全文获取类型
收费全文 | 195016篇 |
免费 | 9449篇 |
国内免费 | 512篇 |
专业分类
耳鼻咽喉 | 2892篇 |
儿科学 | 6150篇 |
妇产科学 | 4806篇 |
基础医学 | 26895篇 |
口腔科学 | 6500篇 |
临床医学 | 12833篇 |
内科学 | 46843篇 |
皮肤病学 | 6403篇 |
神经病学 | 15939篇 |
特种医学 | 4585篇 |
外国民族医学 | 30篇 |
外科学 | 24508篇 |
综合类 | 1055篇 |
一般理论 | 49篇 |
预防医学 | 18587篇 |
眼科学 | 3961篇 |
药学 | 13441篇 |
中国医学 | 840篇 |
肿瘤学 | 8660篇 |
出版年
2023年 | 1079篇 |
2022年 | 1413篇 |
2021年 | 4414篇 |
2020年 | 2311篇 |
2019年 | 4427篇 |
2018年 | 6363篇 |
2017年 | 3933篇 |
2016年 | 3861篇 |
2015年 | 4185篇 |
2014年 | 5515篇 |
2013年 | 8015篇 |
2012年 | 12792篇 |
2011年 | 13449篇 |
2010年 | 7143篇 |
2009年 | 5853篇 |
2008年 | 10982篇 |
2007年 | 11592篇 |
2006年 | 10966篇 |
2005年 | 10893篇 |
2004年 | 9796篇 |
2003年 | 9290篇 |
2002年 | 8793篇 |
2001年 | 5979篇 |
2000年 | 6519篇 |
1999年 | 5172篇 |
1998年 | 1302篇 |
1997年 | 952篇 |
1996年 | 863篇 |
1995年 | 740篇 |
1994年 | 597篇 |
1993年 | 565篇 |
1992年 | 2285篇 |
1991年 | 2091篇 |
1990年 | 1880篇 |
1989年 | 1624篇 |
1988年 | 1444篇 |
1987年 | 1391篇 |
1986年 | 1319篇 |
1985年 | 1190篇 |
1984年 | 884篇 |
1983年 | 749篇 |
1979年 | 787篇 |
1975年 | 599篇 |
1974年 | 676篇 |
1973年 | 728篇 |
1972年 | 627篇 |
1971年 | 627篇 |
1970年 | 607篇 |
1969年 | 598篇 |
1968年 | 538篇 |
排序方式: 共有10000条查询结果,搜索用时 31 毫秒
41.
Maria Gonzalez-Cao Cristina Carrera Juan Francisco Rodriguez Moreno Pedro Rodríguez-Jiménez Mónica Antoñanzas Basa Rosa Feltes Ochoa Teresa Puertolas Eva Muñoz-Couselo José Luis Manzano Ivan Marquez-Rodas Juan Martín-Liberal Ainara Soria Pilar Lopez Criado Almudena Garcia-Castaño Aram Boada Pablo Ayala de Miguel Susana Puig Guillermo Crespo Alfonso Berrocal 《Journal of the American Academy of Dermatology》2021,84(5):1412-1415
42.
目的 收集藿香正气汤的主要活性成分,通过分子对接及网络药理学探讨其防控新型冠状病毒肺炎(COVID-19)的有效成分及治疗机制。方法 通过基于配体-蛋白质相互作用的计算方法,以瑞德西韦为对照,探索藿香正气汤潜在治疗COVID-19的成分,并选出对接较好成分进行药理学机制预测,初探其药理学机制。结果 本研究筛选出5种与新冠病毒3CLpro结合能力强于瑞德西韦的小分子成分。网络药理学初步预测抗病毒途径可能是通过PI3K-Akt 信号通路影响病毒复制。结论 成分C1-C5与3CLpro结合良好,推测其可能是潜在的3CLpro的抑制剂,为抗病毒天然药物的开发提供了理论依据。 相似文献
43.
44.
José Antonio Pereira Miguel Pera Manuel López-Cano Marta Pascual Sandra Alonso Silvia Salvans Marta Jiménez-Toscano Alba González-Martín Luis Grande-Posa 《Cirugía espa?ola》2019,97(1):20-26
Objectives
To determine the incidence of incisional hernia (IH) in the extraction incision (EI) in colorectal resection for cancer. To analyze whether the location of the incision has any relationship with the incidence of hernias and whether mesh could be useful for prevention in high-risk patients.Methods
Retrospective review of the colon and rectal surgery database from January 2015 to December 2016. Data were classified into 2 groups, transverse (TI) and midline incision (MI), and the latter was divided into 2 subgroups (mesh [MIM] and suture [MIS]). Patients were classified using the HERNIAscore. Hernias were diagnosed by clinical and/or CT examination.Results
A total of 182 out of 210 surgical patients were included. After a median follow-up of 13.0 months, 39 IH (21.9%) were detected, 23 of which (13.4%) were in the EI; their frequency was lower in the TI group (3.4%) and in the MIM group (5.9%) than in the MIS group (29.5%; p = 0.007). The probability of developing IH in the MIS group showed an OR = 11.7 (95%CI: 3.3-42.0) compared to the TI group and 4.3 (IC 95%: 1.1-16.3) versus the MIM group.Conclusions
The location of the incision is relevant to avoid incisional hernias. Transverse incisions should be used as the first option. When a midline incision is needed, a prophylactic mesh could be considered in high risk patients because it is safe and associated with low morbidity. 相似文献45.
46.
47.
Bielik Peter Bonczek Ondřej Krejčí Přemysl Zeman Tomáš Izakovičová-Hollá Lydie Šoukalová Jana Vaněk Jiří Vojtěšek Bořivoj Lochman Jan Balcar Vladimir J. Šerý Omar 《Clinical oral investigations》2022,26(12):7045-7055
Clinical Oral Investigations - The aim of this study was the analysis of WNT10A variants in seven families of probands with various forms of tooth agenesis and self-reported family history of... 相似文献
48.
Estefany I. Medina-Reyes Carolina Rodríguez-Ibarra Daniel Díaz-Urbina Alejandro Déciga-Alcaraz Normal L. Delgado-Buenrostro Yolanda I. Chirino José Pedraza-Chaverri 《Journal of applied toxicology : JAT》2022,42(8):1411-1419
Food-grade titanium dioxide (E171) is widely used as a food additive, and it is known that after oral consumption, E171 is translocated into the bloodstream reaching the highest titanium level at 6 h. E171 is accumulated in some organs triggering toxicity, but the effects on the blood parameters after oral consumption have been less studied. Recently, evidence shows that oral exposure to E171 induces behavioral signs of anxiety and depression. The relation between blood alterations and psychiatric disorders has been previously demonstrated. However, the oral exposure to E171 effects on alterations in blood parameters and effects linked to alterations in animal behavior has not been explored. In this short communication, we aimed to investigate the effects of E171 on specific blood parameters (hematocrit, hemoglobin, number of erythrocytes, and leukocytes) and anxiety and compulsive-like behavior in males and females orally exposed to ~5 mg/kg for 4 weeks. The results showed that E171 decreased hematocrit and hemoglobin in male but not in female mice while leukocyte and erythrocyte count remained unaltered. Oral consumption of E171 decreased the levels of anxiety-like behavior in females but not in male mice, while compulsive-like behavior was increased in both male and female mice. 相似文献
49.
50.