全文获取类型
收费全文 | 1719篇 |
免费 | 128篇 |
国内免费 | 7篇 |
专业分类
耳鼻咽喉 | 8篇 |
儿科学 | 42篇 |
妇产科学 | 32篇 |
基础医学 | 233篇 |
口腔科学 | 38篇 |
临床医学 | 153篇 |
内科学 | 476篇 |
皮肤病学 | 23篇 |
神经病学 | 76篇 |
特种医学 | 40篇 |
外科学 | 149篇 |
综合类 | 6篇 |
一般理论 | 1篇 |
预防医学 | 162篇 |
眼科学 | 134篇 |
药学 | 135篇 |
中国医学 | 10篇 |
肿瘤学 | 136篇 |
出版年
2023年 | 10篇 |
2022年 | 28篇 |
2021年 | 49篇 |
2020年 | 20篇 |
2019年 | 36篇 |
2018年 | 47篇 |
2017年 | 32篇 |
2016年 | 30篇 |
2015年 | 38篇 |
2014年 | 46篇 |
2013年 | 63篇 |
2012年 | 85篇 |
2011年 | 113篇 |
2010年 | 54篇 |
2009年 | 51篇 |
2008年 | 95篇 |
2007年 | 93篇 |
2006年 | 101篇 |
2005年 | 88篇 |
2004年 | 97篇 |
2003年 | 81篇 |
2002年 | 83篇 |
2001年 | 49篇 |
2000年 | 49篇 |
1999年 | 48篇 |
1998年 | 17篇 |
1997年 | 15篇 |
1996年 | 15篇 |
1995年 | 12篇 |
1994年 | 9篇 |
1993年 | 12篇 |
1992年 | 21篇 |
1991年 | 26篇 |
1990年 | 31篇 |
1989年 | 20篇 |
1988年 | 19篇 |
1987年 | 15篇 |
1986年 | 13篇 |
1985年 | 16篇 |
1984年 | 13篇 |
1983年 | 14篇 |
1982年 | 12篇 |
1980年 | 5篇 |
1979年 | 5篇 |
1975年 | 5篇 |
1974年 | 12篇 |
1973年 | 10篇 |
1972年 | 12篇 |
1971年 | 11篇 |
1968年 | 6篇 |
排序方式: 共有1854条查询结果,搜索用时 0 毫秒
31.
Fernández Patón Matías Cerdá Alberich Leonor Sangüesa Nebot Cinta Martínez de las Heras Blanca Veiga Canuto Diana Cañete Nieto Adela Martí-Bonmatí Luis 《Journal of digital imaging》2021,34(5):1134-1145
Journal of Digital Imaging - Several noise sources, such as the Johnson–Nyquist noise, affect MR images disturbing the visualization of structures and affecting the subsequent extraction of... 相似文献
32.
33.
Association of ERG and TMPRSS2‐ERG with grade,stage, and prognosis of prostate cancer is dependent on their expression levels 下载免费PDF全文
34.
Laura Villarreal‐Martínez Jaime García‐Chvez Berenice Snchez‐Jara Aida Mashenka Moreno‐Gonzlez Janet Soto‐Padilla Efraín Aquino‐Fernndez Rogelio Paredes‐Aguilera Karla Maldonado‐Silva Cecilia Rodríguez‐Castillejos Ana Itamar Gonzlez‐vila María Mora‐Torres Hector Manuel Tiznado‐García Natalia Elizabeth Padilla‐Durn Nuria Citlali Luna‐Silva Eric Israel Gutirrez‐Jurez Jorge Nemi‐Cueto Claudia Sofia Gmez‐Gonzlez Ricardo De Len‐Figueroa Adela Lpez‐Miranda Mirna Guadalupe Ríos‐Osuna Edna Liliana Tamez‐Gmez Elio Aarn Reyes‐Espinoza Irving Armando Domínguez‐Varela Gerardo Gonzlez‐Martínez Elias Adn Godoy‐Salinas 《Haemophilia》2020,26(2):290-297
35.
Anne‐Maree Kelly Oene Van Meer Gerben Keijzers Justina Motiejunaite Peter Jones Richard Body Simon Craig Mehmet Karamercan Sharon Klim Veli‐Pekka Harjola Franck Verschuren Anna Holdgate Michael Christ Adela Golea Colin A. Graham Jean Capsec Cinzia Barletta Luis Garcia‐Castrillo Win S. Kuan Said Laribi 《Internal medicine journal》2020,50(2):200-208
36.
Azeez Butali Satoshi Suzuki Margaret E. Cooper Adela M. Mansilla Karen Cuenco Elizabeth J. Leslie Yasushi Suzuki Teruyuki Niimi Masahiko Yamamoto Gongorjav Ayanga Tudevdorj Erkhembaatar Hiroo Furukawa Kumiko Fujiwawa Hideto Imura Aline L. Petrin Nagato Natsume Terri H. Beaty Mary L. Marazita Jeffery C. Murray M.D. 《American journal of medical genetics. Part A》2013,161(5):965-972
37.
38.
