentation. Conclusion Most lung cancers present late in the time course of the disease. Distribution of cell type and location are similar in Ireland and other developed countries.