全文获取类型
收费全文 | 4246篇 |
免费 | 349篇 |
国内免费 | 12篇 |
专业分类
耳鼻咽喉 | 67篇 |
儿科学 | 137篇 |
妇产科学 | 84篇 |
基础医学 | 606篇 |
口腔科学 | 58篇 |
临床医学 | 492篇 |
内科学 | 819篇 |
皮肤病学 | 77篇 |
神经病学 | 548篇 |
特种医学 | 167篇 |
外科学 | 574篇 |
综合类 | 13篇 |
预防医学 | 470篇 |
眼科学 | 29篇 |
药学 | 250篇 |
中国医学 | 12篇 |
肿瘤学 | 204篇 |
出版年
2024年 | 5篇 |
2023年 | 73篇 |
2022年 | 77篇 |
2021年 | 229篇 |
2020年 | 129篇 |
2019年 | 163篇 |
2018年 | 240篇 |
2017年 | 161篇 |
2016年 | 164篇 |
2015年 | 179篇 |
2014年 | 227篇 |
2013年 | 264篇 |
2012年 | 415篇 |
2011年 | 378篇 |
2010年 | 182篇 |
2009年 | 163篇 |
2008年 | 255篇 |
2007年 | 215篇 |
2006年 | 230篇 |
2005年 | 205篇 |
2004年 | 141篇 |
2003年 | 143篇 |
2002年 | 103篇 |
2001年 | 13篇 |
2000年 | 13篇 |
1999年 | 20篇 |
1998年 | 10篇 |
1997年 | 7篇 |
1996年 | 17篇 |
1995年 | 9篇 |
1994年 | 8篇 |
1993年 | 8篇 |
1992年 | 4篇 |
1990年 | 4篇 |
1985年 | 4篇 |
1983年 | 4篇 |
1981年 | 5篇 |
1976年 | 4篇 |
1942年 | 5篇 |
1932年 | 3篇 |
1928年 | 5篇 |
1926年 | 7篇 |
1923年 | 8篇 |
1922年 | 6篇 |
1921年 | 5篇 |
1913年 | 3篇 |
1912年 | 6篇 |
1911年 | 7篇 |
1910年 | 3篇 |
1874年 | 3篇 |
排序方式: 共有4607条查询结果,搜索用时 672 毫秒
921.
Alexis Sentís Irina Kislaya Nathalie Nicolay Hinta Meijerink Jostein Starrfelt Ivn Martínez-Baz Jesús Castilla Katrine Finderup Nielsen Christian Holm Hansen Hanne-Dorthe Emborg Anthony Nardone Tarik Derrough Marta Valenciano Baltazar Nunes Susana Monge the VEBIS-Lot working group VEBIS-Lot working group Ausenda Machado Carlos Dias Itziar Casado Cristina Burgui Amparo Larrauri Clara Mazagatos 《Euro surveillance : bulletin européen sur les maladies transmissibles = European communicable disease bulletin》2022,27(30)
By employing a common protocol and data from electronic health registries in Denmark, Navarre (Spain), Norway and Portugal, we estimated vaccine effectiveness (VE) against hospitalisation due to COVID-19 in individuals aged ≥ 65 years old, without previous documented infection, between October 2021 and March 2022. VE was higher in 65–79-year-olds compared with ≥ 80-year-olds and in those who received a booster compared with those who were primary vaccinated. VE remained high (ca 80%) between ≥ 12 and < 24 weeks after the first booster administration, and after Omicron became dominant. 相似文献
922.
Nicole Frumento Alexis Figueroa Tingchang Wang Muhammad N. Zahid Shuyi Wang Guido Massaccesi Georgia Stavrakis James E. Crowe Jr Andrew I. Flyak Hongkai Ji Stuart C. Ray George M. Shaw Andrea L. Cox Justin R. Bailey 《The Journal of clinical investigation》2022,132(15)
A prophylactic hepatitis C virus (HCV) vaccine that elicits neutralizing antibodies could be key to HCV eradication. However, the genetic and antigenic properties of HCV envelope (E1E2) proteins capable of inducing anti-HCV broadly neutralizing antibodies (bNAbs) in humans have not been defined. Here, we investigated the development of bNAbs in longitudinal plasma of HCV-infected persons with persistent infection or spontaneous clearance of multiple reinfections. By measuring plasma antibody neutralization of a heterologous virus panel, we found that the breadth and potency of the antibody response increased upon exposure to multiple genetically distinct infections and with longer duration of viremia. Greater genetic divergence between infecting strains was not associated with enhanced neutralizing breadth. Rather, repeated exposure to antigenically related, antibody-sensitive E1E2s was associated with potent bNAb induction. These data reveal that a prime-boost vaccine strategy with genetically distinct, antibody-sensitive viruses is a promising approach to inducing potent bNAbs in humans. 相似文献
923.
