依那普利致急性心肌梗死后心绞痛发作二例

依那普利致急性心肌梗死后心绞痛发作二例贾勤惠翟秀军邸亚新陈瑞英例１男性，６８岁，维族。因间断心前区疼痛１０小时于１９９６年１月３０日入院。１９８２年患急性下壁心肌梗死，无高血压及糖尿病史。入院后第６天凌晨３时，突然心前区剧烈疼痛，大汗。心电图示Ｖ１～...     

产超广谱β-内酰胺酶细菌感染防治专家共识

超广谱β-内酰胺酶（extended—spectrum β—lactamases，ESBLs）是肠杆菌科细菌对β-内酰胺类抗菌药物产生耐药的主要机制之一，其预防与治疗已成为临床医生需要面对的重要问题，但国内外缺少相关问题处理的指导性意见。《中华实验和临床感染病杂志（电子版）》编辑部和《医学参考报·感染病学频道》编辑部组织国内部分专家制定本《共识》，以对ESBLs相关问题的处理提供指导。     

规范应用阿司匹林治疗缺血性脑血管病的专家共识

急性缺血性卒中 1.证据:在治疗急性缺血性卒中已经评价过阿司匹林的作用,尚未评价过其他抗血小板药物的作用(包括噻氯吡啶、氯吡格雷、阿司匹林和双密哒莫的复合制剂).目前已经完成两个大规模的临床试验,包括国际脑卒中试验(IST)和中国急性卒中试验(CAST)[1,2],均在卒中发病48 h内应用阿司匹林(IST平均用药在卒中发病后19 h,CAST则是25 h).     

退休职工生命质量评价及其影响因素

本研究目的在于揭示退休职工生命质量的现状及分布规律，初步探索生命质量的影响因素。以生理心理健康量表对１１２名来自不同行业退休职工（≥４９岁）的生命质量进行了测量。结果发现女性心理紧张反应、生理紧张反应发生率较男性高，其中睡眠障碍与头晕发生率两者差异有显著性（Ｐ＜００５与Ｐ＜０００５），而男性慢性疾病发生率较女性高。不同年龄组间生命质量存在差异，＞６５岁年龄组慢性疾病发生率较≤６５岁年龄组高。≤６５岁年龄组生命质量较＞６５岁年龄组要好。不同劳动类型中，以体力劳动者生命质量较脑力劳动者与脑力混合型差。研究发现劳动类型是对生命质量影响的主要因素。     

高原与低浓度一氧化碳联合作用对汽车驾驶员神经行为功能的影响

本文采用自身对照方法,对低浓度一氧化碳驾驶环境中汽车驾驶员分别在海拔2800m、3650m、和4600m地区进行了神经行为功能测试,在三个海拔高度,当驾驶室内气温和风速无明显变化,一氧化碳浓度分别为21.8mg/m~3、23.3mg/m~3、24.7mg/m~3时,驾驶员的神经行为功能随海拔增高而明显变化,消极情绪得分不断增加、积极情绪得分逐渐减少;反映驾驶灵敏度、注意力和精确性的指标得分显著下降;反应时间延长、记忆力减退。三个海拔之间相比较,其差异多数有显著性意义。提示高原低氧环境与低浓度一氧化碳联合作用可使汽车驾驶员的驾驶能力下降,影响行车安全。     

Normal weight for length in newborn infants in whom growth hormone deficiency was later diagnosed

A new model for evaluating leanness/fatness (LeanSDS) in the newborn infant has been used to examine body weight for length in a group of Swedish infants in whom idiopathic growth hormone deficiency (GHD n = 220) was later diagnosed. These infants have earlier been reported to be significantly shorter (median =−0.87 SDS; SDS; standard deviation scores) and lighter (median =−0.60 SDS) in relation to gestational age, than the most recent reference. A group of infants who later developed GHD due to organic etiologies ( n = 92) had normal weight and length for gestational age at birth. Using the LeanSDS model (with intercept 0.0 and regression coefficient 0.7) revealed that these idiopathic GHD infants have weight that is normal for their length (mean LeanSDS = 0.11 ±0.08 (SEM); n.s.) why the abnormality is a reduced linear growth. These findings also indicate that birth length (linear growth) should be given increased attention when size at birth is evaluated.     

