心理干预辅助牙周基础治疗对伴有焦虑症状的中重度牙周炎治疗效果及负性情绪的影响

目的探讨心理干预辅助牙周基础治疗对伴有焦虑症状的中重度牙周炎治疗效果及负性情绪的影响。方法回顾性分析2015年3月—2016年3月兰州大学第二医院健康管理中心收治的92例伴有焦虑症状的中重度牙周炎患者的临床资料,根据资料结果中不同护理方法将其分为对照组和研究组,每组46例,两组患者均予以牙周基础治疗,对照组予以常规护理干预,研究组在对照组基础上予以心理干预,两组均护理干预4周,护理干预结束后比较两组患者的牙周指数与负性情绪,同时记录两组患者对护理的满意度情况。结果两组护理干预后牙周指数各项指标均较护理干预前明显降低,且研究组护理干预后牙周指数各项指标均明显低于对照组;两组护理干预后焦虑自评量表、抑郁自评量表评分均较护理干预前降低,且研究组降低幅度明显大于对照组。结论心理干预辅助牙周基础治疗可有效改善伴有焦虑症状的中重度牙周炎患者的牙周指数,减轻患者的焦虑抑郁程度,更易被患者所接受。     

《太平圣惠方》舌象特点探讨

《太平圣惠方》（简称《圣惠方》）的舌诊在中医舌诊学说的历史发展中具有一定的地位。本文探讨了《圣惠方》舌象的特点,并与其它舌诊源流研究进行了比较。方法特点,一是只研究舌象本身,而不涉及其诊断意义;二是采用频数统计方法。研究发现：（1）《圣惠方》各类舌象、各种舌象与现代舌象比较,现代舌象较为重视的舌色、苔质、苔色在《圣惠方》中出现频数较小,反之,现代舌象较不重视的舌面津液（舌干）、舌态（舌强）、舌体病变（舌生疮）、舌形（舌肿）在《圣惠方》中出现频数较大。（2）《圣惠方》中出现频数较大的上述各类舌象和各种舌象均属可直接影响舌的功能,因而是能“强制性”引起注意的舌象。《圣惠方》中出现频数较小的舌色、苔质、苔色类舌象均属需要有意识观察才能获得的舌象。（3）《圣惠方》舌象的上述特点是因其舌诊发展仍较初步,这从其舌象总的出现频数较小也可反映。     

Regulatory effects of herbal cake-partitioned moxibustion on the expressions of IL-17, IL-23 and their mRNAs in the colon of rats with Crohn’s disease

Objective

To observe the regulatory effects of herbal cake-partitioned moxibustion on Crohn's disease (CD) rat’s colon inflammatory cytokine interleukin-17 (IL-17), IL-23 and their mRNAs, and to investigate the action mechanism of moxibustion in treating CD.

Methods

Forty SPF grade Sprague-Dauley (SD) male rats were randomly divided into a normal group, a model group, an herbal cake-partitioned moxibustion group and a Western medicine group, with 10 rats in each group. Except the normal group, rats in the other three groups were used to make CD model by giving an enema in colon with Trinitro-benzene-sulfonic acid (TNBS). When the models were successful made, rats in the model group had no therapeutic intervention; rats in the herbal cake-partitioned moxibustion group were subjected to herbal cake-partitioned moxibustion treatment at bilateral Tianshu (ST 25) plus Qihai (CV 6); and rats in the Western medicine group were given oral Mesalazine. After treatment, the histopathological changes and inflammatory cytokines IL-17, IL-23 and their mRNAs expressions were observed in descending colon by hematoxylin-eosin (HE) staining, immunohistochemistry (IHC) and real-time polymerase chain reaction (RT-PCR) methods.

Results

Colon tissues of TNBS enema rat models showed cracks-like ulcers accompanied by mucous layer inflammation, granulomas, and inflammatory cytokines IL-17, IL-23 and their mRNAs expressions were all higher than those in the normal group (P<0.01); after intervention, colon tissue cracks-like ulcers and inflammation degree reduced, inflammatory cytokines IL-17, IL-23 and their mRNAs expressions were all significantly decreased (P<0.01) in the herbal cake-partitioned moxibustion group and the Western medicine group.

Conclusion

Herbal cake-partitioned moxibustion may improve colon tissue ulcers and relieve intestinal inflammation by down-regulation of IL-17, IL-23 and their mRNAs expressions in CD model rats’ colonic mucosa.

     

Comparative study of electroacupuncture and moxibustion in influencing Tianshu (ST 25) regions mast cells in visceral hyperalgesia rats

Objective

To evaluate and compare electroacupunctures (EA) with different parameters and moxibustion at different temperatures influencing the activation of mast cells (MC) in Tianshu (ST 25) regions of visceral hyperalgesia model rats.

Methods

Rats (except for model group) respectively accepted 1 mA or 3 mA EA or moxibustion at 43 °C or 4 °C to stimulate Tianshu (ST 25) points after randomization of the fifty visceral hyperalgesia model rats, and then were compared with that in model and normal groups. Number, degranulation numbers, degranulation rates in Tianshu (ST 25) regions MC of rats in each group were observed using toluidine blue staining. Abdominal withdrawl reflex (AWR) score was used to evaluate the rat visceral hyperalgesia reactions.

