推拿配合刺络拔罐治疗胫骨疲劳性骨膜炎33例

目的:观察推拿配合刺络拔罐治疗胫骨疲劳性骨膜炎的疗效。方法:运用推拿配合刺络拔罐治疗,用长海痛尺评估法进行疼痛评估。结果:连续治疗2个疗程(20天,每天1次)后,患者疼痛显著减轻。结论:推拿配合刺络拔罐治疗胫骨疲劳性骨膜炎有显著疗效。     

控释地诺前列酮栓用于羊水过少引产对母婴的影响及护理

目的观察欣普贝生(控释地诺前列酮阴道栓剂)用于足月妊娠羊水过少引产时临床疗效、安全性及护理方法。方法单胎头位羊水过少的初产妇128例,随机分为观察组(欣普贝生组)63例,对照组(缩宫素组)65例,分别于给药后4h、8h、12h进行宫颈Bishop评分,观察两组孕妇的用药到分娩的时间、分娩方式、对母婴的影响。结果观察组用药后促宫颈成熟效果、用药到分娩的时间、阴道分娩率均优于对照组,对母婴影响无显著性差异。结论欣普贝生应用于足月妊娠羊水过少的产妇引产效果明显,安全性高。用药过程中,加强护理和观察,能有效缩短产程时间,提高阴道分娩的信心,能减低产程中因社会因素剖宫产,减低剖宫产率。     

无痛人流患者健康教育的临床路径效果观察

目的探讨临床护理路径（CNP）在无痛人流患者健康教育中应用效果。方法选择2009年9～12月在我院门诊行无痛人流或清宫手术的患者400例随机分为CNP组200例（试验组A组）,常规护理组200例（对照组B组）,对照组采用传统健康教育方法,试验组采用临床路径标准模式进行健康教育。观察各两组患者对健康知识掌握和对护理的满意度有无统计学差异。结果实验组患者健康教育达标率为91.5%,对照组为66%,差异有统计学意义（P〈0.05）。实验组患者满意度为96.5%,对照组为77%,差异有统计学意义（P〈0.05）。结论 CNP在无痛人流中的应用,提高了教育效果,提高了患者的健康意识,增加患者对护理的满意度,是一种有效的健康教育方法。     

骨髓增生异常综合征患者的护理

目的 探讨骨髓增生异常综合征(MDS)患者的治疗观察及护理措施.方法 对52例骨髓增生异常综合征患者实施全程护理干预.结果 经精心治疗及护理,部分病例较快获临床好转,部分病例获完全缓解并保持稳定出院.疾病缓解率及护理效果满意,未见相关并发症发生.结论 有效的治疗观察及护理干预措施,对提高疗效,提高疾病缓解率,改善患者生活质量有着重要作用.     

细胞色素P450 CYP1A1基因多态与鼻咽癌易感性的关联分析

Objective To investigate the association between CYP1A1 gene polymorphisms and susceptibility of nasopharyngeal carcinoma in Cantonese nuclear families through family-based association study. Methods A total of 457 Cantonese nuclear families, consisting of 2134 members, were recruited as subjects. Each family included two parents and at least one offspring with nasopharyngeal carcinoma. Two single nucleotide polymorphisms (SNP) in CYP1A1 named m1 (rs4646903) and m2 (rs1048943) , were genotyped by PCR-RFLP assay and verified by directly sequencing. The genotype data were analyzed with family-based association test (FBAT) software to check the linkage and association between the two genetic markers and susceptibility of nasopharyngeal carcinoma. Results FBAT analysis showed that the minor allele frequencies (MAF) of the two SN P were 0. 442 (C) and 0. 339 (G) respectively. For m1 polymorphism in CYP1A1 gene was not significantly associated with nasopharyngeal carcinoma in our study population whether stratified with VCA-IgA or not (without stratification : X2=2. 399, P=0. 301 ; with stratification : Iow-titer group (VCA-IgA<1 : 80), MAF=0. 457 (C), X2=1.221, P=0.543 ; high-titer group (VCA-IgA ≥1 : 80), MAF=0. 427 (C), X2=2. 832, P=0. 243). For m2 polymorphism, when VCA-IgA<1 : 80, the G allele showed decreased transmission under additive and dominant model (MAF=0. 347 (G) ; Zadditive=-2. 120,Padditive=0. 034;Zdominant=-2. 303,Pdominant=0.021)and a boundary P value was got with global statistic (X2=5. 394, P=0. 067). Haplotype TG (0. 057), constructed by ml and m2, might decrease nasophargneal carcinoma risk (Z=-2. 002,P=0. 045). A boundary P value was also got with global statistic (X2=7. 067 ,P=0. 070). Conclusion There was no statistical significance between ml polymorphism and susceptibility of nasopharyngeal carcinoma in Cantonese nuclear families. And this study showed that m2 polymorphism might associated with the decrease of nasopharyngeal carcinoma in Cantonese nuclear families.     

