玻璃体后脱离的超声诊断特点分析

目的探讨玻璃体后脱离的超声显像特点及其诊断价值。方法应用超声诊断技术对1002例患者进行检查，分析玻璃体后脱离的声像图特点和诊断依据。结果玻璃体后脱离的典型形态学改变表现为玻璃体内连续条带状回声，根据其是否与眼球后极部球壁回声相连分为完全性玻璃体后脱离和不完全性玻璃体后脱离。完全性玻璃体后脱离不与眼球后极部球壁回声相连，运动时表现为自眼球壁一侧向另一侧的波浪状推进的运动；不完全性玻璃体后脱离可与视盘或黄斑以及后极部任意一点或多点相固着，运动试验及后运动试验均阳性。玻璃体后脱离在彩色多普勒血流成像检查均无异常血流信号发现。结论超声检查可以准确地诊断玻璃体后脱离，为临床诊断和手术治疗提供客观依据．     

内镜下尼龙圈套扎治疗消化道息肉

消化道息肉是一种癌前病变 ,目前国内外学者广泛采用的治疗方法是高频电切除术[1] 。但该项技术对于宽基底或粗蒂的息肉存在着一定的不足和出血、穿孔的危险性。为了提高内镜下摘除息肉的治愈率 ,降低出血和穿孔的危险性 ,作者近来采用了尼龙圈套扎法对消化道不同部位的宽基底或粗蒂息肉进行了内镜下治疗 ,效果满意。现报告如下。1　临床资料1.1　一般情况　住院和门诊经内镜检出的消化道宽基底和粗蒂息肉病人 15例 ,男 7例 ,女 8例 ,年龄 2 8～ 77岁 ,平均 4 9 7岁 ,均有上腹不适或腹泻、便秘病史。1.2　内镜检查结果　息肉位于食管、直肠…     

Optos 200Tx广角眼底血管造影及其临床应用

广角眼底血管造影是近年来的影像检查新技术,可用于病变范围过大、传统眼底血管造影难以覆盖的患眼,可直观地显示周边部视网膜、脉络膜的血管结构.广角眼底血管造影分为接触式和非接触式两种.近期投入使用的欧堡全景200Tx激光扫描眼底成像系统(Optos 200Tx)是非接触式广角眼底血管造影的代表.它一次即可观察到200°眼底,无需散大瞳孔,且不接触患眼,操作简单、高效而安全,可用于累及周边部眼底的血管性疾病的诊断、鉴别诊断、治疗及随访方案的制定,如糖尿病视网膜病变、视网膜静脉阻塞、视网膜血管炎、葡萄膜炎、眼底肿瘤等.     

Local Delivery of C-myc Antisense Oligodeoxynucleotide by Gelatin Coated Platinium-Iridium Stent to Prevent Restenosis in a Normal Rabbit Carotid Artery

Restenosis occurred in 30%-40% of percutaneoustransluminal coronary angioplasty (PTCA). It isthought that vascular elastic recoil, remodeling,thrombosis and smooth muscle cells (SMCs)proliferation play a key role in the pathogenesis ofrestenosis. Because intracoronary stents avoided elasticrecoil and remodeling, it can significantly decreaserestenosis. However, in-stent restenosis remains amajor problem, occuring in 15% -20% of theseprocedures [1].How to prevent restenosis has been to amajo…     

中西医结合治疗幽门螺杆菌相关性胃炎疗效观察

慢性胃炎因病因各异而分为不同类型 ,治疗方法也各有不同 ,但目前认为大多数慢性胃炎的主要病因是幽门螺杆菌 (Hp)感染[1] ,称为 Hp相关性胃炎。西药有许多根除 Hp的方案 ,但由于抗生素的毒副作用 ,耐药性的产生 ,以及同时在改善消化不良症状方面的作用有限 [2 ] ,影响其临床疗效的发挥。我们从 1 997～ 2 0 0 2年采用法莫替丁加中医辨证治疗 Hp相关性胃炎 ,效果满意 ,现报告如下。1　资料与方法1 .1　一般资料 :全部资料均来自本院住院和门诊患者 ,经胃镜检查 ,同时取幽门前区粘膜作快速尿素酶检测 (试剂盒由杭州临科生物技术有限公司提…     

