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991.
EVELINE E O HAGEBEUK RENILDE A S VAN DEN BOSSCHE AL W DE WEERD 《Developmental medicine and child neurology》2013,55(5):480-484
Aim In female children with drug‐resistant seizures and developmental delay from birth, atypical Rett syndrome caused by mutations in the CDKL5 gene should be considered. Several clinical features resemble classic Rett syndrome. Respiratory and sleep abnormalities are frequently present in Rett syndrome, whereas little is known in patients with CDKL5 mutations. Method In four genetically confirmed female patients with CDKL5 mutations (age range 2–15y), the presence of breathing and sleep abnormalities was evaluated using the validated Sleep Disturbance Scale for Children and polysomnography (PSG). Results The Sleep Disturbance Scale for Children indicated disorders of initiating and maintaining sleep, daytime somnolence, and sleep breathing disorders. In one patient, PSG showed central apnoeas during sleep: her total apnoea–hypopnoea index (AHI) was 4.9, of which the central AHI was 3.4/h. When awake, central apnoeas were present in two of the four female children (central AHI 28/h and 41/h respectively), all preceded by hyperventilation. PSG showed low rapid eye movement (REM) sleep (9.7–18.3%), frequent awakenings, and low sleep efficiency (range 59–78%). Interpretation Episodic hyperventilation followed by central apnoeas was present while awake in two of four patients. This may indicate failure of brainstem respiratory centres. In addition, low REM sleep, frequent arousals (not caused by apnoeas/seizures), and low sleep efficiency were present. Similar to Rett syndrome, in patients with CDKL5 mutations PSG seems warranted to evaluate breathing and sleep disturbances. 相似文献
992.
Detection of Herpesvirus,Enterovirus, and Arbovirus infection in patients with suspected central nervous system viral infection in the Western Brazilian Amazon 下载免费PDF全文
993.
A.C.C.O. Maia A.A. Braga G. Soares-Filho V. Pereira A.E. Nardi A.C. Silva 《Brazilian journal of medical and biological research》2014,47(4):265-272
This article is a systematic review of the available literature on the benefits that
cognitive behavioral therapy (CBT) offers patients with implanted cardioverter
defibrillators (ICDs) and confirms its effectiveness. After receiving the device,
some patients fear that it will malfunction, or they remain in a constant state of
tension due to sudden electrical discharges and develop symptoms of anxiety and
depression. A search with the key words “anxiety”, “depression”, “implantable
cardioverter”, “cognitive behavioral therapy” and “psychotherapy” was carried out.
The search was conducted in early January 2013. Sources for the search were ISI Web
of Knowledge, PubMed, and PsycINFO. A total of 224 articles were retrieved: 155 from
PubMed, 69 from ISI Web of Knowledge. Of these, 16 were written in a foreign language
and 47 were duplicates, leaving 161 references for analysis of the abstracts. A total
of 19 articles were eliminated after analysis of the abstracts, 13 were eliminated
after full-text reading, and 11 articles were selected for the review. The collection
of articles for literature review covered studies conducted over a period of 13 years
(1998-2011), and, according to methodological design, there were 1 cross-sectional
study, 1 prospective observational study, 2 clinical trials, 4 case-control studies,
and 3 case studies. The criterion used for selection of the 11 articles was the
effectiveness of the intervention of CBT to decrease anxiety and depression in
patients with ICD, expressed as a ratio. The research indicated that CBT has been
effective in the treatment of ICD patients with depressive and anxiety symptoms.
Research also showed that young women represented a risk group, for which further
study is needed. Because the number of references on this theme was small, further
studies should be carried out. 相似文献
994.
995.
Novaes TF Matos R Gimenez T Braga MM DE Benedetto MS Mendes FM 《International journal of paediatric dentistry / the British Paedodontic Society [and] the International Association of Dentistry for Children》2012,22(6):459-466
International Journal of Paediatric Dentistry 2012; 22: 459-466 Aim. This in vitro study aimed to test the performance of fluorescence-based methods in detecting occlusal caries lesions in primary molars compared to conventional methods. Design. Two examiners assessed 113 sites on 77 occlusal surfaces of primary molars using three fluorescence devices: DIAGNOdent (LF), DIAGNOdent pen (LFpen), and fluorescence camera (VistaProof-FC). Visual inspection (ICDAS) and radiographic methods were also evaluated. One examiner repeated the evaluations after one month. As reference standard method, the lesion depth was determined after sectioning and evaluation in stereomicroscope. The area under the ROC curve (Az), sensitivity, specificity, and accuracy of the methods were calculated at enamel (D1) and dentine caries (D3) lesions thresholds. The intra and interexaminer reproducibility were calculated using the intraclass correlation coefficient (ICC) and kappa statistics. Results. At D1, visual inspection presented higher sensitivities (0.97-0.99) but lower specificities (0.18-0.25). At D3, all the methods demonstrated similar performance (Az values around 0.90). Visual and radiographic methods showed a slightly higher specificity (values higher than 0.96) than the fluorescence based ones (values around 0.88). In general, all methods presented high reproducibility (ICC higher than 0.79). Conclusions. Although fluorescence-based and conventional methods present similar performance in detecting occlusal caries lesions in primary teeth, visual inspection alone seems to be sufficient to be used in clinical practice. 相似文献
996.
