虚中夹瘀论治老年性骨质疏松症38例

骨质疏松症又称骨质缺少症,因骨质吸收超过骨质形成所致。老年性骨质疏松多为原性性骨质疏松。笔者自1992年以来以虚中夹瘀论治观点采用益肾健脾、活血通络标本同治,效果满意。1 临床资料 本组38例,男13例,女25例;男女比例约1∶2。年龄50至70岁之间,平均约60岁。病程最短半年,最长五年。症状主要表现为全身     

相邻两节段脊髓型颈椎病两种颈前路手术方式的比较

目的 对比分析前路颈椎体次全切除钛网植骨融合术（ACCF）和前路颈椎间盘切除融合器融合术（ACDF）两种手术方式治疗相邻两节段脊髓型颈椎病的疗效.方法 对行相邻两节段脊髓型颈椎病手术治疗的63例患者的临床资料和影像学资料进行回顾性分析,其中ACCF组34例,ACDF组29例.比较2组的手术时间、住院时间、术中出血量、脊髓神经功能JOA评分、颈椎生理曲度、椎体高度、融合节段稳定性及融合率.结果 与ACCF组比较,ACDF组手术时间明显缩短、术中出血量明显减少（P＜0.05或P＜0.01）,颈椎生理曲度及椎体高度均明显改善（P＜0.05或P＜0.01）.2组间住院时间、JOA评分、融合节段稳定性及末次随访融合率差异无统计学意义（P＞0.05）.结论 ACCF加钛网、ACDF加融合器均是治疗相邻两节段脊髓型颈椎病的有效术式,ACDF加融合器术在缩短手术时间、减少术中出血量、维持颈椎生理曲度及椎体高度方面有明显优势.     

无锡市灭蟑工作技术措施

近几年来，为了更好地贯彻全国爱卫会有关文件精神，巩固我市“灭蟑先进城市”取得的成果，我市常年坚持开展灭蟑活动，蟑螂密度明显下降。今年为使我市顺利通过“灭蟑先进城市”复查达标，特制订灭蟑工作技术措施。     

超选择性肾动脉造影在急性肾出血介入治疗中的应用价值

目的探讨超选择性肾动脉造影在肾出血介入治疗中的应用价值。方法回顾性分析本院2009年5月至2011年12月68例肾出血血尿患者的临床资料,其中医源性肾出血45例,外伤性肾出血14例,肾肿瘤出血9例,所有病例均行肾动脉主干造影及介入栓塞治疗,部分行超选肾段动脉造影。结果肾动脉造影52例阳性,16例阴性,16例阴性患者再行超选择性肾段动脉造影显示肾段以下动脉出血者15例。结论超选择性肾动脉造影是诊断肾动脉小分支出血最可靠方法,对介入诊治有着重要的意义。     

生物不育灭鼠饵剂现场鼠类控制效果研究

[目的]研究生物不育灭鼠饵剂在现场大规模应用时,对鼠类的控制效果. [方法]在不育剂试验区采用首次足量投放,第2次等量补充的方法投放生物不育灭鼠饵剂后,检查鼠对该饵剂的拖食情况,并在投放后第1、3、4、6、9、12个月测定鼠密度,分类后剖检成年鼠的生育能力,同时设抗凝血灭鼠剂对照区和自然对照区. [结果]现场23d内鼠类对不育剂保持较好的适口性,平均拖食率为14.37%.3个月后平均鼠密度与灭前比较下降75.76%,年平均下降率为41.41%,全年鼠密度处于较低水平.投饵后3、4、6个月的鼠密度与自然对照区比较,相关密度指数(RPI)值为23.52、19.27和48.51.不育剂试验区解剖鼠类的繁殖率为7.69%,没有发现具有繁殖能力的雌鼠;而抗凝血灭鼠剂对照区、自然对照区和投药前的鼠的繁殖率分别为44.44%、33.33%和31.57%. [结论]现场应用研究证明,该生物不育灭鼠饵剂具有良好的适口性,安全环保,与常规抗凝血灭鼠剂相比,在有效控制种群数量上具有重要价值.     

老年腰椎间盘突出症的手术治疗

腰椎间盘突出症是临床常见病,多见于青壮年。随着人口老龄化,60岁以上腰椎间盘突出症患者逐步增多。由于老年腰椎退变明显,其病理特点与手术方式有别于青壮年患者。我院自1995年5月至2004年10月手术治疗60岁以上老年腰椎间盘突出患者65例,报道如下。1临床资料1.1一般资料本组男     

无锡市火车站抗击“非典”时期对流动人员监控的措施

无锡市地处江苏南部、中国经济发达的长江三角洲中部 ,交通发达、风景秀丽 ,是中国十五个经济中心城市和十个重点旅游城市之一。总人口数5 0 8万 ,其中长住超过三个月以上的外来人口达74.0 5万人 ,短期流动人口达 40万以上。在抗击“非典”过程中 ,抓好出入境人员及来(返 )锡人员的监测管理是事关我市夺取抗击“非典”全胜的重要步骤。火车站是无锡市的重要窗口门户。根据每天出入境无锡的人数多 ,来往人员及来地非常复杂的特点。无锡市对来 (返 )锡人员作出了如下六点要求 :一、凡从非典型肺炎疫情发生地区返锡或来锡人员 ,必须到指定单位…     

