Epidemiological observations on the physical activities of patients with arterial hypertension

The authors point out the results of some multidisciplinary epidemiological researches concerning the relation between the multifactorial etiology of arterial hypertension (AHT) in employers working in two factories and the nature of physical activity. The results show that the highest percentage of AHT cases is in the persons which do not have physical activity (occupational, housing or leisure). The women with AHT, which are frequently supra-ponderously, make a low level of physical activity. They have effort respiratory modifications in 40% of cases. The decreasing interest for control and prevention of health risks of the level of occupational health services has medical and social negative effects on long term.     

A multi-center prospective cohort study of benign breast disease and risk of subsequent breast cancer

Objective  

We used a nested case–control design within a large, multi-center cohort of women who underwent a biopsy for benign breast disease (BBD) to assess the association of broad histologic groupings and specific histologic entities with risk of breast cancer.     

Phase I trial of infusional cyclophosphamide, doxorubicin, and etoposide plus granulocyte-macrophage colony stimulating factor (GM-CSF) in non-hodgkin’s lymphoma

PURPOSE: To determine the recommended phase II dose (RPTD) of a 96-h continuous intravenous infusion (CIVI) of cyclophosphamide (200, 300, or 400 mg/m2/d) and etoposide (60 or 90 mg/m2/d) when used in conjunction with doxorubicin (12.5 mg/m2/d) (CDE) given every 28 d plus granulocyte-macrophage colony stimulating factor (GM-CSF) in patients with poor prognosis non-Hodgkin's lymphoma (Group A), and the same regimen given every 21 d (Group B). METHODS: In Group A, infusional CDE was repeated every 28 d, GM-CSF (250 microg/m2) was given subcutaneously from d 6 until neutrophil recovery, with dose escalation in cohorts of three to six evaluable patients. The RPTD of cyclophosphamide and etoposide established in Group A was then used with CDE given every 3 wk (Group B) with GM-CSF given on d 6-20, and dose escalation was attempted again. RESULTS: In Group A, the RPTD of cyclophosphamide and etoposide were 300 mg/m2/d and 90 mg/m2/d, respectively; prolonged neutropenia was the dose-limiting toxicity. In Group B, use of GM-CSF on d 6-20 did not facilitate dose escalation above the RPTD established in Group A. Complete response occurred in 13/26 patients (50%) with no prior chemotherapy, and in 4/16 patients (25%) who had relapsed after prior chemotherapy. CONCLUSIONS: Because of the increase in dose and dose-density afforded by the administration of GM-CSF, the relative dose intensity was increased by twofold for cyclophosphamide (400 vs 200 mg/m2/wk) and etoposide (120 vs 60 mg/m2/wk), and by 1.3-fold for doxorubicin (16.7 vs 12.5 mg/m2/wk).     

Alcohol intake assessment in a group of hypertensive adults

The assessment was realised in order to obtain data for a local intervention program for preventing primary hypertension in young adults through an education program. 269 persons, of both sexes, were investigated. The frequency of elevated blood pressure values is 11.2% and the prevalence of arterial hypertension is 8.73%. The frequency of alcohol consumers is different according to gender (18.6% for male and 3.4% for female).     

伤科洗方的实验研究

为了验证伤科洗方的最佳熏洗组合 ,改进伤科洗方剂型 ,探讨伤科洗方治疗SD大鼠软组织损伤的部分作用机理 ,将 6 0只只SD大白鼠随机均分为 6组 ,其中 4个试验组 (A组 :熏洗时间 30分 酒 浓缩剂。B组 :熏洗时间 30分 醋 散剂。C组 :熏洗时间 6 0分 醋 散剂。D组 :熏洗时间 6 0分 酒 浓缩剂 )和 1个空白对照组 (E组 0 .9%生理盐水 )及 1个最佳熏洗组合组(F组 )。试验组采用 3因素 2水平正交设计 ,制做成软组织损伤动物模型 ,分别进行熏洗治疗 ,每天 1次 ,7天为 1个疗程 ,治疗后分别观察症状和体征、组织病理学变化 ,6 酮 前列腺素F1a和血栓素B2的变化。结果显示 ,最佳熏洗组合为熏洗时间 6 0分 酒 浓缩剂 (F组 ) ,浓缩剂优于散剂。从而为临床应用提供了依据。     

The Impact of Implementing a Comprehensive Surgical Program on the Surgical Cohort at a Remote Referral Hospital in Southeastern Liberia

World Journal of Surgery - Liberia has an extreme health workforce shortage, particularly with respect to surgery. JJ Dossen Memorial (JJD) is a public referral hospital supported by Partners in...     

我国医疗机构分娩镇痛现状调查研究

目的了解我国医疗机构分娩镇痛现状,为今后助产士培训及相关政策制定提供参考。方法采用横断面调查法对22个省/直辖市/自治区的1 256所医疗机构分娩镇痛现状进行调查。结果 1 256所医疗机构,具备药物镇痛技术976所(77.7%),具备非药物镇痛技术1 243所(99.0%)。非药物镇痛措施以心理支持(1 092所,82.8%),自由体位(907所,73.0%),拉玛泽呼吸法(887所,71.4%)为主。三级医院具备药物镇痛及非药物镇痛技术的比例显著高于二级医院;妇幼保健医院及专科医院具备药物镇痛技术的比例显著高于综合医院(均P0.017);医疗机构中主张硬膜外麻醉者主要为产科医生(653所,68.2%),其次是产妇(579所,60.4%)、麻醉科医生(518所,54.1%)、家属(445所,46.5%)、助产士(436所,45.5%)。我国医疗机构未开展非药物镇痛措施的主要原因是人力资源不足(239所,69.5%)以及助产士未经培训(190所,55.2%)。结论我国医疗机构对非药物分娩镇痛的作用未足够重视,人力资源不足以及助产士未经相关培训阻碍了非药物镇痛措施的普及和开展,应采取措施针对阻碍因素进行干预以推动非药物镇痛措施的开展。     

妇产科护士睡眠质量与心理健康状况调查

[目的]探讨妇产科护士睡眠质量与心理健康之间的关系。[方法]采用匹兹堡睡眠质量调查表、症状自评量表(SCL-90)对我院88名妇产科护士进行调查。[结果]88名妇产科护士中15人睡眠质量较差;对SCL-90因子分析发现,妇产科护士躯体化、强迫2个因子平均分显著高于国内常模(P<0.05);相关分析表明:匹兹堡睡眠质量评分与SCL-90各因子分及其总均分除睡眠药物外皆呈显著的正相关,睡眠质量差的护士SCL-90各因子平均分高于睡眠质量好的护士。[结论]妇产科护士睡眠质量与心理健康状况密切相关,应引起有关领导的关注。