弥散张量成像对颅脑肿瘤与相邻脑白质纤维束解剖关系的评价

目的:评价弥散张量成像技术显示颅脑肿瘤与相邻脑白质纤维束解剖关系的价值。材料和方法:对5例正常志愿者及29例幕上星形细胞瘤及脑膜瘤进行弥散张量成像,在弥散各向异性图、彩色张量图及脑白质纤维束图上分析肿瘤与相邻脑白质纤维束的解剖关系,并对患者术前、术后的临床症状进行评价。结果:(1)9例脑膜瘤及11例Ⅰ-Ⅱ级星形细胞瘤推移相邻脑白质纤维束,患者术后临床症状明显改善。(2)6例Ⅲ-Ⅳ级星形细胞瘤及3例Ⅰ-Ⅱ级星形细胞瘤浸润、破坏相邻脑白质纤维束,患者术后的临床症状未明显改善。结论:弥散张量成像技术在显示颅脑肿瘤与相邻脑内主要白质纤维束的解剖关系方面具有重要价值,对神经外科术前治疗方案的确定具有重要指导作用。     

Goldenhar’s Syndrome associated with congenital cyanotic heart disease

A case of Goldenhar’s Syndrome in a 10 year old girl is reported. The unusual features are the absence of epibulbar dermoid which is one of the major hallmarks of the Syndrome and the presence of an associated Cyanotic Heart disease.     

老年人隐裂牙综合治疗的临床分析

目的：评价老年人隐裂牙综合治疗的临床效果。方法：对114例隐裂牙进行综合治疗，1年后随访观察。结果：114颗隐裂牙中，根管治疗全冠修复的有效率为92．86％，充填治疗组有效率为87．5％。结论：综合治疗可以保留牙体组织并恢复咬合力，是老年人隐裂牙治疗较理想的方法。     

Role of pylorus in mediating cholecystokinin-stimulated satiety in the Zucker rat

Obese Zucker rats are less responsive than their lean littermates to the effects of cholecystokinin-octapeptide on satiety and pancreatic growth and exocrine function. We hypothesized that the hyperphagia observed in obese Zucker rats may be caused by a decreased pyloric contractile response to cholecystokinin, resulting in an increased rate of gastric emptying, decreased postprandial gastric distention, and thus decreased satiety. Pyloric muscle strips from six obese Zucker rats and six lean littermates were mounted in separate tissue baths and isometric contraction was measured in response to acetylcholine and cholecystokinin-octapeptide. The dose-response curves for acetylcholine-and cholecystokinin-octapeptide-stimulated pyloric muscle contraction were similar for both the obese and the lean rats. (For cholecystokinin, D₅₀ obese=4.0±0.6 nM, D₅₀ lean=3.4±0.2 nM;P=0.16). We conclude that the decreased satiety response to cholecystokinin-octapeptide observed in obese Zucker rats is not secondary to a decreased pyloric responsiveness to cholecystokinin.This work was supported by NIH grant AM28303-03.     

中医理论的诠释与"过度诠释"

针对中医理论研究存在着触目惊心的“过度诠释”现象，对其产生的弊端、原因进行了探讨，最后提出克服过度诠释的对策。