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101.
Mohammad Hossein Gharache Seyed Yousef Paighambary Amin Golpour 《Comparative clinical pathology》2014,23(4):979-982
The aim of current research was to determine hematological and biochemical parameters of captured kutum with gill net and beach seine. A total of 16 matured kutums were used for blood sampling from each device. The result showed significant differences in white blood cells, red blood cell, mean corpuscle volume, Ca2+, Cl?, and cholesterol between gill net and beach seine methods, but there were no significant differences in other parameters. Based on obtained results during our experiment, we concluded that the stress due to capture can influence the blood parameters, and different capture methods lead to different reactions in blood parameters. 相似文献
102.
103.
Frank Wegmann Amin E. Moghaddam Torben Schiffner Kate H. Gartlan Timothy J. Powell Rebecca A. Russell Matthijs Baart Emily W. Carrow Quentin J. Sattentau 《Clinical and Vaccine Immunology : CVI》2015,22(9):1004-1012
The continued discovery and development of adjuvants for vaccine formulation are important to safely increase potency and/or reduce the antigen doses of existing vaccines and tailor the adaptive immune response to newly developed vaccines. Adjuplex is a novel adjuvant platform based on a purified lecithin and carbomer homopolymer. Here, we analyzed the adjuvant activity of Adjuplex in mice for the soluble hemagglutinin (HA) glycoprotein of influenza A virus. The titration of Adjuplex revealed an optimal dose of 1% for immunogenicity, eliciting high titers of HA-specific IgG but inducing no significant weight loss. At this dose, Adjuplex completely protected mice from an otherwise lethal influenza virus challenge and was at least as effective as the adjuvants monophosphoryl lipid A (MPL) and alum in preventing disease. Adjuplex elicited balanced Th1-/Th2-type immune responses with accompanying cytokines and triggered antigen-specific CD8+ T-cell proliferation. The use of the peritoneal inflammation model revealed that Adjuplex recruited dendritic cells (DCs), monocytes, and neutrophils in the context of innate cytokine and chemokine secretion. Adjuplex neither triggered classical maturation of DCs nor activated a pathogen recognition receptor (PRR)-expressing NF-κB reporter cell line, suggesting a mechanism of action different from that reported for classical pathogen-associated molecular pattern (PAMP)-activated innate immunity. Taken together, these data reveal Adjuplex to be a potent and well-tolerated adjuvant with application for subunit vaccines. 相似文献
104.
Laila E. Amin Marmar Montaser 《Australian endodontic journal : the journal of the Australian Society of Endodontology Inc》2021,47(1):11-19
The response of the dentin–pulp complex in rat teeth was investigated after direct capping with biodentine with or without bone marrow‐derived stem cells (BMDSCs). Following mechanical exposure, pulps were randomly capped with one of the followings materials: calcium hydroxide, biodentine or 1 × 105 BMDSCs mL?1 + biodentine. Histological examination was performed by light microscopy after 1, 3 and 5 weeks. Inflammatory reaction, necrotic tissue formation and calcific bridge formation were scored. Analysis showed that compared with the effects of calcium hydroxide or biodentine, BMDSCs + biodentine substantially reduced inflammatory reaction and necrotic tissue while promoting calcified tissue formation. Therefore, the combination of biodentine and BMDSCs could potentially stimulate pulp tissue regeneration after direct pulp capping. 相似文献
105.
Mohammad Hossein Baradaranfar Zeynab Sadat Ahmadi Mohammad Hossein Dadgarnia Mohammad Hossein Bemanian Saeid Atighechi Ghasem Karimi Abolhasan Halvani Nasim Behniafard Amin Baradaranfar Tohid Emami Meybodi 《European archives of oto-rhino-laryngology》2014,271(2):311-316
Chronic rhinosinusitis is a common inflammatory condition in western countries. Nasal polyposis has different symptoms such as nasal obstruction, anterior or posterior nasal drip, reduced sense of smell, and facial pain. Medical and endoscopic treatments are the two main treatments for nasal polyposis. Our aim was to compare the efficacy of different methods on olfactory function. This is a non-randomized clinical trial study that was done on 60 patients who were divided into two groups (medical and surgical). Patients were matched based on age, history of smoking, and the severity of obstruction. The radiologist score of Lund-Mackay staging system was used to match patients in two arms of the trial based on the severity of nasal obstruction. Patients in surgery groups underwent functional endoscopic sinus surgery under general anesthesia and then received Fluticasone propionate nasal spray for 8 weeks (400 mcg bd). Patients in the medical group were only prescribed with Fluticasone propionate with the same duration and same dose as mentioned. As a result of treatment protocol, both medical and surgical group experienced improvement in olfactory function but statistical analyses revealed that surgery resulted in better resolution of symptoms. Our observation revealed that combined treatment had a better effect than medical treatment in restoring olfaction in patients with nasal polyposis. 相似文献
106.