Results

Compared with the normal group and the model group, MC numbers (P<0.05, P<0.01, P<0.01, P<0.01), degranulation numbers and degranulation rates (P<0.01, P<0.01, P<0.05, P<0.01) of Tianshu (ST 25) MC in regions tissues in 43 °C and 4 °C moxibustion groups, and 1 mA and 3 mA EA groups all increased significantly. Compared with the model group, AWR scores were significantly lower in 43 °C and 4 °C moxibustion groups, and 1 mA and 3 mA EA groups under the stimulation of 20 mmHg, 40 mmHg, 0 mmHg or 80 mmHg colorectal distension (CRD) (P<0.05 in 1 mA and 3 mA EA groups under the stimulation of 20 mmHg, P<0.01 in the other groups). AWR scores in 43 °C and 4 °C oxibustion groups under the stimulation of 20 mmHg, 40 mmHg, 0 mmHg or 80 mmHg CRD were not significantly different from those in the normal group (all P>0.05); AWR scores in 1 mA EA group under the stimulation of 0 mmHg or 80 mmHg were significantly higher than that in the normal group (P<0.01); AWR score in 3 mA EA group under the stimulation of 0 mmHg was significantly higher than that in the normal group (P<0.01), and AWR scores in 3 mA EA group under the stimulation of 20 mmHg or 80 mmHg were also higher than that in the normal group (P<0.05). AWR scores were higher in 1 mA EA group under the stimulation of 40 mmHg or 80 mmHg than that in 4 °C moxibustion group (P<0.05); AWR score was higher in 3 mA EA group under the stimulation of 40 mmHg than that in 4 °C moxibustion group (P<0.05).

Conclusion

There are differences among EA of different parameters and moxibustion of different temperatures in activating on Tianshu (ST 25) regions MC of visceral hyperalgesia model rats, as well as in improving the visceral hyperalgesia reaction. The effect of 4 °C moxibustion is the most significant.

     

浅析张景岳的阴阳思想

张景岳作为我国明代的医学大家,对阴阳的理解和认识有其独特之处,在继承了前人的阴阳观的基础上,对于阴阳一体,一分为二论述更加详细,阴阳变化,从一而生,互根互用,并提出了阳非有余,阴常不足的学术理论。张景岳将阴阳理论运用于临床,为临床上重视真阴为本,补肾中运用育阴以涵阳及扶阳以配阴等治疗大法提供了重要的理论依据,并创左归丸、左归饮、右归丸、右归饮等补肾良方,对中医理论及临床的发展都有极大的贡献。     

容易被癌症瞄上的四种性格

癌症的成因很多，然而不少肿瘤学方面的专家都不约而同地强调心态对癌症的影响是很大的。研究表明，大多数癌症患者都有以下“癌症性格”。     

药用植物学野外实习教学方法和综合测评方式的改革与创新

结合科学研究的方法，立足山东药用植物资源，强化药用植物学野外实践环节，改革传统的教学方法和考核手段，采取分组带着专题实习、普遍认药与专题调查相结合、标本采制与药材鉴定相结合、专业实践与社会调研相结合等的教学方法。初步建立了综合学生论文成绩考查、药用植物认知考核、标本制作规范考评、社会调研情况和实习纪律等综合测评的考核方法体系。     

不同产地百合药材中无机元素的分析与评价

目的:对不同产地百合药材中无机元素进行分析评价。方法:采用微波消解样品,电感耦合等离子体-原子发射光谱法ICP-AES(inductively coupled plasma-atomic emission spectrometer)测定两个主产地35批百合药材中20种无机元素的含量,并用EZ info、SPSS软件对数据进行分析。结果:百合中K、P、Mg、Ca、Na、Si、Fe、Al元素含量较高,含量范围分别为7.200×10~3~1.955×10~4μg·g~(-1),1.114×10~3~2.982×10~3μg·g~(-1),450.525~772.953μg·g~(-1),276.633~827.536μg·g~(-1),51.884~871.821μg·g~(-1),47.523~540.714μg·g~(-1),46.847~595.202μg·g~(-1),20.592~264.639μg·g~(-1),所有样品中均未检测到Hg。以20种元素含量为变量,进行主成分分析,绘制PCA(principal components analysis)得分图,35批百合药材被分成以产地为区分的两组。再结合直观的变量重要性投影值VIP(variable importance in the projection)处理结果综合给出各变量的权重系数,得出两产地主要的差异性元素为:K、P、Fe、Si、Na。结论:研究结果可为百合药材的种植栽培与质量控制提供依据。     

对农村医学的展望

日本第一次农村医学会是在1952年召开的,迄今已有34个年头,农村的情况已经发生很大变化,当时寄生虫病、传染病,特别是结核病的蔓延甚为猖厥,农村居民几乎都处于营养不良状态,农家贫穷,既无文化,又不卫生。而自60年代始,随着全国经济高速发展,农家的收入也迅速增长,几乎与城市劳动者相等或更高些,农村生活也呈现“城市化”。于是,农村医学是否还有存在的必要,不免