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141.
Acute flank pain: comparison of non-contrast-enhanced CT and intravenous urography 总被引:26,自引:2,他引:24
Smith RC; Rosenfield AT; Choe KA; Essenmacher KR; Verga M; Glickman MG; Lange RC 《Radiology》1995,194(3):789
142.
Hunter DW; Castaneda-Zuniga WR; Coleman CC; Young AT; Salomonowitz E; Mercado S; Amplatz K 《Radiology》1984,152(3):631-635
A total of 31 patients with 45 episodes of failing arteriovenous dialysis fistulas was studied. Fistula failure was usually due to venous and/or anastomotic stenosis, often in conjunction with thrombosis. Abnormalities were treated by percutaneous dilation and occasionally streptokinase infusion. Most complications and failures occurred either in patients with recently created fistulas or in those with multiple or long segment stenosis associated with thrombosis. Patients with a single nonobstructing stenosis were very successfully treated with percutaneous techniques, which are the treatment of choice for this condition. 相似文献
143.
In alcoholic liver disease (fatty infiltration, alcoholic cirrhosis), the liver is diffusely abnormal on ultrasound. Changes in size, dilatation of the hepatic veins, and ascites may also occur. The authors conducted a histological correlation of these abnormalities in 22 alcoholic patients and 16 controls, grading the changes on a scale of 0 to 4+ for fat, fibrosis, and necrosis and noting tumor whenever present. Ultrasound detected abnormality in 21 cases (sensitivity = 95%) and correctly identified 15 controls (specificity = 94%). Of the 5 tumors seen, 4 hepatomas were detected and biopsied and 1 metastatic squamous-cell carcinoma was missed. Applications of commercially available A-scan module are considered and its limitations discussed. With the exception of minimal change (1+ fat or fibrosis), ultrasound detected many of the pathological changes seen in alcoholic liver disease. 相似文献
144.
Georgi Atanasov MD Hans‐Michael Hau MD Corinna Dietel PhD Christian Benzing MD Felix Krenzien MD Andreas Brandl MD Julianna P. Englisch Georg Wiltberger MD Katrin Schierle MD Simon C. Robson MD PhD Anja Reutzel‐Selke PhD Sven Jonas MD PhD Andreas Pascher MD PhD Johann Pratschke MD PhD Moritz Schmelzle MD PD 《Journal of surgical oncology》2016,114(1):91-98
145.
AT Kalghatgi AK Praharaj AK Sahni D Pradhan S Kumaravelu PL Prasad A Nagendra 《Medical Journal Armed Forces India》2008
Background: Polymerase chain reaction (PCR) is useful for rapid microbial detection in body fluids with low microbial load. It is easier to use universal or broad range primers for the amplification of conserved stretches of DNA common to all bacteria like 16S rRNA gene, followed by restriction fragment length polymorphism (RFLP) of PCR products. 相似文献
146.
147.
Longitudinal Changes in BMD and Fracture Risk in Orthotopic Liver Transplant Recipients Not Using Bone‐Modifying Treatment
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Charlotte G Krol Olaf M Dekkers Herman M Kroon Ton J Rabelink Neveen AT Hamdy 《Journal of bone and mineral research》2014,29(8):1763-1769
Osteoporosis is prevalent in end‐stage liver disease, but data on long‐term changes in bone mineral density (BMD) and related fracture incidence after orthotopic liver transplantation (OLT) are scarce. We evaluated BMD changes up to 5 years in consecutive recipients of a successful OLT at the Leiden University Medical Centre between 2000 and 2011, in whom sequential BMD data were available. Spinal radiographs were available at time of screening and at 6 and 12 months post‐OLT and were assessed for vertebral fractures by two independent observers using Genant's semiquantitative method. Patients were excluded from the study when started on bisphosphonates. A total of 201 patients (71% men), median age 53 years (range, 18–70 years) were included in the study. Most common liver pathology was viral (27%) or alcoholic liver disease (25%). All patients received prednisone for at least 6 months after transplantation and the majority received either tacrolimus or cyclosporine for immunosuppression. At time of screening for OLT, osteoporosis and osteopenia were found in 18% and 36% of patients at the lumbar spine (LS), respectively, and in 9% and 42% at the femoral neck (FN), respectively. T‐scores declined significantly at both sites 6 months after OLT, but increased thereafter at the LS, reaching pretransplantation values at 2 years and remaining stable thereafter. FN T‐scores remained consistently lower than pretransplantation values. The prevalence of vertebral fractures increased from 56% at screening to 71% at 1 year after OLT, with a fracture incidence of 34%. BMD changes did not predict fracture risk. Osteoporosis, osteopenia, and vertebral fractures are prevalent in patients with end‐stage liver disease. An overall decline in BMD is observed within the first 6 months after OLT, with subsequent recovery to pretransplantation values at the LS, but not at the FN. Vertebral fracture risk is high after OLT regardless of changes in BMD. © 2014 American Society for Bone and Mineral Research. 相似文献
148.
