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81.
女性护理专业学生心理健康相关因素分析 总被引:1,自引:0,他引:1
目的:分析护理专业学生心理健康的影响因素。方法:于2005-12-01/15按整群抽样法抽取西安市高校在读的护理专业学生515名作为被调查对象。症状自评量表总分≥187为高分组,总分≤116为低分组。高分组与低分组配比的条件是均为女性,年龄相差不超过3岁。采用症状自评量表、简易应对方式问卷、自尊量表、护理专业学生相关状况调查表进行问卷调查。对调查变量进行单因素和多因素Logistic回归分析。结果:共发放问卷515份,其中2名学生生病未填写调查表,应答率为99.6%。调查中有效问卷共507份,有效率为98.8%。症状自评量表总分高分组与低分组学生各100名。①护理专业学生心理健康相关个人因素(计量变量)单因素分析结果:高分组积极应对、自尊水平得分明显低于低分组(20.47±5.02,22.15±6.02;25.91±3.60,30.96±3.25),差异有显著性意义(P<0.05,P<0.01)。高分组消极应对得分明显高于低分组(12.57±4.08,8.00±4.12),差异有显著性意义(P<0.01)。②护理专业学生心理健康相关个人因素(二分类变量)单因素分析结果表明,高分组与低分组比较差异有显著性的因素有独生子女、远离家人、孤独、学习压力大、担心拿不到学位、自我实现需要的满足、经常被人误会、受人歧视、失恋、有知心朋友、无处倾诉苦恼、睡眠型态紊乱、近1年来本人健康改变、适应新环境、经常参加体育活动、担心毕业分配、现有最担心的事情。③多因素分析显示,学习压力大(OR=10.017)、近1年来本人健康改变(OR=4.384)为护理专业学生心理健康状况不良的独立危险因素,而自我实现需要的满足(OR=0.037)、高水平自尊(OR=0.357)是保护因素。结论:护理专业学生心理健康状况与教育、成长、社会环境等多方面因素相关,其心理健康干预需考虑学生的个人因素有针对性地进行。 相似文献
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84.
Fernando Mallmann Luciano Rosa Márcia Borba Alvaro Della Bona 《The Journal of prosthetic dentistry》2018,119(1):124-131
Statement of problem
The effect of screw-access holes and mechanical cycling on fracture resistance of 3-unit screw-retained zirconia-based implant-supported fixed dental prostheses (ISFDPs) is unknown.Purpose
The purpose of this in vitro study was to evaluate the effect of screw-access holes on the maximum fracture load (Lf) of 3-unit ISFDPs fabricated with the same abutment design for screw (s)-retained and cement (c)-retained with either a metal- or zirconia-based framework, testing the hypotheses that ISFDPs with screw-access holes have the lowest Lf and that mechanical cycling decreases the Lf of screw-retained ISFDPs.Material and methods
Models with fiberglass bases with 2 implants were fabricated. Special abutments were designed to allow for both s- and c-retained ISFDPs. The study considered the type of framework (s-retained metal-based and s-retained zirconia-based), fixation (s and c), and aging (a) with mechanical cycling, resulting in the following experimental groups (n=12): c-retained metal-based ISFDP; s-retained metal-based ISFDP (Ms); s-retained zirconia-based ISFDP aged by mechanical cycling (Zsa); and s-retained metal-based ISFDP aged by mechanical cycling (Msa). All ISFDPs were porcelain veneered and subjected to compressive load to failure. Fracture load data were statistically analyzed using 1-way ANOVA and Tukey range tests (α=.05). Fractography was used to evaluate the fracture surfaces.Results
Cement-retained ISFDP (Zc and Mc) showed the greatest Lf values (P<.001). Zs prostheses showed higher Lf values than those for Ms. Aging significantly decreased the Lf of Zsa but had no effect on Msa. Chipping was the failure mode most frequently found. Only Zs and Zsa ISFDPs showed catastrophic failures.Conclusions
ISFDPs with screw-access holes showed lower Lf values, regardless of the framework type. Mechanical cycling affected the Lf of screw-retained zirconia-based ISFDPs. 相似文献85.
James?C?Barton Howard?W?Wiener Ronald?T?ActonEmail author Rodney?CP?Go 《BMC blood disorders》2005,5(1):5
Background
It has been reported that some persons with hemochromatosis have low total blood lymphocyte counts, but the reason for this is unknown. 相似文献86.
87.