经皮颈静脉穿刺肝静脉测压术34例

目的 探讨经皮颈静脉穿刺肝静脉测压术在门脉高压诊治中的应用价值.方法 回顾性分析本院2009年1月至2012年5月收治的34例门脉高压症患者的临床资料,所有病例均行经皮颈静脉穿刺肝静脉测压术.结果 所有病例分别测得自由肝静脉压(FHVP)、肝静脉楔压(WHVP),差值为肝静脉压力梯度(HVPG),HVPG≤6 cmH2O7例(1cmH2O=0.098 kPa),6～16 cmH2O 13例,＞16 cmH2O 14例.结论 肝静脉压力梯度测定在门静脉高压诊治中具有重要的指导意义.     

苦参碱对海马脑片电信号及氨基酸神经递质的作用

BACKGROUND： Studies on electrical signals of hippocampal brain slices in vivo have shown that matrine inhibits benzylpenicillin sodium-induced activation of neuronal signal transduction.
OBJECTIVE： To verify the inhibition effect of matrine on activation of electrical signals in rat brain slices and the role rnatrine plays in hippocampal amino acid transmitter release.
DESIGN, TIME AND SETTING： The in vitro, neurophysiological, controlled experiment was performed in the Zhejiang Province Key Laboratory of Cardio-cerebrovascular Disease and Nerve System Drugs Appraisement and Chinese Traditional Medicine Screening and Research between July 2003 and May 2004. The in vivo, neuronal, biochemical experiment was performed in the Zhejiang Province Key Laboratory of Chinese Traditional Medicine Quality Standardization from July 2005 to December 2006.
MATERIALS： Forty healthy, Sprague Dawley rats, 7-8 weeks old, and 120 healthy, ICR mice, 5-6 weeks old, were included in this study, irrespective of gender. Matrine powder was provided by the National Institute for the Control of Pharmaceutical and Biological Products, China. Matrine injection was purchased from Zhuhai Biochemical Pharmaceutical Factory, China. Penicillin was bought from Shijiazhuang Pharmaceutical Group Co., Ltd., China.
METHODS： （1） Rats were randomly assigned to four groups： control, penicillin model, and matrine high-dose and low-dose, with 10 rats in each group. The control group was perfused with artificial cerebrospinal fluid. In the remaining three groups, hippocampal brain slices were perfused with normal artificial cerebrospinal fluid containing 1 × 106 U/L penicillin for the first 10 minutes. The penicillin model group received artificial cerebrospinal fluid for an additional 30 minutes, while the matrine high-dose and low-dose groups received 0.1 g/L and 0.05 g/L matrine, respectively, for an additional 30 minutes. （2） Mice were randomly assigned to four groups （n = 30）. The matrine high-, medium-, and low-dose groups were separately injected with 58.5, 39.0, and 19.5 mg/kg matrine via caudal vein, respectively. No intervention was administered to the normal group.
MAIN OUTCOME MEASURES： The field potential value in the CA1 region of penicillin-induced rat hippocampal brain slices was analyzed using the evoked field potential technique; chromatography was utilized to determine y-aminobutyric acid and glutamic acid content in the mouse hippocampus.
RESULTS： （1） Both 0.1 g/L and 0.05 g/L matrine reduced the number of evoked field potentials in the penicillin-induced rat hippocampal brain slices （P 〈 0.05 or P 〈 0.01 ）. In addition, 0.1 g/L matrine led to a reduction of evoked field potential amplitude （P 〈 0.05）. （2） Compared with normal mice, γ-aminobutyric levels were dramatically increased at 20 minutes after high-dose matrine treatment （P 〈 0.05）. In addition, significantly increased γ-aminobutyric acid levels were observed at 40 minutes after medium- and low-dose matrine treatments （P 〈 0.05 or P 〈 0.01 ）. The glutamic acid/γ-aminobutyric acid ratio was significantly less at 20 minutes after high-dose matrine treatment compared with the normal mice group （P 〈 0.05）.
CONCLUSION： Matrine exerts a central inhibitory effect via increased inhibitory neurotransmitter γ-aminobutyric acid levels in the hippocampus.     

中药外敷治疗膝关节骨性关节炎90例

我院自2000年以来,采用自制中药膏剂外敷治疗老年性膝关节骨性关节炎90例,疗效满意,现报道如下。1临床资料全部176例均为我院门诊患者,其中中药治疗组90例,男40例,女50例;年龄55岁~90岁,平均68.5岁。西药对照组86例,男39例,女47例;年龄53岁~89岁,平均65.4岁。病程最长20a,最短1