M. Adela Valero M. Victoria Periago Ignacio Pérez‐Crespo Esperanza Rodríguez M. Jesús Perteguer Teresa Gárate Eva M. González‐Barberá Santiago Mas‐Coma 《Tropical medicine & international health : TM & IH》2012,17(5):630-636
Objectives To improve the diagnosis of human fascioliasis caused by Fasciola hepatica and Fasciola gigantica, we evaluated the diagnostic accuracy of an enzyme‐linked immunosorbent assay (ELISA), with Fasciola antigen from the adult liver fluke, for the detection of IgG against fascioliasis in human sera. Methods The sera of 54 fascioliasis cases, originating from three endemic areas, were used in this evaluation: (i) a hyperendemic F. hepatica area where humans usually shed a great number of parasite eggs in faeces (11 sera); (ii) an epidemic F. hepatica area where humans usually shed small amounts of parasite eggs (24 sera) and (iii) an overlap area of both Fasciola species and where human shedding of parasite eggs in faeces is usually scarce or non‐existent (19 sera). One hundred and sixty‐eight patients with other parasitic infections and 89 healthy controls were also analysed. Results The respective sensitivity and specificity of this assay were 95.3% (95% confidence intervals, 82.9–99.2%) and 95.7% (95% confidence intervals, 92.3–97.5%). No correlation between egg output and the OD450 values of the F. hepatica IgG ELISA test was observed. Conclusions This test could be used both as an individual serodiagnostic test for human fascioliasis when backed up by a compatible clinical history together with a second diagnostic technique for other cross‐reactive helminth infections, and in large‐scale epidemiological studies of human fascioliasis worldwide. 相似文献
39.
R. Lecumberri G. López Vivanco A. Font E. González Billalabeitia A. Gúrpide J. Gómez Codina D. Isla A. Galán I. Bover M. Domine V. Vicente R. Rosell E. Rocha 《Thrombosis research》2013
Introduction
The haemostatic system plays an important role in the process of cancer development and spread. Anticoagulants, mainly low molecular weight heparins, could prolong survival in cancer patients, particularly in patients with lung cancer, beyond prevention of thromboembolic events.Methods
In a multicenter, investigator-initiated, open-label, randomized, sequential study, 38 patients with newly-diagnosed, limited-stage small-cell lung cancer were randomized to receive standard chemoradiotherapy or the same therapy plus 3,500 IU daily of bemiparin for a maximum of 26 weeks. The primary outcome was progression-free survival.Results
The study was terminated early due to slow recruitment. Median progression-free survival was 272 days with chemoradiotherapy alone and 410 days in the bemiparin group; hazard ratio, 2.58 (95% confidence interval [CI], 1.15-5.80); p = 0.022. Median overall survival was 345 days with chemoradiotherapy alone and 1133 days in the bemiparin group; hazard ratio, 2.96 (95% CI, 1.22-7.21); p = 0.017. The rate of tumor response was similar in both study arms. There was no significant between-group difference in the rates of major bleeding. Toxicity related with the experimental treatment was minimal.Conclusion
The addition of bemiparin to first line therapy with chemoradiotherapy significantly increases survival in patients with newly-diagnosed, limited-stage small-cell lung cancer. (Funded by the Instituto Científico y Tecnológico, University of Navarra. ClinicalTrials.gov identifier: NCT00324558). 相似文献40.
Monetti M Usin MM Tabares S Gonzalez A Cabral HR Sembaj A 《Acta odontológica latinoamericana : AOL》2012,25(1):82-88
The purpose of this study was to investigate the relationship between P gingivalis, T forsythia, T denticola, P intermedia, and A. actinomycetemcomitans in the sulci or pockets of patients with gingivitis (G), mild chronic periodontitis (MiCP), moderate chronic periodontitis (MoCP) and severe periodontitis (SP), and the expression of TNF-alpha in gingival tissue associated with clinical parameters. Six patients with G, 7 with MiCP, 23 with MoCP and 7 with SP were recruited. Pathogens obtained from the sulci or pockets were identified by PCR, and expression of TNF-alpha from gingival tissue was analysed Probing depth (PD), clinical attachment level (CAL) and loss of bone were recorded. P gingivalis was detected at the following rates: 16.6% in subjects with G 57.1% in MiCP 57.8 % in MoCP and 58.1% in SP (p < 0.05). P intermedia was not identified in subjects with G A. actinomycetemcomitans was only identified in subjects with MoCP (31.5%) and SP (42.8%). T denticola and T forsythia were identified in all subject groups. Bacterial combinations were identified as follows: P denticola + P intermedia and PR intermedia + T forsythia were associated (p = 0.04, p = 0.02) with the presence of TNF-alpha mRNA in 20% and 25% of subjects, respectively. P gingivalis + A. Actinomycetemcomitans andA. actinomycetemcomitans + T forsythia were associated with severe PD and CAL, respectively. The association between the presence of P intermedia and expression levels of TNF-alpha was significant (p = 0.05). These results indicate that the proportion of patients with P gingivalis increases with the progression of disease. We observed that the presence of P intermedia may trigger the expression of TNF-alpha and cause a worsening of the patient's clinical status. 相似文献