耐甲氧西林金黄色葡萄球菌感染防治专家共识

耐甲氧西林金黄色葡萄球菌（Methicillin—resistant staphylococcus autreus,MRSA）感染的流行,已经成为严重的临床及公共卫生问题。自1961年首次发现MRSA以来,MRSA的分离率逐年增加,已成为医院感染重要的革兰阳性细菌,并且多重耐药现象日益严重,部分地区已经出现对万古霉素耐药、中介耐药以及异质性耐药MRSA细菌。     

Effect of antioxidants on amelioration of high-risk factors inducing hypertensive disorders in pregnancy

Background This is a prospective clinical study based on a large sample gathered from multiple centers in China, subordinating to 10th Five-Year Plan of National Science ＆ Technology Progression. We analyzed the high-risk factors inducing hypertensive disorders in pregnancy （HDP） and estimated the potential effect of anti-oxidants administration, including vitamin C （VC）, vitamin E （VE） and Salvia Miltiorrhiza L （SML）, a Chinese herb medicine, in amelioration of the high-risk factors in pregnancy. Methods From April 2005 to July 2006, 4814 pregnant women from 24 national wide cooperative hospitals were involved in this prospective research. The participants were randomly divided into two groups： 1607 cases were in anti-oxidants group with administration of vitamins and SML; 3207 cases were in control group without any medicine given. Every participant was under monitoring for the morbidity of HDP and the high-risk factors were investigated in HDP cases in each group. Results （1）The morbidity of HDP was 3.55% in anti-oxidants group vs. 4.18% in control group. No statistical difference existed between the two groups （P〉0.05）. （2） In anti-oxidants group, the HDP morbidities among three subgroups： VC ＋ VE ＋ SML, VC ＋ VE and SML only, were 5.51%, 3.05% and 5% respectively. It showed no statistical difference among three remedies （P 〉0.05）. （3） The related index of factors affecting HDP showed in intensity sequence as follows： family HDP history 〉 profession 〉 education level 〉 age 〉 body weight. The incidence of HDP in normal population was 3.51%, and the incidence of HDP in high-risk pregnant women （family HDP history, heavy physical labor, low education level （middle school and below）, age 〉40, body mass index 〉24） was 5.84%, which was obviously higher than that in normal population （P 〈0.01）. In anti-oxidants group, the probability of HDP in women with high-risk factors was 3.81%, which was obviously lower than that in control group with high-risk factors at 7.14% （P〈0.01）. （4） In control group, the morbidity of HDP in women with family HDP history （especially with sisters＇）, heavy physical labor, middle school and below, age 〉35 was： 50.00%, 15.22%, 6.33%, 26.28% and 5.75%, respectively, and that in anti-oxidants group was 0, 7.69%, 3.74%, 9.27% and 2.67%, respectively, which was obviously lower than that in control group. Conclusions The high-risk factors prone to induce HDP included： family history of HDP, heavy physical labor, low education level, aging and obesity. No impressive effect of anti-oxidants application was found in preventing HDP in general population but the remedy demonstrated positive effect on preventing HDP in pregnant women with high-risk factors.     

音乐治疗对消化性溃疡抑郁焦虑患者疗效的观察

目的：观察音乐治疗对消化性溃疡抑郁焦虑患者的疗效。方法：对消化性溃疡患者,应用zong焦虑量表（SAS）和抑郁自评量表（SDS）进行问卷调查,结果与国内常模进行比较,诊断存在焦虑抑郁后选出120例随机分为观察组和对照组,各60例。对照组进行常规健康教育;观察组在常规健康教育的同时进行音乐治疗。两组患者治疗3周后进行焦虑抑郁的问卷调查。结果：观察组患者的SAS、SDS评分明显优于对照组,差异有显著性（P〈0．01）。结论：音乐治疗能改善消化性溃疡患者的焦虑抑郁症状,可以促进病人的康复。