Efficacy of Yanshu injection (a compound Chinese traditional medicine) combined with concurrent radiochemotherapy in patients with stage Ⅲ nasopharyngeal carcinoma

Objective To evaluate the efficacy and toxicity of Yanshu injection (a compound Chinese traditional medicine from Sophora flauescens Ait) combined with concomitant radiochemotherapy in patients with stage Ⅲ nasopharyngeal carcinoma. Methods Sixty patients with stage Ⅲ nasopharyngeal carcinoma were randomized into Yanshu group and control group (n =30, each). Patients in the Yanshu group received Yanshu injection in addition to intensity modulated radiation therapy ( IMRT) and concomitant chemotherapy, and those in the control group were treated with IMRT and concurrent chemotherapy. Results The 1-year, 2-year, 3-year and 4-year overall survival rates were 100%, 93.3%, 86.7% , 80. 0% for Yanshu group, and 96. 7% , 90. 0% , 83. 3% , 76. 7% for the control group, respectively, with no significant difference between the two groups ( P = 0.565). The 1 -year, 2-year, 3-year and 4-year progression-free survival rates were 96.7% , 90. 0% , 83. 3% , 70. 0% for Yanshu group, and 90.0% , 86.7% , 76. 7% , 66. 7% for control group, respectively, with no significant difference (P = 0.554). However, the reaction of mucosa of oral cavity, myelosuppression and thrombocytopenia in the Yanshu group were significantly lower than that in the control group (P < 0. 05). The quality of life of the patients in the Yanshu group was significantly higher than that in the control group ( P < 0. 05 ). Conclusions Yanshu injection combined with radiochemotherapy in patients with stage Ⅲ nasopharyngeal carcinoma show a good efficacy and can reduce the side effects of radiochemotherapy of nasopharygeal carcinoma, and improve the quality of life of the patients.     

急性胃炎的护理52例

急性办炎是多种病因引起的急性胃粘膜症,临床常急性发病,可有明显上腹部症状,内镜检查可见胃粘膜充血、水肿、出血、糜烂等一过性病变. 1 临床资料 1.1 一般资料 2008年10月住院患者52例,其中男性40例,女性42例,年 龄23-72岁.     

老年慢性阻塞性肺疾病患者锻炼行为感知现状及影响因素分析

目的 评估老年慢性阻塞性肺疾病 (chronic obstructive pulmonary disease,COPD) 患者锻炼行为感知水平,并分析其影响因素。方法 采用方便抽样法,选取2018年12月—2019年6月于济南市4所三级甲等医院住院的207例老年COPD患者作为调查对象。采用一般资料调查表、锻炼益处及障碍量表、呼吸困难信念问卷、COPD患者自我效能量表和社会支持评定量表进行调查。 结果 207例老年COPD患者锻炼益处及障碍量表得分为 (127.34±11.71) 分,锻炼行为感知与恐惧活动信念呈负相关 (r=-0.469,P<0.001),与自我效能和社会支持均呈正相关 (r=0.412,P<0.001;r=0.247,P<0.001) 。多元线性回归分析结果显示,恐惧活动信念、自我效能、社会支持及患病前体力活动情况是锻炼行为感知的影响因素。 结论 老年COPD患者的锻炼行为感知水平有待提高。加强对COPD患者及其家属的运动康复教育和指导,帮助患者消除或降低对体力活动的恐惧,提高自我效能感和获取、利用社会支持的能力,有利于改善其对锻炼行为的感知。     

冬季宝宝防治感冒6大锦囊

王女士的宝宝刚满三周岁，机灵的大眼睛甚是招人喜爱。全家人都视为掌心里的宝，在这伴着雪花和呼呼北风的冬天，王女士对宝宝更加精心呵护，穿了一层有一层，毛衣、棉马夹、小棉祅、羽绒服、棉裤外面套棉裤。每天给宝贝穿得像个小胖熊熊，摇摇摇晃晃的就出了家门。但精心呵护也没有避免小宝宝遭遇感冒威胁。王女士无奈地慨叹，我这么精心保护宝宝，她也总是要病上场。唉，我真是怕了这北方的冬天！     

肺和呼吸

一个成年人一昼夜要吸入十多立方米的氧气和呼出同样数量的二氧化碳,这些气体足以装满一辆大卡车,如此浩大的工程都由肺来完成,那么,肺具有怎样的特殊结构?呼吸运动又为何能周而复始,有节律地进行呢? 让我们先来看看肺的情况吧。肺左右各一,位于胸腔两侧,胸腔的中央为纵膈和心脏。左侧肺分为上下两部分(叶),右侧肺分为上、中、下三叶,每个肺叶     

毛细管聚合酶链反应快速诊断孕妇沙眼衣原体感染

毛细管聚合酶链反应快速诊断孕妇沙眼衣原体感染裘国强，杨懿霞，酆豫增沙眼衣原体（ＣＴ）感染的实验室诊断以往采用宫颈棉试子取材涂片，经姬姆萨染色查包涵体等方法，因敏感性差，已较少采用。近年来，国内外学者报道，采用直接荧光抗体法（ＤＦＡ）检测，酶免疫反应，...     

围产保健中危险因素流行规律的研究

对1992年7月1日～1993年6月30日在我院产前检查及分娩的995例孕产妇进行了回顾性的调查。结果孕期高危妊娠发生率为78.09％,产时危险因素发生率为14.37％,产后为3.82％。并分析了各阶段主要危险因素的流行情况。