Thrombopoietin Receptor Agonist Use in Children: Data From the Pediatric ITP Consortium of North America ICON2 Study
下载免费PDF全文
![点击此处可从《Pediatric blood & cancer》网站下载免费的PDF全文](/ch/ext_images/free.gif)
Cindy Neunert MD MSCS Jenny Despotovic DO MS Kristina Haley DO MCR Michele P. Lambert MD Kerri Nottage MD Kristin Shimano MD Carolyn Bennett MD Robert Klaassen MD FRCP Kimo Stine MD Alexis Thompson MD Yves Pastore MD Travis Brown BS Peter W. Forbes MA Rachael F. Grace MD MMSc 《Pediatric blood & cancer》2016,63(8):1407-1413
924.
925.
926.
Neurofibromatosis type 1 is a relatively common genetic disorder with variable phenotypes. Tumors with features of both glomus tumors and neurofibromas are exceedingly rare in literature. Herein, we report a not yet described neoplasm with features of both a glomangioma/glomus tumor and a neurofibroma arising in a patient with segmental neurofibromatosis. Our case report supports the theory of a common lineage/ancestor cell between neurofibromas and glomus tumors and adds it to the spectrum of neoplasms that may arise in the setting of Von Recklinghausen's disease. 相似文献
927.
The holographic weight of evidence model (van der Helm & Leeuwenberg, J Math Psychol, 35, 1991, 151; van der Helm & Leeuwenberg, Psychol Rev, 103, 1996, 429) estimates that the perceptual goodness of moiré structures (Glass patterns), irrespective of their global form, is comparable to that of reflection symmetry. However, both behavioural and neuroscience evidences suggest that certain Glass forms (i.e. circular and radial structures) are perceptually more salient than others (i.e. translation structures) and may recruit different perceptual mechanisms. In this study, we tested whether brain responses for circular, radial and translation Glass patterns are comparable to the response for onefold bilateral reflection symmetry. We recorded an event‐related potential (ERP), called the sustained posterior negativity (SPN), which has been shown to index perceptual goodness of a range of regularities. We found that circular and radial Glass patterns generated a comparable SPN amplitude to onefold reflection symmetry (in line with the prediction of the holographic model), starting approx. 180 ms after stimulus onset. Conversely, the SPN response to translation Glass patterns had a longer latency (approx. 400 ms). These results show that Glass patterns are a special case of visual regularity, and perceptual goodness may not be fully explained by the holographic identities that constitute it. Specialised processing mechanisms might exist in the regularity‐sensitive extrastriate areas, which are tuned to global form configurations. 相似文献
928.
929.
Tiziana Granata Francesca Bisulli Alexis Arzimanoglou Rodrigo Rocamora 《Epileptic Disord》2020,22(4):439-442
Aims. The COVID‐19 pandemic shook European healthcare systems, with unavoidable gaps in the management of patients with chronic diseases. We describe the impact of the pandemic on epilepsy care in three tertiary epilepsy centres from Spain and Italy, the most affected European countries. Methods. The three epilepsy centres, members of the European EpiCARE network, manage more than 5,700 people with epilepsy. In Bologna and Barcelona, the hospitals housing the epilepsy centres were fully converted into COVID‐19 units. We describe the reorganization of the clinics and report on the frequency of SARS‐CoV‐2 in people with epilepsy as well as the frequency of seizures in patients admitted to the COVID units. Finally, we elaborate on critical issues regarding the second phase of the pandemic. Results. The activities related to epilepsy care were reduced to less than 10% and were deprioritized. Discharges were expedited and elective epilepsy surgeries, including vagal nerve stimulator implantations, cancelled. Hospitalizations and EEG examinations were limited to emergencies. The outpatient visits for new patients were postponed, and follow‐up visits mostly managed by telehealth. Antiseizure medication weaning plans and changes in vagal nerve stimulator settings were halted. Among the 5,700 people with epilepsy managed in our centres, only 14 tested positive for SARS‐CoV‐2, without obvious impact on their epilepsy. None of the 2,122 patients admitted to COVID units experienced seizures among the early symptoms. Conclusion. Epilepsy care was negatively impacted by the pandemic, irrespective of COVID‐19 epidemiology or conversion of the hospital into a COVID‐19 centre. The pandemic did not silence the needs of people with epilepsy, and this must be considered in the planning of the second phase. 相似文献