地塞米松、降钙素基因相关肽、THP对系膜细胞与IL－1相互作用的影响

应用分子生物学技术研究表明地塞米松，降钙素基因相关肽（ＣＧＲＰ），ＴＨＰ三者在不同环节上拮抗了ＩＬ一１的作用，为在临床上治疗肾小球炎症提供了实验依据。     

制约中专图书馆发展因素探析

改革开放 2 0多年来 ,中国社会的发展举世瞩目 ,中等专业教育也取得了长足发展 ,现代化的中专图书馆建筑如雨后春笋般拔地而起。然而 ,相对图书馆办馆条件的变化来说 ,图书馆业务工作的水平和服务质量却并无明显提高。面对入世和中专“二次创业”的来临 ,图书馆人只有客观、正确、积极地分析把握面临的形势 ,才能找到存在的问题 ,找准对策 ,找好出路 ,发展自己、壮大自己 ,把为教学、科研服务的职能作用落到实处。1　正确分析把握中专图书馆存在的问题 ,找准主要制约因素1 1　图书馆建设的误区　目前大多数中专学校仍沿袭普高的教育手段和管…     

抗CD_3鼠/人嵌合抗体基因的构建及表达 I.CD_3单抗重链可变区基因的克隆及序列测定

以人工合成的小鼠免疫球蛋白重链可变区(V_H)基因特异的寡核苷酸片段为引物,用PCR法成功地进行了HIT_3a(抗CD_3单克隆抗体)V_H基因的扩增,并将扩增片段克隆进了pGEM-7Zf(+)质粒DNA中,重组质粒序列测定的结果表明,片段大小为353 bp,基因重排方式为VDJ_4。     

STUDY OF GIANT GROUP A MARKER CHROMOSOME IN SEVERAL BURKITT'S LYMPHOMA AND LYMPHOBLASTOID CELL LINES WITH EPSTEIN-BARR VIRUS FROM DIFFERENT ORIGINS

Several Burkitt's lymphoma and lymphobla- stoid cell lines with Epstein-Barr virus derived from different origins have been investigated cytogenetically. Giant group A marker chromosome was detected only in three lymphoblastoid cell lines from nasopharyngeal carcinoma (NPC'). With the exception of the HS2-1B lymphoblastoid cell line derived from a normal donor, the giant group A marker chromosome could not be found in the cell lines from the other sources, including P3HR-l, B95-8, Raji and lymphoblastoid cell lines from tonsil and so on. The results suggest that the giant group A marker chromosome might be associated with NPC. It has been proved by G-banding technic that this giant submetacentric group A chromo- some was formed by the translocation of the short arm of chromosome 3, breaking at the point near to or even involving its centromere, to the distal light band region of the long arm of chromosome l, namely t (1;3) (lp ter ->lq 44:: 3p11+3p ter) and t (1;3) Qp ter+lq 44::3q2b 3p ter). The occurrence rate of the marker chromo- some was only 6.670 half a year after CNL8 cell line was established; 82.0'70 after two years; and 100'/o after five years. The occurrence rate of the marker chromosome was 32To half a year after the NPC80 cell line had been established, and 72a/o after three years. Increase in the oc- currence rate of the marker chromosome in these cell lines was clearly paralleled to the time of the cell lines culture in vitro. In addition, the occurrence rate of the marker chromosome was not the same in differ- ent cell lines. It was only 6.670 half a year after CNL8 cell line was established, while it was 32% for NPC 80 and 63.3'70 for CNL5.     

老年呼吸内科感染的因素及预防

目的：探讨老年呼吸内科感染的因素并且提出相应的预防方案,从而减少患者感染率。方法：回顾性分析2012年8月－2015年8月在我院治疗的145例老年呼吸内科感染资料,观察感染类型比例及原因。结果：145例老年呼吸内科感染患者中主要表现为呼吸系统感染,占70％;其次包括泌尿系统感染、消化系统感染、其他等。结论：导致老年呼吸内科感染的主要因素有心理因素、生理因素以及环境因素等,使用有效干预方式进行护理对减少感染率非常重要。     

肥胖症外科治疗的研究进展

1概念 肥胖病（obesity）系指单纯性肥胖,要除外各种病理性原因引起的肥胖。当前肥胖已经成为了全世界的公共卫生问题,国际肥胖特别工作组指出,肥胖将成为新世纪威胁人类健康和生活满意度的最大杀手。肥胖症是一种社会性慢性疾病,     

CT瘘管造影在复杂性多分支瘘中的临床应用

目的:探讨CT瘘管造影在复杂性多分支窦瘘中的临床应用价值.方法:对7例复杂性多分支瘘管患者进行CT瘘管造影检查,对图像进行最大密度投影(MIP)、多平面重建和曲面重建(MPR/CPR)及三维表面重建(3D-SSD)处理.结果:CT瘘管造影及其后处理影像清晰显示了复杂多分支瘘管系统.2例复杂性多分支瘘管患者经CT瘘管造影分别发现为邻近骶髂关节的病变和盆腔内畸胎瘤所致,另有1例显示了复杂性多分支瘘管病变累及骶尾椎,对比剂进入骶管.CT瘘管造影所见与手术一致.结论:CT瘘管造影有利于复杂性多分支瘘管系统的显示及术前准备.     

前外侧微创入路和传统后侧入路行全髋关节置换术的疗效比较

全髋关节置换术(THA)治疗髋关节疾病已成为一项成熟的技术,能极大改善了患者症状,恢复关节功能。随着微创手术的发展和患者要求生活质量的提高,越来越多的骨科医师关注THA微创切口的选择。但在相关文献中对此仍存在争议,且关于微创和传统术式THA的疗效比较报道还很少。选取本院2009年1月-2010年1月行THA的80例单侧(THA)患者,根据患者手术入路情况,分为微创组(minimally invasive surgery,MIS组)和传统