149.
Christian Benzing Hans-Michael Hau Georgi Atanasov Johannes Broschewitz Felix Krenzien Michael Bartels 《Acta chirurgica Belgica》2016,116(6):340-345
Background: Combined resections of the liver and pancreas are related to high complication and mortality rates. The present study assessed the outcome of these procedures and identified specific risk factors for morbidity and mortality.Methods: Between January 2001 and April 2012, 28 combined liver/pancreas resections were performed at our institution. All patients were retrospectively analysed using a database with regards to baseline characteristics, surgical procedures, complications and survival.Results: Among the pancreatic resections, there were 12 (42.9%) Kausch–Whipple (KW), 9 (32.1%) pylorus-preserving pancreaticoduodenectomy (PPPD), 6 (21.4%) distal pancreatectomies (DP) and 1 (3.6%) total pancreaticoduodenectomy (TPD). In 12 (48.9%) cases, major complications (grade IIIb–V) were observed. Overall survival was 35 months (SD?=?40.5) and the 3-year survival rate was 35.7% (1-year survival rate: 50%).Discussion: Combined resections of the liver and pancreas are associated with high complication rates, especially if major liver resections are performed. Therefore, it is mandatory to do a thorough evaluation of potential patients. 相似文献
150.
Katharina Viola Sabine Kopf Lucie Rarova Kanokwan Jarukamjorn Nicole Kretschy Mathias Teichmann Caroline Vonach Atanas G. Atanasov Benedikt Giessrigl Nicole Huttary Ingrid Raab Sigurd Krieger Miroslav Strnad Rainer de Martin Philipp Saiko Thomas Szekeres Siegfried Knasmüller Verena M. Dirsch Walter Jäger Michael Grusch Helmut Dolznig Wolfgang Mikulits Georg Krupitza 《Archives of toxicology》2013,87(7):1301-1312
Health beneficial effects of xanthohumol have been reported, and basic research provided evidence for anti-cancer effects. Furthermore, xanthohumol was shown to inhibit the migration of endothelial cells. Therefore, this study investigated the anti-metastatic potential of xanthohumol. MCF-7 breast cancer spheroids which are placed on lymphendothelial cells (LECs) induce “circular chemorepellent-induced defects” (CCIDs) in the LEC monolayer resembling gates for intravasating tumour bulks at an early step of lymph node colonisation. NF-κB reporter-, EROD-, SELE-, 12(S)-HETE- and adhesion assays were performed to investigate the anti-metastatic properties of xanthohumol. Western blot analyses were used to elucidate the mechanisms inhibiting CCID formation. Xanthohumol inhibited the activity of CYP, SELE and NF-kB and consequently, the formation of CCIDs at low micromolar concentrations. More specifically, xanthohumol affected ICAM-1 expression and adherence of MCF-7 cells to LECs, which is a prerequisite for CCID formation. Furthermore, markers of epithelial-to-mesenchymal transition (EMT) and of cell mobility such as paxillin, MCL2 and S100A4 were suppressed by xanthohumol. Xanthohumol attenuated tumour cell-mediated defects at the lymphendothelial barrier and inhibited EMT-like effects thereby providing a mechanistic explanation for the anti-intravasative/anti-metastatic properties of xanthohumol. 相似文献