肝病患者血清T_3、T_4的变化及临床意义

一些作者认为T_3及T_4与肝脏病变程度有关,在严重肝脏疾病中,血中甲状腺激素降低,出现低T_3综合征,但临床报道并不多见。为探讨各型肝病的T_3、T_4水平及其与肝病预后的关系,我们对各型肝病103例患者血清T_3、T_4进行了检测,现报告如下。     

氨茶碱治疗新生儿呼吸暂停41例护理体会

氨茶碱治疗新生儿呼吸暂停４１例护理体会漳州市医院儿科连莲淑林彩凤新生儿尤其是早产儿，呼吸中枢和呼吸系统发育不够成熟，呼吸调节能力差，在呼吸系统疾病或全身性疾病时易出现呼吸暂停。呼吸暂停、缺氧首先引起脑细胞损害，甚至缺氧性脑病。我院近两年来，采用氨茶碱...     

解剖学教学的艺术感染力

人体解剖学是一门形态科学,是医学生接触最早而又是重要的医学启蒙学科之一.它提供了大量的基础知识和医学名词,记忆性的东西特别多,学起来比较枯燥.提高解剖学教学的艺术感染力可提高学生的学习兴趣,增加对解剖学的求知欲,从而学好解剖学为后续课程打好基础.1 形成引人入胜的良好开端 心理学家认为,当人们接触任何事物时,最初给他留下的印象是至关重要的,所以讲好第一次课是很重要的.如果教师能以整洁的仪表、安祥和蔼的态度、清晰悦耳幽默动听简洁准确的语言将学生带入一个崭新的天地,便会产生一种魅力,     

人工合成人黄体化激素获得成功

合众国际社6月10日芝加哥消息:东弗吉尼亚医学院的研究人员报告,他们成功地合成了人生殖系统的一种主要激素. 基因工程方法制成的人黄体化激素与具有诱导妇女排卵和诱导男子精子产生作用的天然激素在生物学特性上是一致的.合成激素名为重组DNA人黄体化     

全国卫生工作会议综述

在举国上下认真贯彻党的十四大精神,加快改革,扩大开放的大好形势下,1993年全国卫生工作会议于元月中旬在北京举行。会议的主要议题是学习贯彻党的十四大精神,总结交流卫生改革与发展的经验,进一步解放思想,统一认识,研究部署1993年的卫生工作任务。会议在听取卫生部的工作报告和15个省、市的经验交流之后,主要围绕着解放思想,更新观念,卫生事业发展如何同市场经济相适应,如何用好关于第三产业的有关政策,深化卫生改革如何与落实农村卫生、预防保健结合起来,如何坚持两     

颅内恶性脑膜瘤13例报告及文献复习

目的 :探讨颅内恶性脑膜瘤的临床表现、影像、病理特点和治疗。方法 :复习 1980 2 0 0 0年经治疗的 13例恶性脑膜瘤 ,结合近期文献进行分析。结果 :仅以临床表现和影像学检查尚无法在术前完全与良性脑膜瘤区分开来。全组病例均行手术治疗 ,术后均复发。结论 :恶性脑膜瘤的治疗以手术治疗为主 ,复发率高 ,生存期与手术切除程度及术后是否放疗有关。     

抑郁发作自杀未遂患者脑源性神经营养因子水平及其相关因素研究

Objective To investigate the possible role of brain-derived neurotrophic factor(BDNF)in the pathophysiology of attempted suicide in depressive episode patients.Methods The subjects were 23 depressive episode patients who had recently attempted suicide.24 depressive episode patients without suicide attempt.and 30 sex-age-and education matched healthy controls.The Hamihon Depression Rating Scale-24 items(HAMD24),Beck Helpless Rating Scale(BHS)and Self-rating Idea of Suicide Scale (SIOSS)was used to evaluate the severitv of symptoms.The seruln level of BDNF was detected with sandwich ELISA.Pearson correlation coefficients wag used to measure the correlations between serum BDNF and the related illness variables.Results There were significant difierences in the serum level of BDNF between patients with attempted suicide,pailents without suicide attempt and normal controls(F=21.927,P＜0.05).Post hoc analysis showed the serum BDNF levels in patients with attempted suicide [(57 ±16)ng/L]were lower than that in patients without[(75±28)ns/L;P＜0.05],and were lower in patients without suicide attempt[(75 ±28)ng/L]than that in normal controls[(111 ±39)ng/L;P＜0.01].In patients with attempted suicide,the serum BDNF was negatively correlated to the duration of depressive episode(r=-0.541,P=0.008),the mean BHS score(r=-0.494,P=0.017)and the mean SIOSSscore(r=-0.754.P=0.000).Conclusion The results suggest that the decreased serum brain-derived neurotrophic factor is related to the pathophysiology of attempted suicide in depressive episode patients.     

EVALUATION OF IMMUNOHISTOCHEMICAL DIAGNOSIS OF RHABDOMYOSARCOMA

Objective To evaluate the sensitivity and specificity of regularly used immunohistochemical markers, including Vimentin (Vim), Desmin (Des), Myoglobin (MG), Myosin (MS), Smooth-muscle actin (SMA) and Sarcomeric actin ( Sr-A ) , in the diagnosis of rhabdomyosarcoma (RMS). Methods After resection, 24 RMSs and other childhood tumor specimens were fixed in 10% neutral-buffered formalin and embeded in paraffin. The immunohistochemical staining was performed by LSAB procedure. Heat-induced epitope retrieval of Des, MS, Sr-A was processed in order to enhence positive rate and positive strength. Results Vim, MG, MS, Des, Sr-A, SMA were arranged in the order of sensitivity from higher to lower. About specificity, Sr-A, Des, SMA, MG, Vim standed in a sequence from higher to lower ( the data of MS is insufficient) ; Des, MG, Sr-A possessedhigher experimental efficiency, followed by SMA, Vim in a succession. Conclusion Vim and MG are of the higher sensitivity but lower specificity. On the reverse, Sr-A and Des hoM the better specificity but lower sensitivity. So the combination of multiple antibody reactions shouM be considered to improve the diagnostic ability in poorly differentiated RMS. According to the result of experimental efficiency, we suggest that the combination of Des, MG and Sr-A can make it possible to diagnose the majority of RMS clearly.     

JH-2000血液透析机研制

详细阐述国产JH-2000血液透析机的基本原理、组成和性能.     

误诊的十二指肠腺癌1例

男性,48岁,大学教师.因间断右上腹痛,恶心、呕吐半年,加重3d,伴排尿后下腹不适,于2001年10月18日入院.既往健康,体质量无明显减轻.患者2001年4月开始,进油腻食物时,右上腹痛,恶心、呕吐(胃内容物),呕吐后缓解.此后间断发作,就近治疗,诊断为“胆囊炎”,抗感染输液、禁食、治疗后好转.近3个月来,发作频率逐渐增加,进食稍多或稍快则发生腹痛和呕吐,呕吐胃内容物后禁食则自行缓解.发作时均诊断为“胆囊炎”.3d前,再次发生上述症状,呕吐胃内容物和胆汁,吐后腹痛不缓解,同时伴排尿和下腹不适.