阑尾原位造口可控性顺行灌肠的临床评价

Objective To evaluate the clinical results of antegrade continence enema via appendi-costomy in situ to treat neurogenic faecal incontinence. Methods 13 patients with tethered cord syn-drome complaeated neurogenic faecal incontinence were performed appendicostomy in situ with intus-susception valve between June 1998 and December 1999 (male 9, female 4, age 6～13 years). After operation,enema were performed via stoma. Results All patients were followed up 2 to 6 years later. All stomas are continent of faeces and flatus. Stoma stricture developed in 2 patients, and atresia in an-other 2 patients. Anus function were increased in 11 patients. Conclusions Antegrade continence ene-ma via appendicostomy in situ is a effective method to treat neurogenic faecal incontinence. It can devel-oped life quality of patients.     

吲哚菁绿荧光血管显像技术在单孔腹腔镜巨结肠根治术中的应用

目的 探讨吲哚菁绿(indocyanine green,ICG)荧光血管显像技术在小儿单孔腹腔镜巨结肠根治术中的应用价值. 方法 2019年11 ～12月我科以ICG荧光血管显像技术引导完成12例单孔腹腔镜巨结肠根治术,长段型2例采用Swenson+ Deloyers法倒转. 结果 12例腹腔镜下确定拟切除病变肠管范围...     

阑尾原位造口可控性顺行灌肠的临床评价

Objective To evaluate the clinical results of antegrade continence enema via appendi-costomy in situ to treat neurogenic faecal incontinence. Methods 13 patients with tethered cord syn-drome complaeated neurogenic faecal incontinence were performed appendicostomy in situ with intus-susception valve between June 1998 and December 1999 (male 9, female 4, age 6～13 years). After operation,enema were performed via stoma. Results All patients were followed up 2 to 6 years later. All stomas are continent of faeces and flatus. Stoma stricture developed in 2 patients, and atresia in an-other 2 patients. Anus function were increased in 11 patients. Conclusions Antegrade continence ene-ma via appendicostomy in situ is a effective method to treat neurogenic faecal incontinence. It can devel-oped life quality of patients.     

纤维结肠镜诊治小儿大肠息肉350例报告

大肠息肉是小儿的一种常见疾病,可引起慢性失血而导致贫血。纤维结肠镜的出现,使小儿大肠息肉的诊断、治疗取得了新进展。我院自1985年1月至1996年5月应用小儿纤维结肠镜诊治小儿大肠息肉共350例,均在住院麻醉下进行,电凝切除息肉402颗,获得满意的治疗效果。     

直肠及结肠息肉的诊断和治疗

息肉是小儿的常见病 ,可以发生在消化道的任何部位 ,约 90 %发生在直肠和乙状结肠 ,为小儿慢性少量便血的主要原因 ,男多于女 ,以 3～ 6岁小儿多见。小儿息肉形成的原因尚未明确 ,一般认为多由肠粘膜炎性病变和慢性刺激形成 ,长期的局限性炎症加上含粗糙物质的粪便经常摩擦 ,可     

26例儿童术后肠套叠的临床研究

目的探讨儿童术后肠套叠的特点诊断、治疗。方法回顾性分析我科在1999年1月-2009年12月期26例术后肠套叠和1416例原发性肠套叠的临床资料。结果本组病人住院术后肠套叠好发于6个月～3岁患儿;88％发生于术后14d内,其中92％为小肠套叠：其手术前诊断率为61％,误诊率为38％。术后肠套叠的临床表现以腹痛、呕吐、腹胀、肛门停止排气和排便为主,血便和腹部包块发生率较原发性肠套叠低（P〈O．01）。26例均接受手术治疗,22例行肠套叠徒手整复术,4例行肠切除吻合术,患儿全部痊愈出院,无1例复发。结论儿童术后肠套叠常发生于腹膜后手术及肠管暴露时间长的手术后,临床症状不典型,其术前误诊率高,确诊后需手术治疗,早期诊断和手术可以减少肠坏死切除的机会。     