Treatment of retinal vein occlusion in rabbits with Fufang XueShuan Tong

Background Retinal vein occlusion (RVO) is one of the most common causes of visual loss. Many approaches have been tried to treat central retinal vein occlusion (CRVO), and branch retinal vein occlusion(BRVO) with various results. However, there is no definite has been found and limited evidence to support the interventions currently used to treat it. The aim of this study was to assess the effectiveness of the traditional medicine Fufang XueShuan Tong (FXST) in treating experimentally created RVO. Method First, RVO model was induced in forty-four pigmented rabbits through photocoagulation following injection of rose Bengal. The rabbits were divided into four groups based on the dose of FXST administered (212mg/kg,424mg/kg 848mg/kg and control group). The rabbits were observed for four weeks after the procedure, using color fundus photography, fundus fluorescein angiography (FFA ) and electroretinograms (ERG) examination; VEGF, IL-6, NO levels in the vitreous and histopathologic evaluation. Results The obstructed vessels in the treatment groups reopened or anastomosed faster than those in the control group (p<0.05). The amplitude of max b-mave and the oscillatory potential were significantly higher in the treatment groups than in the control group(p<0.01). At both two weeks and four weeks VEGF, IL-6 levels in the vitreous were significantly decreased in the treatment groups(p<0.01), while NO levels were significantly elevated(p<0.01). At the same time, histopathologic evaluation showed different retinal neuroepithelium structures in the different groups, immunoreactivity of VEGF was greater in the control group than in the treatment groups. Conclusion FXST was helpful in reconstructing retina vessels in the RVO model , protecting retina structure and improving visual function, and could inhibit the NV factor.     

2011年至2021年中国葡萄膜黑色素瘤研究现状及进展

葡萄膜黑色素瘤（UM）是成人中最常见的原发性眼内恶性肿瘤。UM在亚洲地区的发病率低于欧美国家,但亚洲UM患者的发病年龄比欧美国家人群更早。随着近年来经济生活水平的提高,UM作为一种罕见的眼内肿瘤,已逐渐被更多人认识。近10年来,我国UM研究呈现出数量多、发展快的特点。其中以非编码RNA为代表的分子遗传学方向、UM潜在抗...     

磁共振成像检查对脉络膜黑色素瘤的诊断价值

目的：通过对磁共振成像（MRI）检查对脉络膜黑色素瘤诊断的敏感度和特异度的分析,评价MRI检查对脉络膜黑色素瘤的诊断价值。方法：对26例患者（28眼）术前进行MRI检查,结合病理诊断,应用SPSS12.0软件对超声检查结果进行统计学分析。结果：MRI检查对脉络膜黑色素瘤诊断的敏感度和特异度分别为85.7%和66.7%,MRI检查结果与病理诊断具有较好的一致性（Kappa值=0.494,P=0.010）。结论：MRI检查对诊断脉络膜黑色素瘤具有较好的诊断价值。     

氯吡格雷对冠心病患者PCI前后CD40配体的影响

目的：探讨冠心病患者血小板膜CD40配体（CD40L）和血清可溶性CD40配体（sCD40L）在冠脉内介入治疗（PCI）前后的变化及其临床意义。方法：选择30例经冠状动脉造影确诊为冠心病的患者,接受规范的抗心绞痛治疗,术前给予氯吡格雷75mg／d,行PCI术前及术后6h,采用流式细胞仪测定患者活化血小板CD40L的表达率,采用酶联免疫吸附法测定血清sCD40L的含量。结果：30例冠心病患者PCI术前血小板CD40L的表达率水平为（3．73±2．15）％,术后6h为（2．46±0．90）％,较术前显著降低（P〈0.01）。PCI术前血清sCD40L的含量为（11．72±4．25）ng／ml,术后6h为（9．98±3．32）ng／ml,较术前显著降低（P〈0.01）。结论：氯吡格雷降可低冠心病患者PCI术后早期血清和血小板膜CD40L的含量和表达,预防血栓栓塞事件发生。