恶性肿瘤病人血清SIL－2R与红细胞免疫功能测定及临床意义

本文对９１例恶性实体瘤病人的血清ＳＩＬ－２Ｒ、ＲＢＣ－Ｃ３ｂＲＲ、ＲＢＣ－ＩＣＲ进行测定，结果显示：恶性肿瘤病人血清ＳＩＬ－２Ｒ增高，ＲＢＣ－ＩＣＲ增多，而ＲＢＣ－Ｃ３ｂＲＲ降低（Ｐ＜０．００１）；不同类型恶性肿瘤病人之间，血清ＳＩＬ－２Ｒ、ＲＢＣ－Ｃ３ｂＲＲ及ＲＢＣ－ＩＣＲ相比无显著差异性（Ｐ＜０．０５）；血清ＳＩＬ－２Ｒ水平与ＲＢＣ－Ｃ３ｂＲＲ呈负相关（ｒ＝－０．５１，Ｐ＜０．０５），与ＲＢＣ－ＩＣＲ呈正相关（ｒ＝０．４８，Ｐ＜０．０５）。这表明：恶性肿瘤病人血清ＳＩＬ－２Ｒ升高，红细胞免疫功能低下，其两者的变化可能与恶性肿瘤的发生、发展有密切关系，值得临床进一步研究。     

β-内啡肽对正常人外周血单核细胞抗原提呈能力的影响

β-内啡肽(β-EP)是一种阿片样神经肽,当中枢神经系统受某种刺激时可将其释放入血。本研究的结果表明,当正常人单核细胞(Mon)预先与纯化蛋白衍生物(PPD)及3.2×10~(-3)mol/L的β-EP共同温育18小时后,Mon对PPD的抗原提呈能力(APCP)显著增强(P<0.01),而于相同条件下,加入7.3×10~(-7)mol/L的纳络酮(Nal)时,β-EP对Mon的APCP的增强作用被对消(P>0.05)。以上结果说明β-EP可能是通过作用于阿片受体而增强Mon的APCP的。     

晚期前列腺癌的治疗50例报告

1996年1月～2001年12月作者应用去势术+氟他胺治疗晚期前列腺癌50例,疗效满意,现报告如下.     

老龄小鼠巨噬细胞激活前后酶活性的变化

目的探讨老龄小鼠腹腔巨噬细胞（ＭＣＰ）受刺激前后的功能变化。方法以肉汤为培养基刺激小鼠腹腔Ｍ，３ｄ后测定Ｍ内ＡＣＰ、ＬＤＨ和ＳＤＨ活性。结果老龄小鼠受刺激后ＡＣＰ、ＳＤＨ活性升高，水平较青龄组低（Ｐ＜０．０５）。结论老龄组Ｍ应激能力低于青龄组。     

多普勒超声测定精索蔓状静脉管径与生育力的相关性

本文通过40例精索静脉曲张不育症患者的多普勒超声检查,结合睾丸容积、精液分析和性激素测定进行曲张程度和生育力相关分析.结果表明:精索静脉管径与临床分级呈正相关,与睾丸容积和生育力指数呈负相关.我们认为多普勒测定精索静脉管径具有诊断和程度评估价值.亦可能成为推测精索静脉返流存在时间的一种方法.     

冠心病与高胰岛素血症关系探讨

冠心病诸多致病因素中,除了公认的高胆固醇血症、高血压和吸烟等危险因素外,糖尿病亦是重要的危险因素。研究表明各种类型的糖尿病都存在着高胰岛素血症,且冠心病的发病率均较正常者为高。高胰岛素血症在冠心病的发病中起着十分重要的作用,是一个潜在的致冠心病危险因素。国内尚少有这方面报道,本研究旨在探讨冠心病(CHD)患者的血清胰岛素(SI)水平及其与冠心病其他已知因素的关系。     

氨力农治疗各种心力衰竭疗效观察

氨力农治疗各种心力衰竭疗效观察福建省心血管病研究所陈群，胡锡衷，刘文林近期，我所应用江苏宝应制药厂和山东齐鲁制药厂生产的氨力农针剂治疗各种原因引起的心力衰竭患者３１例，疗效较满意，报道如下。一、临床资料住院治疗的心力衰竭患者３１例，男性１２例，女性１...     

普鲁卡因和利多卡因在心脏停搏液中的作用(心功能、心肌酶和超微结构评价)

用离体做功鼠心模型观察并比较了普鲁卡因和利多卡因对钾停搏液作用的影响。实验分为四组：基础停搏液组、含１ｍｍｏｌ／Ｌ普鲁卡因停搏液组、含１ｍｍｏｌ／Ｌ利多卡因停搏液组和含０．２５ｍｍｏｌ／Ｌ利多卡因停搏液组。观察各组心脏缺血后复灌期的功能恢复百分率、心肌酶漏出量、心肌水含量和心肌超微结构变化。结果表明，１ｍｍｏｌ／Ｌ普鲁卡因对停搏液的心肌保护作用无明显影响，而０．２５ｍｍｏｌ／Ｌ和１ｍｍｏｌ／Ｌ利多卡因均表现为心肌损害作用，心功能恢复抑制与心肌损害的加重有关。０．２５ｍｍｏｌ／Ｌ利多卡因的损害作用较轻，但恢复灌后的心肌水肿程度明显加重。     

INTRACARDIAC REPAIR OF ATRIOVENTRICULAR CANAL MALFORMATIONS CLINICAL ANALYSIS AND FOLLOW-UP STUDY

From March 1972 to June 1982, a consecutive series of 81 patients with atrioventricular canal (a-v canal) malformations underwent intracardiac repair. Among them, seven were ostium primum defects, 70 partial form defects and four complete form defects. Twenty-one patients had associated cardiovascular anomalies with an incidence of 25.9To. Operation was performed under total body per fusion. A constant finding at the operation was primum type low atrial septal defect (ASD). At operation, the ASD was repaired routinely by a dacron patch. Superficial stitches were employed to prevent conduction system damage. Mitral cleft on the aortic leaflet was found in 74 patients, perforation of the tricuspid valve in three and accessory chordae tendineae in two. For the four cases of complete a-v canal, jet was palpated at the ventricular level. For repair of the mitral cleft, two different methods, complete closure and partial approximation of the cleft, were utilized to leave one third of the cleft at its free margin intact. There were four postoperative hospital deaths, all occurring in the category of partial form. The overall mortality was 4.9To. Seventy patients were followed up, showing that the late results in patients with mild-preoperative mitral insufficiency were much better than that in patients with significant insufficiency, and that partial approximation of the mitral cleft might be the method of choice in most cases.