107.
Hassan AS Sakwa EM Nabwera HM Taegtmeyer MM Kimutai RM Sanders EJ Awuondo KK Mutinda MN Molyneux CS Berkley JA 《AIDS and behavior》2012,16(1):5-12
A cohort design was used to determine uptake and drop out of 213 HIV-exposed infants eligible for Early Infant Diagnosis (EID)
of HIV. To explore service providers and care givers knowledge, attitudes and perceptions of the EID process, observations
and in-depth interviews were conducted. 145 (68%) infants enrolled after 2 months of age. 139 (65%) dropped out before follow
up to 18 months old. 60 (43%) drop outs occurred within 2 months of enrolment. Maternal factors associated with infant drop
out were maternal loss to follow up (48 [68%] vs. 8 [20%], P < 0.001) and younger maternal age (27.2 vs. 30.1 years, P = 0.033). Service providers and caregivers had inadequate training, knowledge and understanding of EID. Poverty and lack
of social support were challenges in accessing EID services. EID should be more closely aligned within PMTCT services, integrated
with routine mother and child health (MCH) activities and its implementation more closely monitored. 相似文献
108.
D.A. Parry R.S. Oeppen M.S.A. Amin P.A. Brennan 《The British journal of oral & maxillofacial surgery》2018,56(5):367-370
Workplace-related illness is common in the UK, and in healthcare more than five million working days over 10 years have been lost as a result. Occupational stress is well known and can affect clinicians at any stage, yet many healthcare professionals continue to work with this or other psychological problems (including anxiety, chronic fatigue, and burnout) as they do not wish to let their colleagues down. Mental health issues might be dismissed, particularly in surgery, because there is a misconception that surgeons can cope better with stress than those working in other specialties, and are better protected from clinical burnout. The benefit of exercise on physical health is clear, but its role in the maintenance of good mental health and well-being should not be underestimated. As society adopts an increasingly sedentary lifestyle, exercise for many has a lower priority than other activities. In this article we give an overview of the mental health issues that might affect doctors and surgeons, and explore how exercise can benefit our well-being and clinical performance. 相似文献
109.
A brief commentary on ‘Response letter to “What should be taken into account during study on immunoregulatory effects of helminths: a critical analyzing on downregulation of immune responses in asthmatic patients by ES products of Marshallagia marshalli”’
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Amin Zakeri 《The clinical respiratory journal》2018,12(4):1763-1764
110.
Cellular expression of CD markers in immune thrombocytopenic purpura: implications for prognosis
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Masumeh Maleki Behzad Ali Amin Asnafi Mohammad Ali Jalalifar Mostafa Moghtadaei Kaveh Jaseb Najmaldin Saki 《APMIS : acta pathologica, microbiologica, et immunologica Scandinavica》2018,126(6):523-532
Immune thrombocytopenic purpura (ITP) is an autoimmune bleeding disorder associated with platelet destruction. Abnormalities in frequency and function of different immune cells can play a crucial role in this disease. The aim of this study was to evaluate the prognostic value of CD markers’ expressions by immune cells in ITP. Peripheral blood samples were collected from 25 ITP patients before and after treatment. The expression of CD markers was evaluated by flow cytometry technique. The expression of CD38 and CD56 was significantly lower before treatment than after it (p = 0.025 and p = 0.036, respectively). Furthermore, a positive correlation was found between CD38 expression with platelet count before (r = 0.496, p = 0.012) and after treatment (r = 0.404, p = 0.045). No significant relationship was found between this marker and platelet count while CD4 expression was higher before treatment than after it (p = 0.002). In conclusion, CD38 may have independent prognostic value in ITP and we suggest that it can be a prognostic marker for this disease. 相似文献