Regina C.R.M. Abdulkader Alexandre Braga Libório Denise MAC Malheiros 《Renal failure》2013,35(7):667-673
There are few studies on the relationship between the morphology of acute tubular necrosis (ATN) in native kidneys and late functional recovery. Eighteen patients with acute renal failure (ARF) who had undergone renal biopsy were studied. All had the histological diagnosis of ATN and were followed for at least six months. Clinical characteristics of ARF were analyzed, and histological features were semi-quantitatively evaluated (tubular atrophy, interstitial inflammatory infiltrate, interstitial fibrosis, and ATN). According to the maximal GFR achieved during the follow-up, patients were divided into two groups: complete recovery (GFR ≥ 90 mL/min/1.73 m2) and partial recovery (GFR < 90 mL/min/1.73 m2). Only 39% of the patients achieved complete recovery. Patients with partial recovery achieved their maximal GFR (63 ± 9 mL/min/1.73 m2) 37 ± 14 months after ARF, a period of time similar to those patients with complete recovery (i.e., 54 ± 22 months). Patients with partial recovery had more severe ARF: oliguria was more frequent (90 versus 17%, p < 0.01), and they had higher peak creatinine (13.85 ± 1.12 versus 8.95 ± 1.30 mg/dL, p = 0.01), and longer hospitalization (45 ± 7 versus 20 ± 4 days, p = 0.03). No single histological parameter was associated with partial recovery, but the sum of all was when expressed as an injury index [4.00 (2.73–5.45) versus 2.00 (1.25–3.31), p < 0.05]. In conclusion, among patients with atypical ATN course, those with more severe ARF and tubule-interstitial lesions are more prone to partial recovery. 相似文献
997.
998.
Skare TL Bortoluzzo AB Gonçalves CR Braga da Silva JA Ximenes AC Bértolo MB Ribeiro SL Keiserman M Menin R Carneiro S Azevedo VF Vieira WP Albuquerque EN Bianchi WA Bonfiglioli R Campanholo C Carvalho HM Costa IP Duarte AP Gavi MB Kohem CL Leite NH Lima SA Meirelles ES Pereira IA Pinheiro MM Polito E Resende GG Rocha FA Santiago MB Sauma Mde F Sampaio-Barros PD 《The Journal of rheumatology》2012,39(1):141-147
999.
Sousa O Pereira E Caeiro D Ribeiro J Primo J Braga P Vouga L Gama V 《Revista portuguesa de cardiologia》2012,31(5):395-398
Percutaneous valve replacement for severe aortic stenosis has been shown to be an alternative treatment option for high surgical risk patients. We describe our first valve-in-valve procedure in a patient with a degenerated aortic bioprosthesis and severe regurgitation. 相似文献
1000.
Fontes-Carvalho R Braga P Rodrigues A Bettencourt N Santos L Melica B Rocha J Gon?alves M Ribeiro VG 《Revista portuguesa de cardiologia》2012,31(3):207-214
Thoracic endovascular aortic repair (TEVAR) is a minimally invasive technique which is increasingly used in different thoracic aortic pathologies such as aortic aneurysm, complicated type B aortic dissection, aortic trauma, intramural hematoma and penetrating aortic ulcer. In this paper we discuss the main indications for endovascular stent-grafts in the treatment of thoracic aortic disease, based on three cases in which this procedure was used for three different conditions: degenerative aneurysm, complicated type B dissection and post-traumatic injury. These case reports add to the evidence that TEVAR is a safe and feasible therapeutic alternative in selected patients with thoracic aortic disease, improving aortic remodeling, with relatively low morbidity and mortality. The main complications and difficulties related to the procedure are also discussed. 相似文献