Specificity of autoantibodies in autoimmune thrombocytopenia 总被引:12,自引:5,他引:12
In 42 patients with autoimmune thrombocytopenia (AITP) and a positive direct platelet suspension immunofluorescence test (PSIFT), the antigenic specificity of the autoantibodies was studied. Because the autoantibodies were often not detectable in the serum and additional HLA antibodies may disturb the reaction pattern with the platelet panel, we used eluates prepared from the patients' platelets for this study. Thirty-five patients had antibodies equally reactive with normal platelets, irrespective of their antigenic make-up, but not with the platelets from two Glanzmann's disease patients. Absorption and elution experiments in two patients showed that his was probably not due to the presence of a combination of anti-Zwa and anti-Zwb antibodies. Thus, the majority of autoantibodies against platelets seems to be directed against antigenic determinants not present on Glanzmann's disease platelets, but perhaps located on the platelet-membrane glycoproteins IIb and/or IIIa. In ten patients, antibodies of no, or still unknown, specificity were detected. Three of these had additional antibodies not reactive with the platelets of the two Glanzmann patients. 相似文献
88.
C Pothoulakis U Galili I Castagliuolo CP Kelly S Nikulasson PK Dudeja TA Brasitus JT LaMont 《Gastroenterology》1996,110(6):1704-1712
BACKGROUND & AIMS: Nearly all human sera contain an immunoglobulin G antibody (antigalactose) that binds the trisaccharide Gal alpha 1-3Gal beta 1-4GlcNAc expressed on cells from most mammals but not humans. Because the Clostridium difficile toxin A receptor in rodents contains this trisaccharide, the aim of this study was to examine whether antigalactose could mimic the enterotoxic effects of toxin A and bind to receptors containing this trisaccharide. METHODS: Fluid secretion, [3H]-mannitol permeability, and release of rat mast cell protease II and prostaglandin E2 were measured after luminal exposure of rat colon to either purified human anti-galactose, control immunoglobulin G, toxin A, or buffer. RESULTS: Toxin A (5 micrograms) and antigalactose (250 micrograms) but not control immunoglobulin (250 micrograms) stimulated colonic fluid secretion and caused increased mannitol permeability and rat mast cell protease II release. Antigalactose and toxin A and, to a lesser degree, control immunoglobulin G also stimulated release of prostaglandin E2, but only toxin A produced acute inflammation of rat colonic mucosa. Antigalactose and toxin A bound specifically to a single class of colonic brush border receptors with dissociation constants of 10(-6) mol/L and 5.4 x 10(-8) mol/L, respectively. CONCLUSIONS: Fluid secretion, increased permeability, and mast cell activation occur in rat colon when toxin A or human antigalactose immunoglobulin G bind to receptors bearing the trisaccharide Gal alpha 1-3Gal beta 1-4GlcNAc. (Gastroenterology 1996 Jun;110(6):1704-12) 相似文献
89.
Sanjeev Gupta M.D. M.R.CP. S. H. Saverymuttu M.R.C.P. J. S. R. Gibbs M.R.C.P. D. J. Evans F.R.C. Path. H. J. F. Hodgson D.M. F.R.C.P. 《The American journal of gastroenterology》1985,80(11):877-881
An elderly man with thymoma, myasthenia gravis, and hypogammaglobulinemia developed profuse watery diarrhea. Infusions of gamma-globulin caused the diarrhea to resolve. The patient succumbed to fulminant bronchopneumonia. At necropsy he was found to have widespread cytomegalovirus infection with duodenal and ileal ulceration, subtotal villous atrophy, marked nonspecific inflammation of the small intestine and bronchopneumonia. In addition Herpes simplex infection and invasive candidiasis were present. Patients with immunodeficiency are susceptible to a variety of gastrointestinal pathogens, particularly viral. 相似文献
90.
一氧化氮和一氧化氮合酶与肿瘤放疗敏感性的关系 总被引:1,自引:0,他引:1
一氧化氮(nitricoxide,NO)的生物学作用具有复杂性和多样性,在基础条件下诱导型一氧化氮合酶(induciblenitricoxidesynthase,iNOS)活性很低,当机体遭受微生物内外毒素、炎症介质等刺激时iNOS可诱导合成大量的NO.肿瘤生物学上一般认为高水平的NO对肿瘤细胞具有直接的细胞毒作用,而较低水平的NO具有生长刺激作用.多种试验显示NO的供体能增加肿瘤的放疗敏感性.研究认为,NO的生物学作用可能是通过p53依赖途径介导的.调节NO杀灭肿瘤或促进肿瘤生长,p53起到关键性的作用.已有多种药品作为放射敏化剂,NO供体药物在体内给药可能导致系统低血压,增加肿瘤血液灌注和氧合作用,具有潜在的促进肿瘤生长的作用,限制了其临床使用.直接将iNOS基因转染入肿瘤细胞内,肿瘤内的乏氧环境,可降低iNOS的活性而影响NO的产量.携带iNOS基因的腺病毒(adenoviralvectorcarryingtheiNOScDNA,AdiNOS)转染靶细胞导致iNOS过表达,产生大量NO,有望成为一种增加肿瘤放疗敏感性有效可行的方法. 相似文献