推拿配合刺络拔罐治疗胫骨疲劳性骨膜炎33例

目的：观察推拿配合刺络拔罐治疗胫骨疲劳性骨膜炎的疗效。方法：运用推拿配合刺络拔罐治疗．用长海痛尺评估法进行疼痛评估。结果：连续治疗2个疗程（20天，每天1次）后，患者疼痛显著减轻。结论：推拿配合刺络拔罐治疗胫骨疲劳性骨膜炎有显著疗效。     

患者特检期间的人性化护理

随着时代的变迁和社会的不断发展，社会对医院的服务也提出了更高的要求，也越来越要求实施人性化服务。为适应新形势下患者的需求，我院于2003年1月设临床服务中心，其中一项服务项目是护送特检患者。近1a来笔者护送特检患者5540例，兹将特检护送过程中人性化护理总结如下。     

细胞色素P450 CYP1A1基因多态与鼻咽癌易感性的关联分析

Objective To investigate the association between CYP1A1 gene polymorphisms and susceptibility of nasopharyngeal carcinoma in Cantonese nuclear families through family-based association study. Methods A total of 457 Cantonese nuclear families, consisting of 2134 members, were recruited as subjects. Each family included two parents and at least one offspring with nasopharyngeal carcinoma. Two single nucleotide polymorphisms (SNP) in CYP1A1 named m1 (rs4646903) and m2 (rs1048943) , were genotyped by PCR-RFLP assay and verified by directly sequencing. The genotype data were analyzed with family-based association test (FBAT) software to check the linkage and association between the two genetic markers and susceptibility of nasopharyngeal carcinoma. Results FBAT analysis showed that the minor allele frequencies (MAF) of the two SN P were 0. 442 (C) and 0. 339 (G) respectively. For m1 polymorphism in CYP1A1 gene was not significantly associated with nasopharyngeal carcinoma in our study population whether stratified with VCA-IgA or not (without stratification : X2=2. 399, P=0. 301 ; with stratification : Iow-titer group (VCA-IgA<1 : 80), MAF=0. 457 (C), X2=1.221, P=0.543 ; high-titer group (VCA-IgA ≥1 : 80), MAF=0. 427 (C), X2=2. 832, P=0. 243). For m2 polymorphism, when VCA-IgA<1 : 80, the G allele showed decreased transmission under additive and dominant model (MAF=0. 347 (G) ; Zadditive=-2. 120,Padditive=0. 034;Zdominant=-2. 303,Pdominant=0.021)and a boundary P value was got with global statistic (X2=5. 394, P=0. 067). Haplotype TG (0. 057), constructed by ml and m2, might decrease nasophargneal carcinoma risk (Z=-2. 002,P=0. 045). A boundary P value was also got with global statistic (X2=7. 067 ,P=0. 070). Conclusion There was no statistical significance between ml polymorphism and susceptibility of nasopharyngeal carcinoma in Cantonese nuclear families. And this study showed that m2 polymorphism might associated with the decrease of nasopharyngeal carcinoma in Cantonese nuclear families.     

经PTCD行胆道内支架植入治疗高龄恶性梗阻性黄疸的疗效观察及护理

目的:观察经PTCD行胆道内支架植入治疗高龄恶性梗阻性黄疸病者的疗效及总结护理要点.方法:对10例75岁以上患有恶性肿瘤合并梗阻性黄疸高龄患者采用经PTCD行胆道内支架植入的治疗,在治疗观察的过程中给予对症护理.结果:病人治疗前皮肤、巩膜重度黄染,肝功能严重损害,伴腹胀、纳差,经采用这种方法病人一周后皮肤巩膜黄染明显消退,腹胀缓解,肝功能改善,食欲提高.结论:应用经PTCD行胆道内支架植入治疗高龄恶性梗阻性黄疸,给予对症的护理,患者可明显改善黄疸及伴随症状,且促进高龄患者康复较快.     

恙虫病并发多器官功能障碍综合征1例

恙虫病是携带恙虫病立克次体(东方立克次体)的恙螨幼虫媒介传播的急性传染病,其临床特征为持续高热、毒血症症状、皮疹、焦痂、淋巴结肿大等.