小儿胰腺假性囊肿36例诊疗体会

目的探讨小儿胰腺假性囊肿的临床特点及诊疗方法。方法回顾性分析本院近5年来收治的36例胰腺假性囊肿患儿的临床资料,包括年龄、性别、临床症状、治疗方式、治疗效果及有无并发症及复发等。结果男24例,女12例,年龄2岁5个月至12岁9个月,平均8岁2个月。保守治疗15例,其中1例术中发现为胆总管囊肿合并胰腺假性囊肿,行胆总管囊肿切除+空肠肝总管Roux-en-Y吻合术,胰腺假性囊肿保守治疗治愈,6例保守治疗效果不明显择期行囊肿空肠Roux-en-Y吻合术;直接行囊肿空肠Roux-en-Y吻合术14例;囊肿外引流术6例;多发性囊肿1例行部分囊肿摘除+囊肿外引流术1例,所有病例均治愈,术后随访半年至两年未见复发。结论该病的治疗方法较多,应根据病程长短、囊肿大小、部位、与临近器官的关系及有无并发症采取个体化治疗。     

甲基强的松龙对体外肝癌HepG2细胞生长的影响

目的 探讨甲基强的松龙（MP）对肝癌HepG2细胞生长的影响及相关机制。方法 MTT法测定不同浓度MP对HepG2细胞增殖的影响;细胞分为6个处理组：对照组、MPⅠ组（10 ug/l）、MPⅡ组（20 ug/l）、MPIII组（50 ug/l）、MPIV组（500 ug/l）、MPV组（5000 ug/l）;流式细胞仪测定MP对HepG2细胞周期和凋亡情况的作用;荧光定量PCR法测定MP对HepG2细胞VEGF mRNA表达的影响;ELISA法测定细胞培养上清液VEGF浓度。结果 50-5000ug/l的MP作用72h,能促进HepG2细胞的增殖;MP对HepG2细胞周期和凋亡无影响;不同浓度的MP作用72h后,HepG2细胞VEGF mRNA的转录和蛋白表达有显著性差异（P＜0.01）,MP在500ug/l和5000ug/l浓度时, VEGF mRNA表达量分别为（7.293±0.409）拷贝数/ul对数值和（8.231±0.216）拷贝数/ul对数值,高于对照组（4.761±0.624）拷贝数/ul对数值,结果有显著性差异（P＜0.01）,VEGF浓度分别为（11.153±1.552）ug/l和（11.456±1.517）ug/l,高于对照组（7.362±0.510）ug/l,结果有显著性差异（P＜0.01）;。结论 高浓度的MP在体外能促进肝癌HepG2细胞增殖,上调其VEGF mRNA的转录和翻译。     

阑尾原位造口可控性顺行灌肠的临床评价

Objective To evaluate the clinical results of antegrade continence enema via appendi-costomy in situ to treat neurogenic faecal incontinence. Methods 13 patients with tethered cord syn-drome complaeated neurogenic faecal incontinence were performed appendicostomy in situ with intus-susception valve between June 1998 and December 1999 (male 9, female 4, age 6～13 years). After operation,enema were performed via stoma. Results All patients were followed up 2 to 6 years later. All stomas are continent of faeces and flatus. Stoma stricture developed in 2 patients, and atresia in an-other 2 patients. Anus function were increased in 11 patients. Conclusions Antegrade continence ene-ma via appendicostomy in situ is a effective method to treat neurogenic faecal incontinence. It can devel-oped life quality of patients.     

小儿复发性肠套叠诊治体会

目的总结小儿复发性肠套叠的发病特点。方法同顾性分析近5年来收治的47例复发性肠套叠患儿的复发年龄、次数、间隔时间、复发症状以及治疗情况并进行总结。结果47例患儿共复发82次,复发年龄大多数在2岁以内(84％),复发间隔时间大多在1年以内(44例),临床表现多见腹痛、呕吐及腹部包块,血便少见,治疗经空气灌肠复位治愈者40例(85％),手术复位治愈7例(15％)。结论小儿复发性肠套叠与年龄有密切关系,2岁以上患儿复发率明显下降;治疗上应以保守治疗即空气灌肠复位为首选,对于多次复发、灌肠失败及疑有器质性病变者,宜手术探查。